Atm,-m i INTEROFFICE MEMORANDUM Date: From: Dept: Tel No: 08-Apr-1998 02:34pm DAVID E.

PFOS: A DIETARY LC50 STUDY WITH THE MALLARD WILDLIFE INTERNATIONAL LTD.

AR226-1998 TRENDS IN C-8 IN AIR LEVELS FEE Area (Composite Avg.) .1980 C-8 T n Air' (mpb) AEL 0.56 1981 1982 1983 1.87 0.32 Not Calculated 0,15 FEE Wet Finishing Operator 0.95 0.30 FEE - No, 1 Clean Boom No. 2 Clean Boom 6;80 3.11 Fine Powder Dryer Operator 1.40 0.56 Fine Powder Dryer Boom (Composite Avg.) 3.00 2.47 0.09 3.54 0.15 0.37 0.11 0.19 0.06 0.23 JWR:ldr 10/19/83 AJP003476 EID077033

I AR226-2215 EID294840 il Vapor Scavenging Coeffioent Liquid Precipitation Frozen Precipitation C8 Particle Density 2.2 o/cm8 3 .0 -s .o 1.0 *3.0 0.5* 1.0 0.3 - 0.5 0.1 -0.3 f 1 |Lpif ill 13b ilia ifir li _ ' a te is based on testing conducted at the Washington Works site in September, 1996. 6 Particulate scavenging coefficients for liquid precipitation are from Figure 1*111nthe EPA ISC Users Guide (Volume II). 6According to Section 1.4 of the EPA ISC Users Guide (Volume II), the scavenging rate coefficients for frozen precipitation are expected to be reduced to about 1/3 of the values In Figure 1*11. 7.0% 12.5% 6.8% 31.5% 42.2% 5.5% 20,0% 0.25% 8.25% 66.0% 0.75% 1.75% 3.5% 25.0% 69.0% o;o% 16.5% 3.5% 42.0% 38.0%

FOR DU PONT USE ONLY AR226-2947 Ou Font (HR 127*90 ' r'.

AR226-2960 DU PONT USE ONLY Study Title STATIC, ACUTE, 48- AND 64-HOUR EC50 0 Du Pont HLR 457-91 [TO Daphnia magna Organisation for Economic Co-Operation and Development (OECD) Guideline for'fes ting Chemicals: 202 Author Kevin N.

AR226-3050 Study Title Skin Irritation Test with K-21946 in Rabbits Laboratory Project ID Haskell Laboratory Report No. 784-96 Authpr Tracy A.

(Ji i/tudy No. 16U45 TA.

p. 1 - byo'j Journal o f Toxicology: C linical Toxicology Jan 1996 v34 n l p 2 1 ( 4 ) Page 1_________________________________________________________________ Pulmonary toxicity following exposure to an aerosolized leather protector. by Keith K.

fifL - o 6 9 *> ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE_____________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95 or as a component of FC-201AF. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR - 02So ACU TE TOXICITY TO AQUATIC IN V ERTEBRA TES (DAPHNIA MAGNA) T E S T S U B S T A N C E ___________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to a s P F O S , FC-95, or as a component of FC -787 or FC 787X. (1-Octanesulfonic acid) (C A S # 2795-39-3).

AR 126-0043 : DETERMINATION OFTHE VAPOR | PRESSURE OF PFOS `USING THE SPINNING ROTOR GAUGEMETHOD `WILDLIFE INTERNATIONAL LTD.

CT 3M MEDICAL DEPARTMENT CORPORATE TOXICOLOGY AR216-0150 To: Andrew Seacat 220-2E-02 cc: John Butenhoff 220-2E-02 From: Marv Case 220-2E-02 Subject: Pathology Review Date: 22 July 1999 On 19 July 1999 during my visit at Covance, Madison, 1 did a slide review of selected tissue sections on the PFOS six-month monkey toxicity study (Study 6329-223).

SaAtZLeEeCEnN Roger G.

: 3M MEDICAL DEPARTMENT TOXICOLOGY SERVICES To: Georjean Adams 290-4-01 cc: John Butenhoff 220-2E-02 From: Marv Case 220-2E-02 Subject: FC 95 and 143 Teratology Date: 26 May 1998 John passed on to me your request for someone to review and write an analysis on the eye lens defect that was reported in the the toxicology study files on FC 95 original and FC FC 143. 95 rat teratology study.