AR226-3176 DuPont-6011 TRADE SECRET Study Title H-24516: Influence on Growth and Growth Rate of the Green Alga Selenastrum capricomutum Laboratory Project ID: DuPont-6011 AUTHOR: Terry Lee Sloman, B.S.

AR226-3192 DuPont-6541 TRADE SECRET Study Title H-24951: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Laboratory Project ID: DuPont-6541 AUTHOR; Carol Finlay, B.A.

Bausch + Lomb PFAS Statement September 2023 Executive Summary: Bausch + Lomb is one of the world's largest suppliers of contact lenses, lens care products, eye health pharmaceuticals, intraocular lenses, and other eye surgery products.

AR22C = 327] " -_-- --~ TRADE SECRET #Razg -- 327/ DoDuwPonnte11604 Study Tite H-25435: InflAulegnaceSoenleGnraoswtrtuhmacnadprGircoowrtnhuRtaumteofthe Green Laboratory Project ID: DuPont-11604 TEST GUIDELINES: OSeEctCiDonG2u:idEeflfiencetsfoonr TBeisottiincgSCyhsetmeimcs,alNsumber 201 (1984) ~~ Commission Directive 92/69/EEC EEC Method C3 (1992) AUTHOR: TerryLee Sloman, B.S.

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389 20109 NEW C HE MIC AL M AT ERI ALS Vol 38 No9 75 710065 Progress in synthesis and applications of trifluoropropanoic acid Zeng JijunDu YongmeiZhang WeiKang Jianpin Hao ZhijunWang BoMa YangboLv Jian Xi'an Modern Chemist ry Research InstiuteXi'an 710065 AbstractPhysical and chemical properties of trifluoropropanoic acid w ere introducedDifferent preparation meth- ods and application progress in some fields such as synthesis of fluorinated compoundscatalysts and specific solvent w ere s um m ariz ed Key wordstrifluoropropanoic acidpropertypreparationapplication Oxone2K HS O5K2S O4K HS O4 5 1 1 CF3 1 RhC 2 CF3 3 4 2 CF3S O2ClCF3CdBr 333- -1- HCFC-1233zd 21 CF3SO2Cl AIBN CF3S O2Cl 333--1- 1984 ODS 76 38 25 HCFC-1233zd HCFC-1233zd 1 HCFC-1233zd 9 5 2HCFC-1233zd 10 6 3HCFC-1233zd Oxone 11 7 26 111333- CF3C H2CCl3 CF3C H2CCl2F CF3C H2CClF2 OleumS O3 H2S O4 12 8 3 31 CF3 311 2-13 2- 312 B1 B1 14 3 N- B1 B1 B1 313 U S5100751 15 32 16 17 33 18 19 4 20 HCFC- 115 9 115 15 6 T gT d 1 Cassidy P ET hermally stable polymers M New YorkDekker 1980 2 Yang H H Aromatic high-st rengt h fibers M New York Wiley 1989 3 Sheng-Huei HsiaoYu-Hui ChangNew soluble aromatic polyamides containing et her linkages and laterally attached p-terphenyls J European Polymer Journal2004401749-1757 4 M 1988 5 Lora JSoriaro BComposite membranes of aromatic polyamidemembrane peaparation and characterization J Deaolinut io n 198764375-386 6 Biw are M V Ghatge N DSt udies in piperazine containing poly sulphone-amides for use in w ater desalination J Desalinat io n 199510193-100 7 Iborra M LLora JEffect of oxidation agent s on reverse osmosis membrane performance to brackish w ater desalination J Desalination199610883-89 8 Wing-Hong ChanSuei YeeSynt hesis and characterization of random polyamide-sulfonamides3Copolymers f rom t w o diamino monomers J Polymer199533234503-4508 2010-06-12 2010-07-18 76 1233zd HCFC-1233zd 1 Henne A L Fox C J Ionization constant s of fluorinated acids J J Am Chem Soc1951732323-2325 2 Buyle O Lorent K Mat hieu V Process for t he manufact ure of fluorinated alcohols P EP1820789A12007-8-22 3 How ard M PLeonard O RRobert L SMarion E HImproved synt heses of et hyl 333-t rifluoropropionate and 333t rifluoropropionic acid J J Chem Eng Data197116 3 376-377 4 Ling XiaoT omoya Kitaz umeSynt hesis of some fluorinated acidsketones and alcohols derived f rom333-t rifluoropropionic acid J J Fluorine Chem19978699-104 5 Wakselman CT ordeux MSynt hesis of 333-t rifluoropropionic and 444-t rifluoro-2-ketobutyric acids J J Fluorine C hem 19922199-106 6 Bouillon J PMaliverney CMernyi RT rifluoromet hylation of aliphatic halogen compounds J J Chem Soc Perkin T rans199192147-2149 7 Munavalli E SLewis OMuller A JNovel reactions of perfluoro-2-t rifluoromet hyl-propene J J Fluorine Chem1993 63253-64 8 Yamanaka H T T akekaw a KMorita T IPreparation of novel -t rifluoromet hyl vinamidinium salt and it s synt hetic application to t rifluoromet hylated heterocycles J T et rahedron Lett 1996371829-1832 9 Komata T Akiba SHosoi KOgura KConvenient synt hesis of 333-t rifluoropropanoic acid by hydrolytic oxidation of 33 3-t rifluoropropanal dimet hyl acetal J J Fluorine Chem 200812935-39 10Komata T Akiba SHosoi KOgura KProcess for producing 333-t rifluoropropanoic acid P WO 2007052492A1200705-10 11 Van Der Puy MT henappan APreparation of fluoroalkyl compounds and t heir derivatives P U S 57771841998-06-07 12Veronique MOlivier BF rancine JPreparation of carboxylic acids P EP 1754697A12007-02-21 13Jimenze J MBemis GWang T ianshengKinase Inhibitors P WO 2008094992 A22008-08-07 14Wood M RAnt hony N JBock M GN-Biphenylmet hyl aminocycloalkanecarboxamide dernatives wit h a substit uent on t he met hyl usef ul as brad ykinin antagonist s P WO 2003066577 2003-08-14 15Kato EIshii KIshibashi HLiquid developing agent for elect rostatic photography P U S 51007511992-04-31 16 P C N 1012742262008-10-01 17 F P C N 17576392006-04-12 18 Yamamoto EIshihama Y Asakaw a N LC-MS analytical met hod and it s mobile phase P JP 20040772762004-03-11 19 Spaugh A T Vinyl ends measuring met hod P WO 20080974162008-04-16 20 J 200432944-46 2010-04-19 2010-06-03

