AR226-3071 DuPontHL-1997-00261 HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE STATIC, ACUTE 48-HOUR SCREENING TEST OF H-22274 TO Eafi&Bto SHIES PURPOSE: This is a rangefinding study designedto provide an estimate of aquatic toxicity using fixed test concentrations and data measurements at predetermined intervals.

ANALYTICAL ILABORAToRy REPORT ON THE Determinationofthe Presence and Concentration of Perfluorooctanesulfonat(ePFOS) (CAS Number: 2759-39-3) inthe Serum of Sprague-Dawley@' Rats Exposed to Potassium Perfluorooctanesulfonatveia Gavage LaboratoryReport No.

MICROBICS MICROTOXO TEST SUBSTANCE TOXICITY TEST ldentfty:Perfluorooctanoiaccid,ammonium salt;may alsobe referredto as PFOA ammonium salt,Ammonium perfluorooctanoateP,FO, FC-1 16,FC-126, FC-169, or FC-143.

TOXICITYTO AQUATIC PLANTS TEST SUBSTANCE IdentitAy:mixturceontainipnegrfluorooctanesulwfhoincahtmea,y alsobe referredtoas PFOS, FC-95,oras a component ofFC-203. (1Octanesulfoniaccid)(CAS # 2795-39-3).

HAZLETON LAEC)RATORIES AMERC.A.

: 2774 P4aCtohmpoalnyoogfySciAenscesAopcplicaatotnes sintIenrmtaetnranCaortpioaotnoanl e =sr r e-- e ------ -------- -- T-- T ------------ AR226-0149 P(AATNHCIOLLLOAGRYY RSETUPDOYR)T ELECTRON MICROSCOPIC EVALUATION `OF LIVER IN CYNOMOLGUS MONKEYS 2S6U:LWFEONEIKCCAACPISDUPLOETTAOSXSIICUIMTYSASLTTUD(PYFOWSI:TT-H62P9E5)RIFNLCUYONROOOMCOTLAGNUES MONKEYS CLIENT STUDY NUMBER 6329-223 PAI STUDY NUMBER EM 99.76 Prepared by: James B.

AR226-0337 ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: N-Ethylperfiuorooctanesulfonamide; may also be referred to as U1464, EtFOSA, EtPOSA, F-6309, or FX-12. (1Octanesulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-N-ethyl-, CAS # 4151-50-2) Remarks: Material is a white solid.

MELTING POINT TEST SUBSTANCE Identity: NN--eEtthyFlOpSeErfAllucoorhooolctoarneFMs-u3lf4o2n2a.mi(d1oe-tOhcatnaonle;sumfafoynaalmsiodeb,eNr-eeftehryrle-d to as 1,12,2.3.3,4,45,5,6,6,7.7,8.8,8-heptadecafluoro-N-(2-hydroxyethyl)-, CAS #1691-99-2) Remarks: Material is an off-white, waxy solid of uncharacterized purity.

AR 226 _ 088I ACUTE TOXICITY TO FISH (FATHEAD MINNOW) IEST~ S ~U ~ BSTANC0 G 0E 00 Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-787 or FC787X. (1-Octanesulfonic acid) (CAS # 2795-39-3).

AR226-1990 s ^ ^ ^ i ^ (A ; 0 c ...

AR226-2038 "Roger J.

AR226-2081 WASHINGTON WORKS INDUSTRIAL HYGIENE REPORT PROM l-Jan-1994 TO l-May-1995 3-May-1995 Page 1 AREA: FLUOROCARBONS - HOMOPOLYMERS CHBMICAIi SAMPLE LOCATION *:CONTROL C-8/FC-143 003 FINE POWDER PACKOUT ROOM DATE: 27-Jan-1994 NOTEBOOK; TTF01.P398 DURATION: 370 COMC: <.03 MPB SAMPLE TYPE: P PERCENTAGE: 5% EMPLOYEE #04500 PERS CODE: 08PJ C-8/FC-143 008 P/S - FINE POWDER PACKOUT DATB: 27->Tan-1994 NOTEBOOK; TTF01,P399 DURATION: 375 SAMPLE TYPE: A CONC: <.03 MPB PERCENTAGE: 5% EMPLOYEE #00000 PERS CODE; C-8/PC-143 008 P/S - FINE POWDER PACKOUT DATE: 25-Aug-1994 NOTEBOOK; TTF01,P428 DURATION: 390 CONC: <.03 MPB SAMPLE TYPE: P PERCENTAGE: 5% EMPLOYEE #04632 PERS CODE; 08PJ C-8/FC-143 008 P/S - PINE POWDER PACKOUT DATE: 8-Mar-1995 NOTEBOOK: TTF01.P454 DURATION: 405 COMC: 0.02 MPB SAMPLE TYPE; P PERCENTAGE: 4% EMPLOYEE #04632 PERS CODE: 08P C-8/FC-143 008 P/S - FINE POWDER PACKOUT DATE: 8-Mar-1995 NOTEBOOK: TTFOl,P454 DURATION: 405 CONC: 0.02 MPB SAMPLE TYPE: P PERCENTAGE; 4% EMPLOYEE #04632 PERS CODE: 08PJ C-8/FC-143 017 ROOF AREA-GENERAL DATE: 28-Jan-1994 NOTEBOOK: TTF01,P404 DURATION: 380 CONC: <.03 MPB SAMPLE TYPE: A PERCENTAGE; 5% EMPLOYEE #00000 PERS CODE; C-8/PC-143 031 INSIDE P.P.

H-24921: Dermal Sensitizatfon Test - Buehler Method AR226-2804 DuPont-7977 TRADE SECRET STUDY TITLE H-24921: Dermal Sensitization Test - Buehler Method LABORATORY PROJECT IDENTIFICATION DuPont-7977 PSL Study Number 11321 Work Request Numbet----^J Service Code Numberfatf) DATA REQUIREMENT U.S.

FOR DU FONT USE ONLY Skin IrritaKw AR226-2946 Du Font HLR 112*90 In Rabbits Study Completed On March 5, 1990 PerformingLaboratory Haskell LEa. bIo.radtouryPofm|si r dTe oNxeicmooluorgsy anandd CIofmldpuansyt,riaInl cM. edicine Elkt w Road, P.

FOR DU FONT USE ONLY AR226-2969 Du Font HLR 802-91 gtudy Title Skin Irritation Test vith----------in Rabbits Author John V.