Document yoJazbrYR5wMxLGmjXN3wr8X

AR226-3145 DuPont-4002 HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE H-24390: STATIC, ACUTE 48-HOUR SCREENING TEST TO Daphnia magna PURPOSE; This is a rangefinding study designed to provide an estimate of aquatic toxicity using fixed test concentrations and data measurements at predetermined intervals. GENERAL INFORMATION WORK REQUEST NUMBER: HASKELL NUMBER: ^43 SERVICE CODE: MATERIAL TESTED: SYNONYMS/CODE SPONSOR:_J2uPont ID:UU NOTEBOOK SUBMITTER'S: N/A NOTEBOOK NUMBER:^ot provided by sponsor COMPOSITION: CONTAMINANTS:. CAS REGISTRY PURITY; MSDS No.: not provided by sponsor Electronic MSDS DU007357, 10097 PP Page 1 of 2 TEST CONDITIONS Nominal concentrations tested: 0,1.0,10,100, and 1000 mg/L. Nominal Concentration (mg/L) 0 1.0 10 100 1000 Test Initiation (0 hours) Dissolved ' Oxygen (mg/L) pH 9.8 7.2 9.9 7.3 9.9 7.3 9.9 7.3 9.9 7.3 DuPont-4002 Test Completion (48 hours) Dissolved Oxygen (mg/L) PH 9.0 6.8 9.1 7.0 9.1 7.1 9.1 7.3 8.9 7.4 H-24390: STATIC, ACUTE 48-HOUR SCREENING TEST TO Daphnia magna, CONTINUED RESULTS Based on visual observations; the water control and 1.0 mg/L test solutions were clear with no color throughout the test. The 10 and 100 mg/L test solutions had suspended material present throughout the test. The 1000 mg/L test solution was slightly cloudy with suspended material present throughout the test. Immobilities at the end of the study were 0, 0, 0, 30, and 30% in the 0,1.0, 10,100, and 1000 mg/L test solutions, respectively. At test end, lethargy was present in 14% (1/7) of the remaining mobile daphnia in the 1000 mg/L test solution. All other surviving daphnids appeared normal at 'the end of the study. The 48-hour ECso, based on nominal concentrations and immobility, was greater than lOOOmg/L. All water quality parameters were within acceptable ranges during the exposure. CONCLUSIONS H-24390 exhibited low toxicity in a 48-hour, unaerated, static acute test using Daphnia magna. WORK BY: WORK / AUTHORED BY: ^aiiM h-QclMsi VLa---u--ri<e- Dk. BTo-n*c-^hle-l-lfeToxicology Associate ^L.Q<T^- RichardF. Rossi Toxicology Associate w- rrkoJi-o^ Date \><-y<yojj^- AXO Date APPROVED BY: ^Sai^ Alan Samel, B.S. Research Ecotoricologlst A^7^J_2^S^ Date Company Sanitized. Does not contain ISCACB8 Page 2 of 2