Risicoschatting emissie PFOA voor omwonenden Locatie: DuPont/Chemours, Dordrecht, Nederland RIVM Briefrapport 2016-0049 M.J.

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Risk assessment of exposure to PFAS through food and drinking water in the Netherlands RIVM report 2023-0011 Risk assessment of exposure to PFAS through food and drinking water in the Netherlands RIVM report 2023-0011 RIVM report 2023-0011 Colophon RIVM 2023 Parts of this publication may be reproduced, provided acknowledgement is given to the: National Institute for Public Health and the Environment, and the title and year of publication are cited.

Apr 25, 2023 Comment on Proposed Restriction of PFAS Conference of Fluoro-Chemical Product Japan (FCJ) On behalf of chemical manufacturers, we, Conference of Fluoro-Chemical Product Japan (FCJ), have been working tirelessly to comply with national chemical regulations.

PFOS: Determinationofthe n-Octanol/WaterPartition Coefficienbty theShake FlaskMethod - A Non-GLP FeasibilitSytudy inSupport ofWildlifeInternationaLlt,d.

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BIODEGRADATION TEST SUBSTANCE Identity:N-ethylperfluorooctanseulfonamidoethanolm;ay alsobe referredtoas N-ETFOSE Alcoholor FM-3422. (1-Octanesulfonamide,N-ethyl- 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-(2-hydroxyethyl)-, CAS # 1691-99-2) Remarks: Materialisan off-whitew,axy solidofuncharacterizepdurityThe followingsummary includesa historyofstudies.

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Experiment No.: Conducted At: Dates Conducted: Conducted By: Reviewed By: Acute ocular Irritation Test with T-3493 in Albino Rabbits 0884EB0008 Safety Evaluation Laboratory Piker Laboratories, Inc.