AR226-2765 FOR DU POKT USE ONLY Copies to: E.

AR226-3125 HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE H-24119: STATIC, ACUTE 96-HOUR SCREENING TEST TO FATHEAD MINNOWS, Pirn ephales promelas PURPOSE: This is a rangefmdmg study designed to provide an estimate of aquatic toxicity using fixed test concentrations and data measurements at predetermined intervals.

ARaRE _ 3255 isd `TRADE SECRET ARaR6_ 3258 Duront11269 Study Tide H-25357: Oral Approximate Lethal Dose (ALD) in Rats Laboratory Project ID: DuPont-11269 AUTHOR: Carol Finlay, B.A.

PFOS: A Se Cladoceran(( .

Acute Toxicityt PFOS) ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:PerfluorooctanesulfonatDeE,A salt;may alsobe referredto as PFOS DEA salt,FC-99, or 3M Sample No. 2. (1-Octanesulfonic acid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafcloumoprdo.-, with2,2'-iminobis[ethan(o1l:]1),CAS # 70225-14-8) Remarks: Test sample isa mixtureofthe testsubstanceinwater (approximatel2y5% testsubstance and 75% water).Allvaluesreported relatetothismixture.No calculationwsere made to adjustforthe actual concentrationofthe testsubstance inthe testsample.

COMPOSITE ANALYTICAL LABORATORY REPORT ON THE QuantitativeAnalysisof Fluorochemicalsin Environmental Samples REPORT No.

ti'704 17.(*00 PROJECT N@l, " 3M TIECTINICA@ NOMOOK 1 Subjcct: JOACCLAf"lAlckj@oh OkFM-34-2-L Ckomm-st .. i- ,, A Object: ...

REPORT AMENDMENT NO. 1 TWO YEAR ORAL (DIET) TOXICITYICARCINOGENICITY STUDY OF FLUOROCHEMICAL FM-3924 IN RATS Experiment No.0281CROO12 The attachedpages include revisions in the first paragraph on page 3 of the Summary and in the third paragraph of page 22 of the Discussion.

HAZLR-T-MN 3Wl KINSMAN BLVD. - P.O.BOX 75a o MADISON.

13) OECD 201-OPPTS 850.5400, Algal toxicity- 96-Hour toxicity test with the freshwater alga, 454A-129 PFBS: A 96-HOUR TOXICITY TEST WITH THE FRESHWATER ALGA (Selenastrum capricornutum) SANITIZED L FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

AR226-9 10% TTHEEOP0ES0FU0FR5EECATNTSDo OG1F4RCOC-W7OT8NH.T0IA2NNUDOOUNSSUHRAAVQTIUCVEHAOALUBSIOLFITY .

AR2%6-0161 ors 3M ME- DSTI4C3:ALStaDndEaPrdAPRroTceMdEurNeTfo,r LCivOerRSPubOceRluAlaTrEFraTctOioXnaItCioOn L- OGY Study Objective: 0R-S Perfluorochemical compounds suchas perfluorooctane sulfonate (PFOS) have. been linked with reduction in serum cholesterol levels and liver has been identified as the primary target site.

ARARG - ISIS | - --| || TSh CA NCm IC NOTIFICATI-ON FORM FOR CBI DOCUMENTS || Docker Numeer: OR 336 DOCUMENT CONTROL NUMBER: 630300 codf DOCUMENT DATE: ___F- 4-22 Document Type: Doc TE 4> 3323 soe =E B3355 @ 2 C(TFHCElTD)SOUCCNAUDMREEERNQSUTEIRCRETEFISEOERNEP1NA4CTOEOFDPATRHBOEOTVTEEOCXTIISCFCRSLOUAMIBMSPETUDABNALCSIECCSDOINCFSOICNDLTEONRSTOUILRAELASCBCTUBS(IITNSOECBSATS)A.IINNEFTDOHRAUMTNADSTEEIRCOTNION RTESLCEAA,SAEONDRDITIIMSPOCSELSCOROISMFUISNURACLEHPEINNAFLOTRIMEASTIFOONR.

OCTANOLMWATER PARTITION COEFFICIENT EST SUBSTANCE Identity: NN--eEtthyFlOpSerEfAllucoorhooolctoarneFMs-ul3f4o2n2a.mid(o1e-tOhcatnaonle;sumlafoynaalmsiodeb,e referred N-ethyl- to as 1.1,2,2.3,3.4,4,5,5,6.6.7.7,8.8,8-heptadecafluoro-N-(2-hydroxyethyl)-, CAS # 1691-992) Remarks: Material is an off-white, waxy solid.

BIODEGRADATION TTEESSTTSSUUBBSTAANNCGEE 000000000000 Identity:Perfluorooctanesulfonylamido(ethyljacetate; may also be FreCf-e1r2r7ed, tFoC-a1s2P9,FOFSCA-A10,9,FCo-r1F2C8-1o0r9a.sX.the(Gmlaycjionre,coNm-petohnyeln-tN-of [(heptadecafluorooctyl)sulfonyl]-, potassium salt, CAS #299151-7) .