7 Gchaa7r2sa7hu2n0t00 01:39 PM TT o E geraldmaknednencec/yD@OU/SUASdEuPpAo/nUtSoGmEPA, pateLnei@epa gov Subject Request for change in submission da for PFOR exposure infomation GTTehraarnyk.s for your EMaiyw2i, t20c0o0rtleitteoirfsswtihhioecnrheb,qyuaeMmsaotynegd26iotnohffeorrtmotahxtiiinogcns,oinnnfooatremmsmattoihnoanituoDmnuPPPoFFnOOtAS.

re 3M Specialty Materials SSMCRPCaan,eMrN 551441000 F1-0800- 1378 BM remo tL hs D To fre PfsT g8s SBi] == Dr.

3M Medical Department Study: T-6316.5 3M Medical Department Study: T-6316.5 AnalyticaBl SAtuCdKy: TFOACMT-ATOINX-013 LRN-U2095 Analytical Report: FACT TOX-013 LRN-U2095 Study Title Analytical Study 2(N-Ethylperfluorooctanesu1fonamido)-ethanol in Two Generation Rat Reproduction Amended Analytical Laboratory Report Determination of the Presence and Concentration of PFOS, M556, PFOSAA, and PFOSA in the Liver and PFOS, M556, PFOSAA, PFOSA, and EtFOSE-OH in the Sera of Crl:CD@BR VAF/PIUS@Rats Exposed to EtFOSE-OH Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date MAayt s3ig1n,in2g001 Performing Laboratories Sera Analyses Liver Analyses 3M Environmental Laboratory Building2-3E-09, 935 Bush Avenue St.

fAoraduETI0MAHPRoevRerrLsoRATEDsicRoFRmGiHnTAva Repo cue tame: a oonsve Sumpcotton: caren --a a: serum sn Sartso unt 2m - Sat acon arenes bctonoue: 6reo20s ot Cubs. 17508008 wr: [Ee Aros sdos Tew 242 Lccaumnio Erma 2 somo JS prs oman convo 300 oteracr x Sutoa m prs orsio Cot Vu On Pham: p55 ars Concanatontite: rg cowrovio TrrTTroooeennn Torroonn TTTrrroooann owrreaess wuse ocoec oeraenon asrTeornon H:v oiian [onPoE om dSoms ibsaic on :v F ao wowoeo re ]oowemem =s=Aa seco cowrouno jciivhearodn e us es-me Scoew Bmo oomwe apy erpoomson owne =um 0R0 tRtsry womoimis rmettr_r_ _ awcocrens an 0AXVS ANALYTICAL SERVICES LTE 1r1r iss st se ca5lsrm ssns si [ar------URS ---- 1 ramuS s -- Laan: A318 ann sees Sao cotton Coote: am a on wom --" Soham: eo casas tuGamntnou: vo-- Moon Cane renos 2 ee nos ems sumpnvuate envoy 30 St Skuta. tookie A wore orenaet a0 umn wow 5205 tony cmon wreorn ress eee 3505500 -- wooomr n omoTooes ff=ey == weasocomes mqureesn awe gcoEw oemenon 3y woiai 25w 2 mm==w $.

AR226-2043 To: cc: Subject: Roger J Zipfel/AE/DuPont@DuPorrt.

AR226-2263 ...... . .

AR226-2415 ^^ Y (^f^-^ PENNY, HERE ARB THE RESULTS FOR THB C-8 IH WATER SAMPLES THAT YOU AND TERRY COLLECTED.

FOR DU FONT USE ONLY AR226-2755 Copies co:' E.

FOR bU FONT USE ONLY AR226-2885 Copies to' E.

R226 _ 327 401 AR2A6 - 3219 Duron 5990 TRADE SECRET Study Title H-24768: Subchronic Toxicity 90-Day Gavage Study in Rats `with One-Generation Reproduction Evaluations Volume 1 of 5 LaboratoryProjectID: DuPont-5990 "TesT GUIDELINES: U.S.

HAZLOTON LABCFUCCRiEs APAERICA.

hiss eg BiH iEyi ii i i ib NUR i| bil 1H8l 1 Brzse ek Resi i i lle -- Fe : A | 3 42 i-- 2 HE 3 iiiki '3 felis iiil !

Pimephales Summary.

Name: Chine Sakr, MD MPH ' Robin Leonard, PhD 2 Mark Cullen, MD 1 Program Affiliation: Address: Phone: Fax: Email: `-Yale Occupational and Environmental Medicine Program 2Epidemiology Program at DuPont Haskell Laboratory for Health and Environmental Sciences 135 College Street, 3rd floor New Haven, CT 06510 856-816-1539 203-785-7391 carine.sakr@ yale.edu TITLE Twenty-five year longitudinal study of serum total cholesterol related to a serum biomarker of exposure (serum perfluorooctanoate or PFOA) in a polymer production plant.

AR&AE _ 1250 r -- - ce -------- -- | TSCA NCIC NoTIFICATION FORM FOR CBI DOCUMENTS --_-- DockeTNumBer: ___#R236 DOCUMENT CONTROL NUMBER: _b33 Occco 8D DOCUMENT DATE: 3-31-02% DOCUMENT TYPE: Docft 2& 2ZzBz 2= 3252 &= THEDOCUMENTREFERENCEDABOVEIS CLAIMED AS CONFIDENTIAL BUSINESS INFORMATION `(TOCSFBCITA)S,UCNA ADREIERQN TSUIEIMCRPTEOD ISSOEENSP1CA4RIOTMFOIPTNRAHOLETPTEEOCNXTAILCFTRSIOUESMBSFPTOUARBNLTCIHCEESDKICNSOOCNWLTIORNSOGULRAEANSCDCTWB(IITLSOLCFBAUT)LA.IUNNEATDUHTAUHTNODSREEICRZTEIDON RELEASEORDISCLOOSFUSURCEH INFORMATION.