AR &26 - 77/ ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEsTsuBsTANCE Identity: MriefxetrurreedctoonatasinPiFnOgSp,erFfCl-u9o5r,ooocrtaansesauclfoomnpaotenewnhticohf mFCa-y2a0l3sFoCb.e(1- Octanesulfonic acid) (CAS # 2795-393).

AR 886 -- 077% TOXICITY TO AQUATIC PLANTS IESTsuBSTANCE Identity: MreifxetrurreedctoontaasinPiFnOgSp,erFfCl-u9o5r,ooocrtaansesauclfoomnpaotenewnhticohf mFCa-y2a0l3sFoCb.e (1Octanesulfonic acid) (CAS # 2795-39-3).

: ACUTE TOXICITY TO FISH AR 826 _ 0510 TEST SUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f9l5u,oroorocatsanaescuolmfopnoantee;n,twohfiFcCh-m2a0y6CaEl.so(b1eOctanesulfonic acid) (CAS # 2795-30-3).

AR 226 -- OLR] ACUTE TOXICITY TO FISH (BLUEGILL) IESTSUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a componenotf FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was not noted.

AR 226 - 0828 ACUTE TOXICITY TO AQUATIC INVERTABRATES (DAPHNIA MAGNA) IESTSUBSTANC 0E 0 Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was not noted.

AR 226 _ 0831 ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3,4.4,55,6,6,7,7,8,8.8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was 628.

cL AR 226 - 0928 CAS Number 1763-23-1, 29081-56-9, 70225-14-8, 2795-39-3, 29457-72-5 / 3M Compan/y 1 Revised: 7/2000 Voluntary Use and Exposure Information Profile Perfluorooctane Sulfonic Acid and Various Salt Forms I.

: July 31, 1981 0: FLUOROPOLTMERS PRODUCTION, TECHNICAL AND MECHANICAL SUPERVISION FROM: RB.

C. t . le a pn E. 1.

BACK TO MAIN BIODEGRADATION (Acclimated Activated Sludge and Sediment Cultures) TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The test substance is a white powder.

ACUTE CONTACT TOXICITY TO TERRESTRIAL INVERTEBRATES (HONEY BEE) TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks field: The 3M production lot number was 217.

BACK TO MAIN 3M ENVIRONMENTAL LABORATORY INHIBITORY EFFECT OF L-13492TO MICROBICS' MICROTOX" TOXICITY ANALYZER SYSTEM REPORT COMPLETED: 7/26/95 Prepared by: 1 Susan A.

BACK TO MAIN SUMMARY OF ANALYTICAL RESULTS: MULTI-CITY FOOD STUDY The Multi-City Study was originally designed by Battelle Memorial Institute (Columbus, OH), to obtain preliminary data about the presence of fluorochemicals in foods and in drinking water to understand the potential sources of human exposure.

BACK TO MAIN Centre Analytical Laboratories, Inc. 3048 Research Drive State College, PA 16801 www.centrelab.com (814)231-8032 Fax: (814)231-1253 or (814)231-1 580 Analytical Report Fluorochemical Characterizationof POTW Effluent Columbus, Georgia (W2336) Centre Analytical Laboratory Report No. 023-014M (Revision 1) Revision Date 3/27/01 Testing Laboratory Centre Analytical Laboratory, Inc. 3048 Research Drive State College, PA 16801 3M Environmental Laboratory Contact Kent R.

