Corporate Toxicology Study Outline July, 1998 ARIG-0227T To Title: FC-129 Preliminary ADME Screen in Rats `Timeline: In Life Start Date: 7/13/98 In Life End Date: 7/17/98 `Purpose: This study is designed to `provide preliminary information on theabsorption, distribution, metabolism and excretion (ADME) of FC-129.

ARBRE _ 124-0 DRAPT REPORT WASHINGTON, WDOROYD RCUONUNCTRYE,EKWEST VIRGINIA NOVEMBER 1997 5TE RY --T_---T-- I =SZZo33n3% E3z8< PREPARED BY: EnvMiarroknmD.entSaplrenRgeesrp,onsPeh.DT.eam ap U.S.

FINAL REPORT PROTOCOL 418-015.

AR226-2039 INTEROFFICE MEMORANDUM Date: Prom: 21-Sep-1998 12:30pm EDT JACK OFFENBERGER OFFEMBJL Dept: Tel No: COPOLYMERS B-180T 863-4959 TO: 4 addressees CC; 5 addressees Subject: C-8 I have made charts showing the C-8 sample results for the past five years.

AR226-2441 TO: Rik Brandenburg INTEROFFICE MEMORANDUM Date: Froy: Dept: Tel No; 20-Mar-1997 14;42 C.de Heer HEERC RSD Lab Hoofdgebouw 31-786301944 ( BRANDERA ) Subject; C8 in P27-1047 dispersie Rik, voor het dispersie monster P27-1047 uit de U.S.A. heb ik de volgende CS-gehaltes gevonden: Hethyleenblauw methode: C8 = 998 en 999 ppm ' GC-methode: C8 = 955, 900 en 1041 ppm jij Zoals je ziet in beide gevallen veel hoger dan de U.S.A.

AR226-2960 DU FONT USE ONLY Du Font HLR 457-91 Study Title STATIC, ACUTE, 48- AND 64-HOUR EC50 O^II^JUr10 Paphnia aagna Data Requirement Organisation tor Economic Co-Operation and DevelopfBent (OECD) GuiHeifne for' festTng ChemicaTsY 2'02' Author Kevin N.

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AR226-3126 TRADE SECRET Study Title H-24119: Bacterial Reverse Mutation Test in Salmonella typhimurium and Escherichia coli Laboratory Project ID: DuPont-3220 TEST GUIDELINES: U.S.

I FINAL REPORT PROTOCOL 418-011 ORAL (GAVAGE) DEVELOPMENTAL TOXICITY STUDY OF N-ETFOSE IN RATS SPONSOR'S STUDY NUMBER: T-6316.7 FINAL REPORT DATE: 17 DECEMBER 1998 PROTOCOL 418-011 ORAL (GAVAGE) DEVELOPMENTAL TOXICITY STUDY OF N-ETFOSE IN RATS SPONSOR'S STUDY NUMBER: T-6316.7 TABLE OF CONTENTS SUB-JECT 1.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonawtheich may also be referredtoas PFOS, FC-95, or as a component ofFC-201 F.

CORNINGHazleton MUTAGENICITY TEST ON T6358 MEASURRNG CHROMOSOMAL ABERRATIONS IN CHINESE HAMSTER OVARY (CHO) CELLS FRNAL REPORT AUTHOR Hemalatha Murli,Ph.D.

FINAL REPORT PROTOCOL 418-008 PERCIONMABTIANLE/DPOOSRTANLAT(AGLAVRAEGPER)OFDEURCTITLIIOTYN,TDOEXIVCEILTOYPSMTEUNDTYALOFANPDFOS INRATS SPONSOR'S STUDY NUMBER: 6295.9 FINAL REPORT DATE: 10 JUNE 1999 50133 PROTOCOL 418-008 COMBINED ORAL (GAVAGE) FERTILITY, DEVELOPMENTAL AND PERINATAL/POSTNATAL REPRODUCTION TOXICITY STUDY OF PFOS IN RATS SPONSOR'S STUDY NUMBER: 6295.9 TABLE OF CONTENTS SUBJECT I.

AR226 -- 0755 ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity: A mixture containing perfiuorooctanesulfonate, which may also be OrecftearnreesdutlofoansicPaFcOiSd), (FCCA-9S5#, 2o7r9a5s-3a9-c3o)m.ponent of FC-203CE. "- Remarks: The 203CE (2/21/89). 3M production lot numberwas Current information indicates 519. itis a The test sampl mixture of 1.84% is FC- fPoFaOmSer,,330.%1%diseotdhiyluemneocgtlyylcsoullfbauttey,l 2e.t1he9r%,p6o0l.yo2x3y%etwhaytleern,e2m.o5n6o%ocStuylltpohneenyl 2et1h4erw,a0s.a1d2d%esdodaitaumnloamuirnylalsuclofnatcee,ntarnadti0o.no05f%2t0o0lylmtrgia.zole.

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