It is known that some substances in our environment; for example; 2-naphthylamine and tetraethyl lead are converted to carcinogenic compounds.

Another matter I might call to your attention is the fact that the finding of some lead in the urine of the claimant by Mayo's was several years, at least two or three after he was employed.

Kehoe: You are acquainted, I understand, with the fact that the Dow Chemical Company is using tetraethyl lead in a chemical process.

Devan purporting to relate to the additional b-th cc. of tetraethyl lead per U.C. gallon that has recently had the approval of the U.S. burgeon General.

Tetraetilo de Mexico - (49 per cent Du Pont) - manufac tures and sells tetraethyl lead.

.*';' \j'S' *' `r-'t "" " Thermopoile,;in Hoi Spring County, Wyoming,'while- in the emp&oy 'of 'the Town of Thermopolis,*'Wyoming j"';that'oiaim 'has been p**l'or'' compensation on account of such injury; that such injury was hot caused by the"culpable, negligenceof said employee, and that said injury is described as follows: The loss of vision of both eyes, resulting in a permanent partial disability to said employee, of 95^;; that said disability in the loss Of the sight of both eyes was the result of the use of tetraethyl leaded gasoline by said ' '" ;

Lead arsenate ......................................

39--Chemical Hazards hydroxytoluenes cresols monomethyl aniline methyl aniline 2-hydroxytnethylamine diethylamino ethanol motor fuel antiknock compound tetraethyl lead iso-butyl carbinol iso-propanol iso-propyl benzene iso-propyl carbinal 1 1k muriatic acid hydrochlonc acid munatic ether ethyl chlonde l-amyl alcohol N iso-propyl alcohol cumene naphtha 76 naphtha (petroleum) 1-butanol nitrating acid acids, mixed nitrochlorobenzene chloronitrobenzene 0 ilgroin liquefied petroleum gas LOX lye M naphtha (petroleum) LP-gas oxygen, liquid sodium hydroxide oil, fuel oil of mirbane oil of vitriol pr fuel oil nitrobenzene sulfuric acid pentanol acetate MBK methyl butyl ketone pentanols MDI isocyanates 2-pentanone MEK methyl ethyl ketone perchloroethylene methanal formaldehyde petroleum ether methanethiol methyl mercaptan phenyl amine methanol methyl alcohol phenyl chlonde 3-methoxy-1 -butanol amyl alcohols phenyl ethane 2-methoxy ethanol phenyl ethylene ethylene glycol monomethyl ether phenyl methane methyl Cellosolve acetate 2-phenyl propane ethylene glycol monomethyl ether acetate phorone, iso methyl acetic ester methylacetpaitme etic ketone methyl acetylene propyne polonium amyl acetate amyl alcohols methvl propyl ketone tetrachloroethv lene naphtha (petroleum) aniline chlorobenzene ethylbenzene styrene monomer toluene cumene isophorone cyclohexanone radon methyl acrylate methyl benzene 2-methyl butane 3-methyl-1-butanol 3-methyl-1-butanol acetate 2-methyl butyl ethanoate acrylate,metphryolpane toluene 1,2-propanediol pentane 1,2,3-propane tnol l-amylalcophroolpanols amylacet2a-tperopanone amylacetpartoepene oxide LP-gas propylene glycol glycenne propyl alcohols acetone propylene oxide methvl n-butyl methane hexane 2-propen-l-ol allyl alcohol methyl Cellosolve propyl acetone methyl butvl ketone ethylene glvcol monomethyl ether propyl carbinol butanol methyl Cellosolve acetate propylene dichlonde 1,2-dichloropropane ethylene glycol monomethyl ether acetate propyl methanol butanol methyl chlonde methylene chlonde pnissic acid hvdrocvamc acid methyl cyanide methylenebis (4-phenyl isocyanate) acetonitrile isocyanates Q methvlene chlorobromidebromochloromethane quick lime lime (quick) methvlene dimethyl ether methylal R methvl ethyl carbinol methvl ethylene glycol 2-methvl hexane methyl iso-butyl carbinol butanol propvlene glycol heptane methvl amyl alcohol red fuming nitric acid refrigerants mtnc acid (red fuming) see chemical name c9 methyl methacrylate acrylate, methyl methvl methanoate methyl formate 4-methvl-2-pentanol methyl aim 1 alcohol 4-methyl-2-pentanone methyl iso-butyl ketone 4-methyl-3-pentene-2-one mesitvl oxide sodium evanide sodium pentachlorophenate sulfuric ether Ti cyanides pentachlorophenol ethsl ether methvlphenols eresols TDI isocyanates methyl propanol butanol Teflon poK'tetrafluoroeths lene mineral spirits naphtha (petroleum) TEL tetraethyl lead monochlorobenzene chlorobenzene tetrabromoethane acetylene tetrabromide monoethanolamine ethanolamine tetrachloromethane carbon tetrachloride monoethyl amine ethvlamine tetrahvdronaphthalene Tetralin monomethyl hydrazine methyl hydrazine tetramethylene oxide tetrahydrofuran 1210

Machle on tetraethyl lead since he will find there a,rather complete description of the methods of treatment which we are using at the present time, and with fairly good results.

Devan purporting to relate to the additional 4th cc. of tetraethyl lead per U.D. gallon that has recently had the approval of the U.3.

Tetraethyl lead poisoning in its worst form gives an acute encephalopathy.

D RAK:ss Meth - Methods for Determining Lead in Air and in Biological Materials On the Toxicity of Tetraethyl Lead and Inorganic Lead Salts by R.A.K.

N29574 11 Data and Correspondence Sludge, Scale and f'ater Bottoms -s from Gasoline Storage Tanks oo CO 02 o Ur Required: March 4 I9I4B Determination of lead compounds present Results Per Cent Per Cent Lead as Lead as Lead Tetraethyl Triethyl Lead <0.00001 O.OOO3 Per Cent Lead as Diethyl Lead Halides Q.OOI7 Per Cent Lead as Di- and TriethylLead Halides and Carbonates 0*00045 Per Cent Lead as Inorganic Lead 0.225 Reported: 3-24-48 0009888 SUBJECT Standard Oil Company - Steel EL Segundo, California DATE April 23, 1948 I regret very much not having answered your letter of March 31st sooner, regarding scale from side plates of a gasoline tank which you analyzed.

Gallon 2.46 ccs of T.M.L. per Imperial Gallon /2 2 < We enclose copy of this letter so that - ou if you wish forward it to Petroleum Section* ' there be any additional information which they rucuro#no t orT'^ you will Jet us hnowr. *' In reply to the last paragraph of your letter r-o confirm that the anti-knock compounds contained in Tetraethyl Load and anti-knock compounds contained in TetraMethyl Lead are the only anti-knock agents which w/c- currently supply* Tours very truly.

Thl3 is no surprise to me, and it will not surprise you, but it is of some con sequence to recognize that, following the absorption of significant quantities of tetraethyl lead from any source, or over any length of time, the concentration of lead in the blood undergoes little or no change, while the urinary lead concentration goes to high levels which vary with the severity of the exposure.