Document jgYw8GjrVYko6z3xwVX7w0QgQ

A = Minnesota Pollution CAognetrnocly Contents Contents Table 1 ...................... 2 ther evaluation 3 Further evaluation ..... 3 Celeuling LOS... 3 Calculating LD50 ....... 3 Appingknowiodgo 3 Applying knowledge .. 3 Sufficient knowledge Sufficient knowledge unavalabi.......3 unavailable ............. 3 Publanod momaions Published information 4 Tae? Table 2 ...................... 4 MoreAlomo-- ... 4 More information ....... 4 TThhee LLeetthhaalliittyy CChhaarraaccteterriissttiicc AA MMiinnnneessootata--ssppeecicfifiicc hhaazzaarrddoouuss--wwaassttee cchhaarraacctteerriissttiicc TT VWiaa tstoelHz azardu ousWWad assttee1o #22.0055u MMaayys 22000089. tCehathalriaatlciy.tt.ye,riaashthiaaczzasarrddpoouuess wwcaoasstMitieenfnesiotca, Lpoisonocccuoohsnna,srsaiiedcdleteeerrcrsitstththoieecftt4soopxwieaicccslitoofelig.coigtcMoiacilaMn,ln,ienoosnrroetsaota, poisonous, effect era waste. Minnesota aaanssi:maarrla.attiooMewwiditithhantthhceeibbaoolddyydowwseeeiiggihhntftooorffmttahhteeion is eaadnnteditemerrtmamelit.innMieemddeadtflbiao.rnraaTlesshtppheeaecLlicfdietocsteeexxapipnoofssouurrmreeammtieoetnthhooisdd and test animal. The Lethality roe asimamaeal, ils waste generators must ensure that wastes uc suedfor he Lethal and nhlation exposure methods. The are evaluated for the Lethality Charaewetllarfsortthe fiedeeral median lethal dos or the nbalation characteristic as well as tbr the federal characoftneirbiilys,Otxiidiczssrs, expoisscoummronely refo0rasetdhe characteristics ofIgnitability, Oxidizers, Cori.Reactivity, and Tovicity medianlethal concentration (LCS). Corrosivity, Reactivity, and Toxicity. Whthemiore fuwlar characteris 5 of er Minnesota Rules. a waste While file more familiar characteristic of Tos lo mans he ot woes Under Manso Rules avast Toxici~ also contains the root 'toxic,' that chen te prnad (EIST characteristic refers to the presence and Soncenttioonf ecific oie a concentration of specific toxic oamiacndetaermninedtby she Ws yore blkniry contaminants as determined by the Tovey Characters Leaching Procedure +anoral LD. (a) es than $00 Toxicity Characteristic Leaching Procedure (TCLP) The Lothalit chasccrisic i+ milligramsperkilogram (nek) (TCLP). Thc Lcthalib" characteristic is concerned wilh the overall toxicological + a dermal LD. (rabbi) es han concerned with the overall toxicological effof the waa dsetetrmiened by Tooomghg effect ofthe waste as determined by biological esting In this document, wastes, rE el biological testing. In this document, wastes playing th Leth chassivss illgpnrcmubeic mtr (nem) displaying the Lethality characteristic arc tomed Leal Torduasndtmisss termed 'Lethal.' Selma isean an inhalation LCS0 (rat) les than 1000 Seek ways to reduce the total amount of wayousgenteratean the oct of ts per million (pp)for inesand waste you generate and the toxicity ofthe products vou use toreduc the mountof Tose pom fore products you use to reduce the amount of potently lethal hazardous wastes you potentially lethal hazardous wastes you ent To Fes ane cont he Evaluatingforlathality generate. For free assistance, contact the oncsora Technical Asssance Program ope: 18 (OF IMIR Minnesota Technical Assistmlce Program (UATAPy Cones lomion pu 4. opp soutien forthe (MnTAP). Contact information on page 4. For more informationn the federal Pollution Carrol Agency (MPCA) has For more intbrmation on the federal charctenstcs, soc MPCA hazardouswaste compda ltof abuts that indicate characteristics, see MPCA hazardous waste Factsheet 4204, Charccterisic Warts, waste may be Lethal Sec Table | fact sheet ~2.04, Characteristic Wastes, pales cain `ou may conswasiteddocseiormeast available at wwpasate mnus publication th Lethalitychamctwheensyotucian www.pca,stateran.us/publications/ 