harlan STUDY NUMBER 1305602 CELL MUTATION ASSAY AT THE THYMIDINE KINASE LOCUS (TK *) IN MOUSE LYMPHOMA L5178Y CELLS WITH <cC604 AMMONIUM SALT REPORT STUDY COMPLETION DATE: JULY 14, 2010 SCt6ud0y4Naummmboenri1u3m0s5a6t02 Rego Page of 44 1 COPYOF GLP CERTIFICATE ] [------ `GLP-Besichemiinogigu1n09 og.f/GSLCtPhaCotemeplbmieaanncte = HESSEN B Seo Ee GL npekiponeue truOeomcoahaEgrenng Assesmem nt of cnofoordshe s y wihGo SLPHsEcsEi = 8 coesnsy] ror ese Tr B [ES ------ [I ---- DtJi ekTwit0o2m0oe2fn0t8ceio feoOE LY Ccbar sshd dP , desorGLtCoemp eps dls RE ------ e ane foRetetrem.hwiC resoaspeno,tidenren30e.e)war 2000(3 AYouN %) 3,X Nw W BeS (amend Arse GLO nesnd ssfGL. orig Aut SCt6ud0y4Naummmbeorni1u3m05s6al0t2 Report 2 CONTENTS 1 COPY OF GLP CERTIFICATE 2 CONTENTS 3 PREFACE 31 General 32 Responsibilties 33 Schedule 34 Project Staff Signatures 35 Good Laboratory Practice 36 Guidelines 37 Awchiving 3:8 Deviations from the Study Plan 4 STATEMENT OF COMPLIANCE 5 QUALITY ASSURANCE UNIT STATEMENT 6 SUMMARY 7 OBJECTIVE 70 Aimsof the Study 72 RelevofathneTceestSystem 8 MATERIALS AND METHODS 81 Testhem 82 Controls 82.1 Solvent Controls 822 Posilive Control Substances 83 TestSystem 83.1 Reasons for the Choice of the Cell Line L5176Y 84 Cel Cultures 85 Mammalian Microsomal Fraction 9 Mix 85.1 9 (Preparation by Harlan CCR) 852 S9Mix 86 Pre-Teston Toxiclty 87 Dose selection 88 Experimental Performance 88.1 Complete Culture Medium 882 Selective Medium 883 Saline G Solution 89 Size Distribution of the Colonies 810 Data Recording 8.11 Calculation and Processing of the Data 8.12 Acosptabilty of the Assay 8.13 Evaluation of Results 8.14 Statistical Analysis 9 RESULTS AND DISCUSSION 9.1 Conclusion 10 REFERENCES 11 DISTRIBUTION OF THE REPORT Page 3of44 2 3 5 5 5 5 6 6 6 7 7 8 9 0 2 12 2 3 1i4 14 14 15 15 15 6 16 16 6 7 18 18 18 18 19 19 20 21 21 2 23 2 2 2 C`S6tu0dy4Naummmboenri1u3m05s6a0t2 Report CONTENTS CONTINUED 12 ANNEX|: TABLES OF RESULTS 12 Pre-Experiment 122 Main Experiment 12.21 Experiment, Culture | 12.22 Experiment, Culture I 12.2.3 Graphical summary of experiment | Culture | 12.2.4 Graphical summary of experiment | Culture I 12.2.5 Experiment I, Culture| 12.26 Experiment I, Culture I 12.2.7 Graphical summary of experiment l, Culture | 12.2.8 Graphical summaroyfexperiment , Culture I 13 ANNEX II: HISTORICAL DATA Pagedofas 2 2 228 31 Ea 3 36 39 a2 a3 a 3 PREFACE THe:31 General Sponsor Stay Monitor Test Fast -- iaHttohesCTeAhyLmLiydAmipnreMoKmiOanaLNseE1L7So8AcYLusTco(lTsK) VS2i0Ol0Le2V1LAoBYmoSbatOrLedEi1XaI)2S0 SpA or aa arianCyttet Cell Research GH (innHsaorenloanRLCooCpmpRe)aerinsissen 19 3.2 Responsibilities Sty Doctor EE Deputy Stuy Director J Management J---- Head of Qualify Assurance Unit JETER-- 3.3 Schedule Experiment Sarg Dae Experimental Completion Dat Janay 05,2010 February 22, 2010 3.4 PrSotaj ffSe ignc atut res Study iector ------ 3.5 Good Laboratory Practice `Chemikaliengesetz* (Chemicals Act) of the Federal Republic of Germany, "Anhan1g 5002, and arena erin ted dy02,2000 (BGI . 1146) OECD Princes of Good Laborstary Pract, a eid n 1997 (COT BB Final] 3.6 Guidelines c`SCt8ud0y4Naummbmeorni1u3m05s6al0t2 Report 3.7 Archiving Harlan CCR will archive the following data for 15 years: Raw data, study plan, report, and a sample of the test item.