Document v1z0G2ZgQkdQ5OaO3Lpj24wj9

.9 Material Tested ----^ E. T. du Font de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine Haskell - HASKELL LABORATORY Sample Ready No. for Testing w. REPORT NO. 723-75 QfHHB Other Codes Material Submitted by ------------11----1----or1g"lc chC AR226-2847 ACUTE ORAL TEST Procedure; The test materia 1 as re-eived was administered by intragastric intubation to young adult in single doses, one animal per dose level. Survivors were sacrificed 14 days later. Results: Dose (mg/kg) 25,000* 17,000 11,000 7,500 5,000 Dose in ml+ 5.8 4.1 2.5 1.8 1.2 Mortality** D - Id. D Id, D - 4 d. S " 14 d. S - 14 d. Clinical Signs Lethal Doses; Piloerection. diarrhea, labored breathing, prostration, wet perinea! area, weight loss and lethargy. Nonlethal Doses: Diarrhea 1-3 days after dosing, lethargy on 3rd day after dosing and congestion 6-14 days after dosing at 7500 mg/kg. Piloerection on 6th day after dosin at 7500 and 5000 mg/kg. Weight loss for 1 day after dosin at 5000 mg/kg and sporatically from 1-14 days at 7500 mg/ w toxicity when administered orally to young adult ChR-CD rats in single mate Letha]^ose(ALD) is 11 ,000 mg/kg of body weight. + Specific Gravity as 1.080 * Administered as a divided dose wr D - ( ) d. = Found dead ( ) S - ( ) d. = Sacrificed ( ) days days after after dosing. dosing. > ^a SB (9 a o K 0- cr *<j < .Company Sanitized. Does not contain TSCA CBS