2p cmon the docs om nh th w-hw2-04.pdf characteristic considers the oral, dermal, and inhalation exposure methods. The median lethal dose tbr the inhalation exposure is commonly rcfcrred to as the median lethal concentration (LC50). Under Minnesota Rules, a waste is hazardous for the Lethality characteristic ~vhcn a representative sample of the waste exhibits any of the following: an oral LD~ (rat) less than 500 milligrams per kilogram (mg/kg) a dermal LD~0 (rabbit) less than 1000mg/kg an inhalation LC50 (rat) less than 2000 milligrams per cubic meter (mg/m3) for dusts and mists an inhalation LCS0 (rat) less than 1000 parts per million (ppm) for gases and vapors Evaluating for lethality To help you evaluate waste for the Lethality characteristic, the Minnesota Pollution Control Agency (MPCA) has compiled a list of attributes that indicate a waste may be Lethal. See Table 1. You may consider a waste does not meet the Lethality characteristic when you can document that the product from which the "LLTeehtethhtaoalslicittoyylottghihcrraeelsschhcoolclddsosf a material is oToTffhetteeelnntommdxeoieacsasoesuluo(rrgeeLiddcDaiinl.n ettewffrhemeiccstohmoofffitsatshhdmeeeammateeemdrdiioaiaalunninsof pmlaeoamtpthuaealtlraeidtriaioaolslnewwo(hLhifciDachshs0pw)wei,cliwilllfhikilccillhalmahimsaaltlffh,eofaapaameteroessuscttnet dof population of a specific animal, presented waste is generated does not display any of eTms Mama the Table 1 attributes. Maintain documenatiosnt he generation sic documentation at the generation site. 173 product docs display aay ofthe Ira product does display an)" of the abhu ewasttemaysbeL, eal,you attributes, the waste may be Lethal; you 4st value i Fre, Manage vast st must evaluate it further. Manage waste that NEO w-hw2-05 eons3p0o0n 0 Cort 57pRye TST20E5a 1262S 5B1O0.36P57d230E06 SAvSe Shere=fms Minnesota Pollution Control Agency 520 Lafayette Rd. N., St. Paul, MN 55155-4194 o www.pca.state.mn.us 651-296-6300 800-657-3864 TTY651-282-5332 or800-657-3864 Available in alternative formats Ex3h3i3b2it 33333322..00000011 STATE 02770359 STATE_02770359 playny of he abe na Lely charac | displays any of the attributes as a Lethality characteristic roswit re and on not Tor | hazardous waste unless and until you evaluate further rion RTO C151 Subs addemon hat | under Minn. R. 7045.0131, Subp. 6 and demonstrate that a ors ply oe eng chron the waste does not display the Lethality characteristic. Instead ofpertorming l alo, you may shes Instead ofperforming a full evaluation, you may choose 1 sn ha eanl d ma Fl to assume a waste is lethal and manage it as fully ocd bdaoe regulated hazardous waste Table1: Atibouf ptoteentisal aha Table 1: Attributes of potential lethality A drug requis yh MinesaSoa of Pharmacy A druq* regulated by the Minnesota Board of Pharmacy A pesticide equ y he Mista eparment of Aicatne A pesticide regulated by the Minnesota Depa[tment of Agriculture A polsoneus material equi oranspoby he U's. Deparment of Tansoraton A poisonous material regulated for transport by the U.S. Department of Transportation A taal bering anya odes signal as Poin, Poisonous', Toi" Lava, Fatal or Dendy" A material bearing any of the descriptive or signal terms "Poison", "Poisonous", "Toxic", "Lethal", "Fatal" or "Deadly" Piglet dbiekvogiirotpbrib penny on the product shipping container, product label, or in product documentation + A teal bearing the shu and rossbanes regi A material bearing the 'skull and crossbones' graphic i botkier of on the product shipping container, product label, or in oteamnion product documentation ean4US. Departof Tansortaion p A material bearing a U.S. Department of Transportatiou Smee Oe & "Hazard Class 6.1" label or placard on the product e Coag rato ot 8 mr Cay roe Cmts shipping container, product