/ ( ' .'

AR226-2397 Polymer Products Department cc: Research & Development Division Experimental Station CONFIDENTIAL M.

0750 ACUTE TO XIC ITY TO FISH TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (CAS # 2795-39-3).

CC: ERD Division Directors R.

R*082 REV. i*<J cstaiushio hoi E. [ . du Pont de;ncNorpeo*mato( ours & C o m pany Wilm ington.

.

ee fier eboney fpfibasrt tnd= AR226 -0HHO o TWO YEAR ORAL (DIET) TOXICITY / CARCINOGENICITY STUDY OF FLUOROCHEMICAL FC-143 IN RATS (RIKER EXPERIMENT No. 0281CRO012) Vouume 4 oF 4 ConpucTep DURING APRIL, 1981 - Mav, 1983 RIKER LABORATORIES, Inc. / 3M COMPANY ST.

AR286 -- 0733 `SUMMARY FOR WORK PERFORMED BY THE GERMAN ARMY ON FOAM EXTINGUISHING AGENTS MANUFACTURED BY MULTIPLE COMPANIES EST SUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95,oras a compoon fFeC-n 20t 3. (1-Octanesulfonic acid) (CAS # 2795-39-3).

AR 286 807 BIODEGRADATION (OECD 301E) TEST SUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f9l5u,oroorocatsanaescuolmfponoanteen,twhoficFhC-m2a0y6CalEs.o b(1eOctanesuifonic acid) (CAS # 2795-39-3).

Te WASHINGTON WORKS TEFLON DIVISION Sp-CF v - [oy = 0% 0 - ot a AL2267 1623 Cc: T.

389 20109 NEW C HE MIC AL M AT ERI ALS Vol 38 No9 75 710065 Progress in synthesis and applications of trifluoropropanoic acid Zeng JijunDu YongmeiZhang WeiKang Jianpin Hao ZhijunWang BoMa YangboLv Jian Xi'an Modern Chemist ry Research InstiuteXi'an 710065 AbstractPhysical and chemical properties of trifluoropropanoic acid w ere introducedDifferent preparation meth- ods and application progress in some fields such as synthesis of fluorinated compoundscatalysts and specific solvent w ere s um m ariz ed Key wordstrifluoropropanoic acidpropertypreparationapplication Oxone2K HS O5K2S O4K HS O4 5 1 1 CF3 1 RhC 2 CF3 3 4 2 CF3S O2ClCF3CdBr 333- -1- HCFC-1233zd 21 CF3SO2Cl AIBN CF3S O2Cl 333--1- 1984 ODS 76 38 25 HCFC-1233zd HCFC-1233zd 1 HCFC-1233zd 9 5 2HCFC-1233zd 10 6 3HCFC-1233zd Oxone 11 7 26 111333- CF3C H2CCl3 CF3C H2CCl2F CF3C H2CClF2 OleumS O3 H2S O4 12 8 3 31 CF3 311 2-13 2- 312 B1 B1 14 3 N- B1 B1 B1 313 U S5100751 15 32 16 17 33 18 19 4 20 HCFC- 115 9 115 15 6 T gT d 1 Cassidy P ET hermally stable polymers M New YorkDekker 1980 2 Yang H H Aromatic high-st rengt h fibers M New York Wiley 1989 3 Sheng-Huei HsiaoYu-Hui ChangNew soluble aromatic polyamides containing et her linkages and laterally attached p-terphenyls J European Polymer Journal2004401749-1757 4 M 1988 5 Lora JSoriaro BComposite membranes of aromatic polyamidemembrane peaparation and characterization J Deaolinut io n 198764375-386 6 Biw are M V Ghatge N DSt udies in piperazine containing poly sulphone-amides for use in w ater desalination J Desalinat io n 199510193-100 7 Iborra M LLora JEffect of oxidation agent s on reverse osmosis membrane performance to brackish w ater desalination J Desalination199610883-89 8 Wing-Hong ChanSuei YeeSynt hesis and characterization of random polyamide-sulfonamides3Copolymers f rom t w o diamino monomers J Polymer199533234503-4508 2010-06-12 2010-07-18 76 1233zd HCFC-1233zd 1 Henne A L Fox C J Ionization constant s of fluorinated acids J J Am Chem Soc1951732323-2325 2 Buyle O Lorent K Mat hieu V Process for t he manufact ure of fluorinated alcohols P EP1820789A12007-8-22 3 How ard M PLeonard O RRobert L SMarion E HImproved synt heses of et hyl 333-t rifluoropropionate and 333t rifluoropropionic acid J J Chem Eng Data197116 3 376-377 4 Ling XiaoT omoya Kitaz umeSynt hesis of some fluorinated acidsketones and alcohols derived f rom333-t rifluoropropionic acid J J Fluorine Chem19978699-104 5 Wakselman CT ordeux MSynt hesis of 333-t rifluoropropionic and 444-t rifluoro-2-ketobutyric acids J J Fluorine C hem 19922199-106 6 Bouillon J PMaliverney CMernyi RT rifluoromet hylation of aliphatic halogen compounds J J Chem Soc Perkin T rans199192147-2149 7 Munavalli E SLewis OMuller A JNovel reactions of perfluoro-2-t rifluoromet hyl-propene J J Fluorine Chem1993 63253-64 8 Yamanaka H T T akekaw a KMorita T IPreparation of novel -t rifluoromet hyl vinamidinium salt and it s synt hetic application to t rifluoromet hylated heterocycles J T et rahedron Lett 1996371829-1832 9 Komata T Akiba SHosoi KOgura KConvenient synt hesis of 333-t rifluoropropanoic acid by hydrolytic oxidation of 33 3-t rifluoropropanal dimet hyl acetal J J Fluorine Chem 200812935-39 10Komata T Akiba SHosoi KOgura KProcess for producing 333-t rifluoropropanoic acid P WO 2007052492A1200705-10 11 Van Der Puy MT henappan APreparation of fluoroalkyl compounds and t heir derivatives P U S 57771841998-06-07 12Veronique MOlivier BF rancine JPreparation of carboxylic acids P EP 1754697A12007-02-21 13Jimenze J MBemis GWang T ianshengKinase Inhibitors P WO 2008094992 A22008-08-07 14Wood M RAnt hony N JBock M GN-Biphenylmet hyl aminocycloalkanecarboxamide dernatives wit h a substit uent on t he met hyl usef ul as brad ykinin antagonist s P WO 2003066577 2003-08-14 15Kato EIshii KIshibashi HLiquid developing agent for elect rostatic photography P U S 51007511992-04-31 16 P C N 1012742262008-10-01 17 F P C N 17576392006-04-12 18 Yamamoto EIshihama Y Asakaw a N LC-MS analytical met hod and it s mobile phase P JP 20040772762004-03-11 19 Spaugh A T Vinyl ends measuring met hod P WO 20080974162008-04-16 20 J 200432944-46 2010-04-19 2010-06-03

internCaolrrespondence rc: P.

Experiment No.: Conducted At: Dates Conducted: Conducted By: Reviewed By: Acute ocular Irritation Test with T-3493 in Albino Rabbits 0884EB0008 Safety Evaluation Laboratory Piker Laboratories, Inc.

OCTANOLFWATER PARTITION COEFFICIENT TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may alsobe referredto as PFOA ammonium saltA,mmonium perfluorooctanoateF,C116, FC-1 26, FC-169, or FC-143.

ACUTE TOXICITY TO AQUATIC INVERTABRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may also be referredto as PFOA ammonium salt,Ammonium perfluorooctanoateP,FO, FC116,FC-126,FC-169,orFC-143.