AR226-3345 Perfluoroalkylated Substances in the Environment: What are they?

TRADE SECRET AR226-3170 DuPont-448 Study Title H-24616: Influence on Growth and Growth Rate of the Green Alga Selenastrum capricornutum Laboratory Project ID: DuPont-4488 AUTHOR: Terry Lee Sloman, B.S.

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JEFFERSON MEDICAL COLLEGE of THONTAS JEFFERSON UNIVERSITY Daniel Baugh Instituteof Anatomy Department of Anatomy Office of the Directorand Chairman Philadelphia, 19107 (215) 928-7820 November 12, 1982 Dr.

DeterminationoftheWater Solubilitoyf PFOS by the Shake FlaskMethod WATER SOLUBILITY TEST SUBSTANCE Identity:Perfluorooctanesulfonatmea;y alsobe referredtoas PFOS or FC-95. (1-Octanesulfonicacid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassium salt,CAS # 2795-39-3) Remarks: The testsubstance isa whitepowder.

28 Day Percutaneous Absorption Study with FC-99 in Albino Rabbits Experiment No.: Conducted At: Dates Conducted: Conducted By: 0979ABO633 Safety Evaluation Laboratory Riker Laboratories, Inc.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES - Daphniamagna TEST SUBSTANCE IdentityN:-Ethylperfluorooctanesulfomnaaymaildseo;be referrteodas U 1464, ETFOSA, ETPOSA, F-6309, or FX-12. (1Octanesulfonamide,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-N-ethylC-A,S # 4151-50-2) Remarks: Materialisa whitesolid.Sample purityand lotnumber were not recorded.

3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY ProtocolforStudy No.

To: Froin: Subject: Date: Study Files of Riker Experiments Nos. 0680TROO08 OGSOTROO10 0680TROO20 0681TROO95 0681TRO110 068ORROO18 L.

WATER SOLUBILITY TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may also be referredto as PFOA ammonium salt,Ammonium perfluorooctanoateF,C116, FC-1 26, FC-1 69, or FC-1 43.

MICROTOX(D TOXICITY TEST TEST SUBSTANCE Identity:Perfluorooctylsulfonadtied,ecyldimethylammonium salt;may also be referredtoas Fluoroalkyalmmonium derivative[.1Decaminium, N-decyl-N,N-dimethyl-s,altwith 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-loctanesulfoniaccid (1:1)C,AS # 251099-16-8] Remarks: The 3M productionlotnumber was Lot 1.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonamtaey; alsobe referredtoas PFOS, FC-95,or as a component ofFC-203C and L-5440. (1-Octanesulfoniaccid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecapfoltuaosrsoi-u,m saltC,AS # 2795-39-3) Remarks: The 3M productionlotnumber was 501.

DEHYDROGENASE ACTIVITY (TTC TEST) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonawthei,ch may alsobe referredto as PFOS, FC-95, or as a component of FC-603EF. (1Octanesulfoniaccid)(CAS # 2795-39-3).

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:A mixturecontainingperfluorooetanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, oras a component ofFC-603F. (1Octanesulfoniaccid)(CAS # 2795-39-3).

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