label, or in product dodcoucmuemnetnattaitioonn N/ N<7 Ne A ate bearinga Naat Fv Ring (NFR) A material bearing a National Fire Rating (NFR), mmHa cosa Syn FR of Hazardous Materials Identification System (HMIS), or tart: teal encommnomaton Gods 2 Hazardous Material Identification/Information Guide ((HHMMIIGG)) rraattiinngg HHeeaalltthh DDiivviissiioonn 2_>33oorr SSppeecciiaall HHaazzaarrdd ~ pol SivHEoR nynape-tonheppecsoavlppos Division "POI" (NFR only) label on the product shipping ti, pote mo sot eamotai = EET] container, product label, or in product documentation A otal boing Lo data ana Mater Safty Dota Sheet QSOS) which 2 av, of wl you re routed A material bearing LDso data on a Material Safety Data Sheet (MSDS) which you have, or which you are required by erm we sos et a on poo os on bares oh OSHA regulations to have, which states that the LDso of any of the ingredients is less than the lethality thresholds on a ota ts et page 1 of this fact sheet A teal hig specific formation ktowns yo at he wae may easly Lothl,rlvdng tt A material having specific information known to you that the waste may reasonably be Lethal, including but not ae roa BatoPoca Toy Oka OME peTwA he Soe 1 SO oy oh abv limited to information that your processes may alter a product or other material which does not exhibit any of the above a ooh ae meas sory messmo bo Lor attributes in such a way that the waste generated may reasonably be Lethal A tera vig specific formation publishby th HPCA i Ta2l. ie fot shot hthwatemay A material having specific information published by the MPCA in Table 2 of this fact sheet that the waste may emotLoe reasonably be Lethal Wastes ich tay 1 ates ma bocarsdred nr Lota Wastes which display no attributes may be considered non-Lethal. te wc feta bome aes x 9 ema dustbe vated rer, Wastes which display one or more attributes may be Lethal and must be evaluated further. Fy -- *A 'drug' as specified in Table 1 above is considered by the MPCA to be a 'pharmaceutical' eligible for further evaluation oe anger on prove tim ot otMeo. Evils Pramas ois oo Ll for lethality under an approved Petition for the "Alternate Method to Evaluate Pharmaceutical Waste for the Lethality acne fou poe oh 1 apo Pekon. ofmov aon on ine Meld: oeMCA. Characteristic" if you have such an approved Petition. For more information on the Alternate Method, see MPCA Retinwas Ts hoo $445.Art eth EvilsramasouiHcoass os he Loa Croan, hazardous waste fact sheet #4.45b, Alternate Method to Evaluate Pharmaceutical Waste for the Lethality Characteristic, ee es te pm ms available at www.pca.state.mn.us/publications/w-hw4-45b.pdf TheLaat The Lethality Chaecase Characteristic + WastsWiastae z2.0a5 -rLMeouy20s09 Waste/Hazardous Waste #2.05 May 2009 page 2 33333322..00000022 EI F Sma stare 02770360 STATE_02770360 Further evaluation for lethality Applying specific knowledge to dstermine Further evaluation for lethality Further valuation ofa wast for the Laas the lethality of a waste Further evaluation ofa waste for the Lethality charactcnstic may include calculating csumated LD, | Asa almtive to cling th simsd LD. ofa characteristic may include calculating the estimated LDso oth wast aapphing spoific nd documented asc. vou may ppl pes nd dcumcrid ofthe waste or applying specific and documented Knowiedes ofmateraalsd processes vied n the Knowiodgs ofthemach snd processes wid n knowledge ofmaterials and processes used in the aencrion ofthe waste fon crate the waste her | gern th wast. he waste sam are generation ofthe waste. If you evaluate the x~aste further aanndd ccaann ddeemmoonsntsrtraattee tthhaatt iitt ddoocess nnoott mmeeett tthhee LLeetthhaalliittyy Chracrtiaso dented Mim RTS 0151, Subp. | product woud essonabs meft Loli characteristic as identified in