AR226-2788 C-8 ALTERNATES: MATERNAL AND DEVELOPMENTAL TOXICITY IN THE RAT (PRELIMINARY STUDY, BY GAVAGE) HASKELL LABORATORY REPORT NUMBER 441-84 Copies to: Company Sanitized.

AR226-2863 Material Tested Copies to; E.

REVISED REPORT Copies to; E.

FOR'DU FONT USE ONLY AR226-2886 Copies to E.

Study Sponsor: Issue Date: Document Reference No.: ELFATOCHEM 14-Dec-95 95/SAEK/1372/AMP AR226-3033 Bacterial Growth Inhibition Author(s): A.M.

AR22-6 3295 . ant ARR26 _ 3295 Dupont 13216 -- TRADE SECRET Study Title H-25878: 150 Biocompatibility Testing STUDY MONITOR: Carol Finlay, B.A.

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IVI/,-\ y u MEDICAL LABORATORIES ENT NAME N,iosw EFERRING PHYSICIAN TWMD COLLECTION RECEIVED ()2/02/99 DATE TIME DATE 10:21114 TIME -FATIENT NUMBER 200 FirstStreetSouthwest Rochester,Minnesota 65905 AGE PURCHASE NUMBER REPORT PRINTED 02/27/99 DATE 002 8:32* TIME SPECIMEN INFORMATION BOD-533-171 0 SEX LAS.

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ADVANCE UNEDITED DRAFT p. 1 AR oq a6_ 36/1 DRAFT RISK PROFILE OUTLINE EXECUTIVE SUMMAR Y I INTRODUCTION 1 .1 Chemical Identity of the proposed substance Mention who has made the proposal and when Spell out the specific chemical identity and particular considerations related to that 1 .2 Conclusion of the POP Review Commi tt ee of Annex D information "POP RC has evaluated Annex D (add reference to the meeting and the decision) information and has concluded that . . . " 1 .3 Data source s short overview of the data sources provided by the proposing Party and/or used by the POP RC in Annex D screenin g short overview of data submitted by Parties and observers (NB : a more elaborated summary of the submissions may be provided as a separate POP RC INF document) information on availability of national and international assessment reports ; [1 .4 Summary of available risk informatio n brief summary of the submitted evaluations and other information referred to in Annex E, point f Alternatively, can be summarised in a separate POP RC INF document ] 1 .5 Status of the chemical under international convention s 2 SUMMARY INFORMATION RELEVANT FOR THE RISK PROFILE 2.1 Sources production, trade, stockpiles uses releases to the environment 2 .2 Environmental fate Further elaboration of information referred to in Annex D, paragraphs (b) - (d) ; based on all relevant available information Monitoring data available integrated under the subheading or alternatively dealt with under separate heading "Monitoring data" Could be split in : 2 .2 .1 Persistence 2 .2.2 Bioaccumulatio n 2 .2 .3 Long range environmental transpo rt 000222 p. 2 y 2.3 Exposure Summary of relevant information concerning exposure in local areas (both near the source and in remote areas) Summary of relevant information concerning exposure as a result of LRET Information on bioavailability 2.4 Hazard assessment for endpoints of concer n Further elaboration of information referred to in Annex D, paragraph (e) ; based on all relevant available information Monitoring data on effects include d 3 SYNTHESIS OF THE INFORMATIO N synthesis of the information under chapter 2 tha t focus on information that is leading to the conclusive statement under chapter 4 4 CONCLUDING STATEMEN T Is the chemical likely, as a result of LRET, to lead to significant adverse human health and/or environmental effects, such that global action is warranted Note : No Annexes ; all other data provided as POP RC INF documents Target size not longer than 20 page s 2 000223

Northwest Bioanalytical a Study No.

AR226-2053 !

AR226-2304 Based on RAGS (Superfund) guidance, Exhibit 6-11 Intake (mg/kg-day) =CWxlRxEFxEP BWxAT !

AR226-2589 BEST COPY AVAILABLE ASH027845 WHOLE DOCUMENT EID781125 EID781125 ASH027a46 EID781126 EID781126 -- v m s .. ...rf.

AR226-2651 41 AR226-2651 Verification Study for Air Dispersion Modeling at Fenceline Draft Plan October 2003 Table of Contents I.