5 International Research and Development Corporation SPONSOR: TEST MATERIAL: SUBJECT: 3 Company Fluorad Fluorochemical FC-143 ASctuutdey OirnalRatTso.xicity ng) Whi WiDilrseocnto?

AR 226 0877 ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity: A mixture containing perfiuorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-783. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR226-3374 m HASKELL LABORATORY Common Name: Ammonium Perfluorooctanoate (C-8) Chemical Name: Octanoic acid, pentadecafluoro-, ammonium salt CAS Registry No.: 3825-26-1 Chemical Structure: CFs - CF2 - CF2 - CF2 - CF2 - CF2 - 0 0 CF2 - C - 0-+NH4 Physical Properties: Form: Molecular Weight: Boiling Point: Melting Point: Density: Recommended AEL 0.01 mg/m3 (8-hour TWA), skin General Toxicity White powder 431 Sublimes @ 110C ---- ----- Ammonium perfluorooctanoate (C-8) has moderate acute oral toxicity with an LD50 in rats of 470 mg/kg A----Jlll981b).

Experiment No.: Conducted At: Dates Conducted: Conducted By: Acute Oral Toxicity Screen with T-2574CoC in Albino Rats RECEIVED OCT - @ 1979 31 TOXICOLOGY 0979AR0037 Safety Evaluation Laboratory Riker Laboratoriest Inc-t St. paul, minnesota August 6, 1979 to September 6, 1979 i?

ACUTE TOXICITY TO FISH (RAINBOW TROUT) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, oras a component ofFC-206 or L3243. (1-Octanesulfoniacid)(CAS # 2795-39-3).

BIODEGRADATION (BOD/COD) TEST SUBSTANCE Identity:A mixturecontainingperiulorooctanesulfonatew,hich may alsobe referredtoas PFOS, FC-95, or as a component ofFC-206A. (1Octanesulfoniaccid)(CAS # 2795-39-3).

a ore Contains No Cpy Ivo Viesk Oroerln-R3asn0gaecreicndiinngTTaotxsicity Study g E=R 2 Exportaent to.: Dosing seared: Recovery Intervals Completed: study Direotor: zesting Factitey: vromsoz october 3, 1979 November 15, 1979 6. n. stetfen, 35 S on J] = 43 w>l HsaoteesthyauitEa,veaclWauiuamntmritaoasnso:rLabTooreastory sponsors & EPA-OTS vTf.onric.eecWieaegdcyomSiocrkvices St.

BIOACCUMULATION TEST SUBSTANCE Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N1.-1E,t2,F2O.S3.E3,A4l,c4o,h5o,l5,o6r,6F,M1-.374,82,28.,8-(h1e-pOtcatdaenceafsluulofroon-aNm-i(d2-eh,ydNr-oextyheytlh-yl)-, CAS # 1691-09-2) Remarks: Material is an off-white, waxy solid of uncharacterized purity.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, or as a component ofFC-206 or L3243. (1-Octanesulfoniacid)(CAS # 2795-39-3).

ARNE -Oyoo ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: Perfluorooctanesulfonylamido(ethyljacetate; may also be referred to as PFOSAA, FC-128 or as the major component of FC-127, FC-129, FC-109, or FC-109-X.

: AR R26 -- O776 BIODEGRADATION (BOD/COD) IESTs0u 000B 000 sTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95,or as a component of FC-206 or L3243. (1-Octanesulfonic acid) (CAS # 2795-39-3).

AR226-3330 TRipmP Copy No. \^) _ Distribution - Last Page FC-143 IN THE M.

CC : AR726-0359 SUMMARY OF HISTOPATHOLOGICAL EXAMINATIONS OF FATHEAD MINNOW (Pimephales promelas) EXPOSED TO 78.01 FOR 30 DAYS.

AR226-2089 TA3LE 1 HAXIMIH4 1-ER, S-'dR A-\1) AKKUAL HEAM C-8 COKCENTRA'n :ONS 0V ES TE tIV YEAS (1973-:1977) PERIOD OiF RECORD AT SL2:CTED .

BIOCONCENTRATION TEST SUBSTANCE Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N1:-1E,2{,F2O,3S.E3.A4l,4c,o5h,o5l,6o,r6,F7M.7-,384,2828.