Minn. R. 7045.0131, Subp. vou may manage the waste a non-Lthlt Shamanic when disposed of Cruficaions ox 6, you may lnanage the waste as non-Lethality Chace wihout Father acon 0 Sourpart informed samentbsy a rodvel anaaches #3 Note: A wast ti not bands uc th Lethality characteristic without further action on your part. Nole: A waste tlmt is nol lmzardous due to the Lethality Ber nb mans or mammals may constitu now ht the characteristic lnay be hazardous for other reasons. Always Pea Sor an ates rasonalynom hl. perform a complete evaluation. Calculating the estimated LD of a waste ut ane unableto caur he cutR mated LD-- of he Calculating the estimated LDs0 of a waste To calelt he cstimatod LD. of a wast, you must ast, vou may ll be abl 0 th valle dota to To calculatc thc cstimatcd LD~0 of a waste, you must in tn appropiate LD dota forallofhs wile ulate he wast forthe Lethal chants ASan have the appropriate LD5o data for all ~f the waste Component th essonaly may PGCE 810KSCTct. | cxample he onl LD dota ou ars ab Joc fs. components that reasonably ma~ produce a toxic effect. TheLD. dota you se must befo th comctoxporre | fora cups method she ha hon 0 ae The LD~0 data you use must be for the correct exposure method and et animal. You may elude Ingen conideng or Fh estan fret tan method and test animal. You may exclude ingredients in essonbly will notproadbuaacl oelogial | required nena or th xpos metho yon ne that reasonably will not produce a ham~ful toxicological Tet I you erence matcnal Ses Tang for 06% | considering. tou may app accoped principles of effect. If your reference nraterial gives a range for the % Conceration ofan mgr, yout vs he iochemist,tvicoogsand physiology fo he LD: concentration of an ingredient, you must use the win ton stan daa vou dba to deerme whether he asic vould Note: Ingrdicns identifi as"ner"on product labels, maximum range value in your calculation. Note: Ingredients identified as 'inert' on product labels, Sucha propellants sevens nd armors, may nt oe a ------ such as propellants, solvents, and carriers, may not be Seeders ea nego ov aspeile web gerne ae Sachs he US assumed to produce no harmfid toxicological effect. Ni produ abts demi hes ingronts snc | Food am Dg Admmarton (FD. U. Emironmenis Many product labels identify these ingredients as ~inert' Sclhy as pbeceautseroleudmobnaosdtpservfort,i mheayahnoSsingonfcoanft | | SarPsescmonooefAsngeeesenss(hePbAeaytuor pnevdrsctabmyssasrnFaLdeoaldowrhen he pros Hoveesmanyofthe geadians. only because they do not perform the main function of the product. However, many of these 'inert' ingredients, such as petroleum-based solvents, may have significant ami toricolos Lat. Asan amples ut pt 5 aps nid harfmulful totoxxiiccoollooggiiccaall efffectfsaanenddmcmuuststtbsbee iinnccluldueddeiidnn y`yoour LLDDs,0 caallccuullaattiioonn.. A y , T1ohr awramsepdarfmodscwemoea sponLathe omer. 0 spol To calculate the estimated LD~o ofthe waste, use the f an aC wold eh tfbolllloowwiinngg ffoorrmmuullaa: Ch (Se SS) | nent infomation and novieage 1 Yw" L101e0 X ( CT~a.a + CTTaa~ + CTTe~c c ) Applying specific knowledge to determine the lethality of a waste As an alternative to calculating the estimated LD~ of a waste, you may apply specific mad docunrented knowledge of the materials and processes used in generating the waste. If the waste is an unaltered ddiissccaarrddeedd pprroodduucctt,, yyoouu mmuusstt ddeetteerrmmiinnee wwhheetthheerr tthhee product would reasonably lneet the Lethality characteristic when disposed of. Certifications or was is "non-ovic" informed statements waste is "non-toxic" orby or "practically notonic" to a product lnanufacturer that "practically non-toxic" to a humans or lnananrals may constitute knowledge that the waste is reasonably non-Lethal. If