.

BACK TO MAIN ACUTE TOXICITY TO AQUATIC INVERTEBRATES (FRESHWATER MUSSEL) REVISED Tissue analysis is now included.

3M MEDICAL DEPARTMEENT, CORPORATE TOXICOLOGY ProtocolforStudy No.

FlazletonInc. box@7545 dison,Wl -53707-7545 4 so@ aliveries3:301 Kinsman Blvd.

DEPARTMENT OF THE NAVY NAVAL RESEARCH LABORATORY 4555 OVERLOOK AVE SW WASHINGTON DC 20375-5320 3905 Ser 6180/0415 mOCT 0 $ From: Commanding Officer, Naval Research Laboratory To: Commander, Naval Sea Systems Command (Code 05R42 E Minor) Subj: RESULTS OF QUALIFICATION TESTING OF 3% (LI 5603B) AND 6% (L15606B) AQUEOUS FILM FORMING FOAM (AFFF) LIQUID CONCENTRATE FIRE EXTINGUISHING AGENT MANUFACTURED BY THE 3M COMPANY.

Pathology Review of Reported Tumorigenesis in a Two Year Study of FM-3924 in Rats November 25,1998 BY Pathology Associates International 6217 Centre Park Drive West Chester, Ohio 45069 Telephone (513) 779-9600 Fax (513) 779-9603 003099 Pathology Review of Tumors Reported in Rats Given FM-3924 Introduction: This report presents an independent assessment of tumorigenesis data obtained from a study to determine the chronic toxicity and carcinogenic potential of the fluorochemical FM-3924 in rats.

BACK TO MAIN Study Title Growth and Reproduction Toxicity Teat with N2803-2 and the rreshwater Alga, S1tnaetrua caprlcornutua Data Requirement) Guideline Number U.s.

BACK TO MAIN ACUTE TOXICITY TO AQUATIC INVERTEBRATES (FRESHWATER MUSSEL) REVISED Tissue analysis is now included.

AR^-Sg BIODEGRADATION TEST SUBSTANCE Identity: Perfluorooctanesulfonate, Lithium salt; may also be referred to as PFOS Li salt, FC-94, or FC-94-X. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-, lithium salt, CAS # 29457-72-5) Remarks: The test sample is a mixture of the test substance in water (approximately 24.5% test substance and 75.5% water).

ACUTE TOXICITY TO FISH - /t / iw a f i-0111 TEST SUBSTANCE_______________________________________________ Identity: Perfluorooctanesulfonate, Lithium salt; may also be referred to as PFOS Li salt, FC-94, or FC-94-X. (1-Octanesulfonlc acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-, lithium salt, CAS # 29457-72-5) Remarks: Test sample was taken from 3M production lot #1.

AR22-W* 0 STABILITY IN WATER (HYDROLYSIS) TEST SUBSTANCE Identity: N2-(N-methylperfluorooctanesulfonamido)-ethyl acrylate; may also be referred to as N-MeFOSEA, or MeFOSEA. (2-Propenoic acid, 2[[(heptadecafluorooctyl)sulfonyl]methylamino]ethyl ester, CAS # 25268-77-3) Remarks: Material is an amber, waxy solid, coded THAR3F2.

flRr& 'O 5G\ Summary PFOS Rat Two-Generation Reproduction Study Study Numbers: 3M T-6295.9, Argus 418-008 (in-life), FACT-TOX-012 (analytical).

<gHQ - oy-06. 373 {oz>o g/l7g,a z ) _________________ ________________________________________________ &o A R Z O fc -a W Analytical Laboratory Report ON THE Determination of the Presence and Concentration of Perfluorooctanesulfonate (PFOS) (CAS Number: 2759-39-3) in the Serum of Sprague-Dawley Rats Exposed to Potassium Perfluorooctanesulfonate via Gavage Laboratory Report No.

CAS Number 25268-77-3 3M Company A fe - T * Voluntary Use and Exposure Information Profile N-Methyl perfluorooctanesulfonamido ethyl acrylate , I.

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