Northwest Bioanalytical a Study No.

Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

Hollyhouse Inc.

- ADIETARYLCS0STUDYWIrToHTsHENORTHERN BOBWHITE WILDLIFE INMTELRANABTRIEOQNUAELSLTTDN,o.PRO0J2E7C23T NO 454.103 S5r U0S.

AR226-1880 Overview of APFO/Telomer Active DuPont/DuPont-Sponsored Projects Presented to US EPA Robert W.

: AR226-1919 H18636: Slide Reviewofpancreas lesions fram DuPont APFO Study DateofReview: 28 November 2001-11-29 Reviewing Pathologists: Dr EE McConnell and DrIR Foster Study No: HN-18636 SWyt1u4d,y6T4i3tl.e: Combined Chronic Toxicity/Oneogenicity Study with Linuron, C8 end Conclusionofthe review: th"eThierfoivnerdailnlgsc.onTclhuesiroenvoifewthceonrfeivrimeewod fthtehcetarwcoinsotguedniiecs ewfafesctthoaftAtPheFyOweirnethneotDiunPcoonnstisstteundty in awnads tchoensmiodsetreHdike0lbyeeaxdpelacnraetaisonedforstehensJiactkioffvointthyaencdoegveenleotpimceneftfoefctpofaAnPFcO raacietnhaaere3tfMfeiscttcsu,dy sctoumdbyisnheodwweidtthhaenfuulnldesrp-ercetprourmotnfgoAfPFthOe-iancdinuacrehdypaecripnlaarspiraotlhiafterwaatisonpsrefsrenotm. hyTpheerpDluasPioant tahsroaurgefhlteoctciaonrocfinionmaad.eqIutsahcoyuilndtbheenoorgtiendatlhtinttehrepcroetmamtieonnotfotnuesntuddyeburtrmeerepilsyonroretfiltenctitesnntdheged. . yefaacrtsthsatiknnotwhlcee3deMge,santdwdaiusscrriedmpionratytedi.onAoffhienaslecsuobtlne pfanciroerafttimicsalcesotinocnilsu,sohiaonsnadavwaanictesdaimnotrhee exteasive reviewofthe pancreas slides from the 3M study to be carried out by Dr McComnell.

AR226-2023 INTEROFFICE MEMORANDUM Data: Fronis Dept; T&l NO; 12-Oeo-1S96 02;30pm EPT ANTHONY J.

AR226-2053 !

AR226-2112 Test Results Sample Date Range Concentration Range Action Level - n < - ' g----CT'g In =;-TC d W3-;i u s t r i eJ :;ry;nTip;'-ra-j<j,,-jt ; ';=t.S-CT,-.-'----- -:----- -:-- JHygie ; -,- : - ne - - ----' 1/1/84 12/31/84 100% Sample Dt Sample Duration Type Employee Name BTO: 08 LOG; 701 TEFLON FINE POWDER DRYER--EAST SIDE (K 11QB4 46247 3SO Z 1/13HB4 46248 380 Z 3/11/84 46240 3SO Z 4/10/84 46250 398 Z 5f7/84 48251 390 Z 6084 46252 7/284 46233 380 Z 360 2 7/30/B4 46254 360 2 8C484 4625S 330 Z 9H23(B4 46256 420 Z 10(21/84 46257 3GO Z 12/17/S4 46258 370 Z Pers Chemical C-8/FC-143 C-6/FC-143 Cfl/FC-143 C</FC-143 <>a/FC-143 C-8/PC-143 C-WG-143 C-8ffC-143 08/FC.143 (>8/FC-143 C4/FC-143 08/PC-143 Cone Unit Percent 82 MPB 0.19 MP8 0.31 MPB 0.21 MPB 0.47 MPB 0.29 MPB <0.08 MPB 03B MPB OJ53 MPB 0.02 MPB 036 MPB 039 MPB 146425%* 33.6% 55.4% 375% 83S% 51.8% 5.4% 50j0% 94.6% 110.7%** 43% 69,6% BTO: 06 TEFLON U3C; 702 FINE POWDER DRYER CONTROL ROOM (ALSO SEE TTF031 1/23(84 36566 345 Z C-8/FC-143 1/27/S4 36567 420 Z C.8/FC-143 2/20(84 36568 3/17/84 36668 360 Z 360 Z 0-8^0.143 C-fl/FC-143 6/12<B4 36670 385 Z C-e/PC-143 7/8184 36571 340 Z C-8/PC-143 8/4(84 36572 420 Z Ofi/FC-143 10/2/B4 36573 360 Z C^/PC-143 11/24(84 36574 390 Z C-e/FC-143 1203(84 3S5?

AR226-2304 Based on RAGS (Superfund) guidance, Exhibit 6-11 Intake (mg/kg-day) =CWxlRxEFxEP BWxAT !

SITE SCREENING LEVEL ASSESSMENTS FOR PFOA AND THE RELEVANCE OF SOIL SAMPLING Date: OctobertO, 2003 Project No,; 18983753.00034 ^ CORPORATE REMEDIATION GROUP An Alliance between DuPont and URS Diamond Barley Mill Plaza, Building 27 Wilmington, Delaware 19805 EXP001453 SHe Screera'ng Level Assessments for PFOA and the Relevance of Soa Sampling Table of Contents TABLE OF CONTENTS Executive Summary. 1.0 Introduction ..... 2.0 Data Presentation................................................................................................ 2.1 Development of a Generalized PFOA Screening Level Site Conceptual Model...............,................................................................................................3 2.2 Laboratory Studies of PFOA and Field Sample Verification........................... 4 2.2.1 The Behavior of PFOA in Water......................................................... 5 2.2.2 Adsorption/Desorption of Ammonium Perfluorooctanoate to 2.2.3 2.2.4 Soil.......................................................................................................5 Little Hocking Water Association Investigation Results..................... 7 Washington Works RFI Soil Sampling Results................................... 8 3.0 Summary... .10 4.0 References. .11 Table I Table 2 Table 3 Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 TABLES Washington Works RFI Soil PFOA Results '-- Washington Works RFI Surface Soil PFOA Results Washington Works RFI ADP SWMU Soil PFOA Results FIGURES PFOA Screening Level Assessment Model Comparison of K^s for PFOA and Other Chemicals Little Hocking Water Association Well Field Soil PFOA Results Washington Works RFI Soil PFOA Results Washington Works RFI Surface Soil PFOA Results Washington Works RFI ADP SWMU Soil PFOA Results soil position paper4.doc Oct. 20, 03 Wilmington, DE EXP001454 Site Screening Level Assessments for PTOA and the Relevance of SoB Sampling _____EXCCUtlVe Summary EXECUTIVE SUMMARY DuPont's extensive implementation of both media specific assessment modeling tools and comprehensive on-site and off-site soil, surface-water, and groundwater monitoring for perfluorooctanoate1at the Washington Works site in West Virginia allowed for compilation of a generalized screening level assessment model.

AR226-2567 1 N OF To; From; TE R PICE MEMO Mr.

AR226-2589 BEST COPY AVAILABLE ASH027845 WHOLE DOCUMENT EID781125 EID781125 ASH027a46 EID781126 EID781126 -- v m s .. ...rf.

AR226-2651 41 AR226-2651 Verification Study for Air Dispersion Modeling at Fenceline Draft Plan October 2003 Table of Contents I.

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