vou are able to locate some toxicological infbnnation but are tmable to calculate the estimated LDs0 of the waste, you may still be able to use the available data to evaluate the waste for the Lethality characteristic. As an example, if the only LD~o data you are able to locate is for an exposure method othcr than the one you arc considering, or if the test animal is different than the required animal for the exposure meflmd you are considering, you may apply accepted principles of biochemistry, toxicology, and physiology to the LDs0 reasonably be Lethal data you do have to determine reasonably be Lethal. whether the waste would Note: You may not rise information that a prodnct is cerlified for a specific use by a governmental agency, such as the U.$. Food and Drag Administration (FDA), U.S. Environmental Protection Agency (EPA) or other similar Federal or state pose of ules the ered us by snaadrackeof agency, as evidence that the product is non-Lethal when disposed of unless the certified use by its nature and lack of limitation shows that the produa ct would reasonably- be nonLm`meeetddhiiacclaa.llAuussseeanooffeaaxappmhhapanrlemm,aacyceoeuuutitmiccaaalyl bbnyyottthhueeseFFaDDpAAparsaosevavelivfdidoeernnlcicneefittthheaad~t the wastc pharmaccutical is non-Lcthal; howcvcr, thc approval for unlindted food use of an additive would reasonably iinnddiiccaattee tthhee aaddddiittiivvee wwaassttee iiss nnoonn--LLetehthala,l. When sufficient information and knowledge aarree nnoott aavvaaiillaabbllee ttoo ddeetteerrmmiinnee lleetthhaalliittyy T=LD ofthe wate uknnaobwlleetdogelotcoatdeetsuefrfmiicnieentwhineftohremaartiwoansatnddisplays Tus = LD.ofingredient A, B,. Z inthewaste Tw = LDso ofthe waste Ta,~,..~ = LDso of ingredient A, B, ...Z in the waste Coa 2% concumrion of ngrdicni A,B, .Zinthe | manage the waste a a Lethal hazardous waste or Cx,~, .z = % concentration of ingrcdicut A, B, ...Z in the ae noithe MPinCwritAing TheMPCA may wNoats:teThs total % concstions of ingrdicts A BZ you Note: The total % concentrations of ingredients A, B, ...Z you Veoclan oy be es hi WA 1 rent | detenmine whether the waste may be maraged 35 use in your calculation may be less tlmn lt10% ifthe relnainder it wa wll ot roc il xml lt non-Lethl of the waste will not produce a hamfful toxicological effect. WWhheenn,, aafftteerr eexxeerrcciissiinngg dduuee ddiilliiggeennccee,, yyoouu aarree. unable to locate sufficient information and tkthhneeoLwLeeltethhdaagllieittyytocchdhaeartraeacrctmeteririnisesttiiwcc,,heyytoohuuermmaaaywy aeesiitttheheedrrissspiimlmappyllsyy manage the waste as a Lethal hazardous waste or nrreeoqqtuiufiiyrreethsseppeeMcciiPffiiCccAaaddiddniittwiioornnitaailnl gee.vvaTallhuueaattMiiooPnnCttoAo rremeaaassyoonnaabbllyy determine whether the waste may be managed as non-Lethal. TThhee LLeetthnaallittyy Characters Characteristic WWaasstteer/Hiaazzaarrddoouuss WWaassttee #22..0055 + aMMaayy 22000099 page 3 33333322..00000033 & Mvisec nolution STATE 02770361 STATE_02770361 Specific published lathally information Specific published lethality information a any Table 2 lists specific lethality information currently Knowntothe MPCAfor wate which a may nost xh kno~vn to the MPCA for wastes which may not exhibit any of the other attributes from Table 1, with the oposite hy tsb concetionsfor the appro,'dlnatc lethality threshold concentrations for the ooTrrtaallleelxxpkpoonssuuorreewommneetpthhoootddenffootrrlecyaaccLhhetwwhaaaslsttwe.a.TsTthehisiss, taaabnblylee tddhoosceses not not `wldiwsehhtiincaclhihl etkthhdneeoaMwMnPndPCCoofrAAphbboeteileinetviclaelslhhymaasLayyes'ptheaocatirhlfewiircwasskitnseeeosw,nnloooetntdblgbyeee.those identified and of which it has specific kaaowledge. Table 2: Specific known lethaity information Table 2: Specific known lethality information Wastename Waste name Beryium Beryllium Fomadenyde Formaldehyde Gutaragenyde Glutaraldehyde [---- Perfluorobutanesulfonate (PFBS) Pertuoradecsacnao (PFO Perfluorodecanoic acid (PFDA) Pertuouodtanesutonste (PFO Perfluorooctanesulfonate (PFOS) Perfucroocanesu(lFoOSnAyoarPmFiOdSAe) Perfluorooctanesulfonylamide (FOSA or PFOSA) Pertucrooctanascidc PFO) Perfluorooctanoic acid (PFOA) CAS registry CAS registry Sumber _ number rasoer7 7440-41-7 50000 50-00-0 11208 111-30-8 0u20.403 29420-49-3 ns335-76-2 1ea231 1763-23-1 15451.6 754-91-6 snze2s.t 3825-26-1 tAAhpprpperrsoohxoiilmmdaatctoenlceletethnhatlarilaitttyyion threshold xconcentration 220%% Ey2O% oo27% 1m86% s11o%n a5uOs%, s34o%n 5O% Moorree iinnffoorrmmaattiioonn i metpolion counts PCA, in cooperation withmetopoitan cou The MPCA, in cooperation with metropolitan cotmty h`haazzaarrddoouuss wwaassttee ssttaaffff,, M Miinnnneessoottaa TTeecchhnniiccaall AAssssiissttaannccee Program (MATAP) staff and othe procs have Progranl (MnTAP) staff and other partners have ie ddeevveellooppeedd gguuiiddaannccee mmaatteerriiaallss aabboouutt tthhee hhaazzaarrddoouuss wwaassttee Teulon: vaiabs on MPCA's Web site Ewa tte mnus ast pubsbusinehasnsd regulations available on MPCA's Web site at w~w.ppecaa.state.mn.us/waste/pubs/business.html he MPCA ad your metropolican county szadous The MPCA and your metropolitan county hazardous atc offhaivescaelhst can hep ou. Contact your waste offices have staffthat can help you. Contact your metropolitan county or the MPCA ofc nearest sour metropolitan county or the MPCA office nearest your Tacitatho numbers below. MATAsia can provide facility at the numbers below. MnTAP staffcan provide emmahon Rahaputoleswsh. infom~ation and resources to help you reduce waste. Metro County Hazardous Waste Offices Metro County Hazardous Waste Offices Anoka County Tesei22109 Anoka County ........................... 763-422-7093 Carver Conny 9523611800 Carver Coun.ty .......................... 952-361-1800 DakotaCoury 9524917557 Dakota County .......................... 952-891-7557 Hemepin County i23453777 Hennepin County ...................... 612-348-3777 Ramsey County. 651.266.1199 Ramsey County......................... 651-266-1199 Scot County 952.496.3475 Scott County .............................. 952-496-8475 Washingion Couty 651-430-6655 Washington County ................... 651-430-6655 Websis woo couny mas Web sites ................... www.co, lcoun.tyl.mn.us Minnesota Pollution Control Agency Minnesota Pollution Control Agency ' TToollll ffrreeee a(allll ooffffiicceess)) ............. 11--880000--665377--33886641 BBiinnde. rd 2218n82a82i49n2 Brainerd ......................................218-828-2492 uh JT460 faDretroit Lakes ..............................218-L8y4r7e-1519 Dalat Ficerl Duluth ........................................ 218-723-4660 buts, Ja Mankato .................................... 507-389-5977 MaMrsahrsahlall.l ..................................... 550077--553377--77114466 Rochester Sraws7343 Rochester ....................................507-285-7343 Sta 1066300 St. Paul ...................................... 651-296-6300 Wilmer 50s Willmar ..................................... 320-214-3786 Web ie pasta ns Web site ......................... www.pca.state.mn.us Minnesota Technical Assistance Program Minnesota Technical Assistance Program i. sar01s Toll-free ................................. 1-800-247-0015 Minncapls. S12-624-1300 Minneapolis ................................612-624-1300 Wisi i pamela Web site ........................ www.mntap.umn.edu TneThe Leal Chance Lethality Characteristic Wostazdos Was 2.05 Waste/Hazardous Waste #2.05 - MMoayryt2600098 page 4 33333322..00000044 t ET y STAT 02770362 STATE_02770362