Bynum Turner Ethyl Corporation 100 Park Avenue, New York 17, New York Dear Bynum; I have finally finished the memorandum or report on the evidence relating to the fourth miltiliter of tetraethyl lead, for the ublic Health Service and its Special Committee, and it will be on its way as soon as it can be multilithed.

This is the reason for my lack of opportunity to communicate with you prior to the meeting of the Committee. ) There are certain aspects of the use of tetraethyl lead, strategically, that are of considerable commercial and competitive importance, Not only would it be undesirable, from Ethyl's viewpoint (and I have no doubt that the same attitude applies to du Pont), to diecuns these matters fully with your Committee in the presence c du Pont representatives, but such a performance would probably be criticised justifiably by the Department of Justice if it were to be known, i strongly urge upon you, therefore, that this matter be dealt with openly by your group and the Committee, and that it be made clear to all concerned that the Committee is meeting with the representatives of the industry jointly, for purposes of mutual understanding, but also, fox the sake of being fully informed on matters that may be.of competitive significance, it will meet the two groups separately.

Kehoe, ' I have recently been asked certain questions about the canister masks used by men employed in the open-air transport of sludge containing tetraethyl lead.

Xehoe University of Cincinnati The Kettering Laboratory College of Medicine - Eden Avenue Cincinnati 19, Ohio Dear Bob: Thank you for your good comments on the first part of my memorandum on the value of the Uth milliter of Tetraethyl lead.

Your letter of April 15th addressed to Mr* Mtttnacht of the Ethyl Gasoline Corporation concerning the examination-of your employees who handle tetraethyl 1ad has been forwarded to me by Mr* Mittnaeht* You, are quite right in your under standing that your tm n re to be examined at intervale of approximately a year or In less time at the dis cretion of the physician who is responsible for the examinations* This Is to inform you that it is not on account of an oversight that you men have not yet been examined* We arrange the work of routine examinations in such a way as to suit, as far as possible, the convenience of the doctor who is in charge of the district in which your refinery is situated* Dr* Sanders has not completed his examinations in his territory, but Is expecting to do so very soon* and will undoubtedly com municate with your refinery shortly in advance of his visit* There was a time when w examined men who were mixing at intervals of three months* Somewhat later the interval was increased to six months by reason of our assuntrice fresa our experience that there was no justification for anxiety concerning the safety of the men# denewhat Inter the interval was Increased to a year but only on the basis of clinical and experimental evidence that the lead exposure associated with mixing operations is negligible so long as the equipment is correct and the precautions are properly carried out* We do not believe that there is any justification for lengthening the in terval of examination and we do not expect to do so* On the other hand we do not regard send slight variation in the length of time as significant so long as we have evidence in our files that the severity of exposure conditions has not been materially changed since the previous visit* Very truly yours, KE 0000488

Kahoe College of Medicine University of Cincinnati Cincinnati, Ohio Dear Doctor Kahoe: On March 12, 1929, you furnished us * very comprehensive and sympathetic statement of your study of the case of who since about June, 1924, has berxWHHSnfflj^^^^^Wl and psychic consequence of tetraethyl lead poisoning at that ti~o.

. , sollne containing Tetraethyl Lead is handled, and i N ^ h e r thayjiwrosene should be available to wash the hands in case any spilj.age^ecu^y' Again employees have been given instructions to wash carefully witlaTJdap and water before eating food or smoking.

Dear Henry: Your letter of August 23 concerning the agreement of the Surgeon General with the manufacturers of tetraethyl lead came during my vacation and, therefore, it did not receive the prompt response which it deserved in view of its timeliness.

I don't" think they have any idea that the tetraethyl lead content in.Q-treated gasoline had anything to do with this man's illness.

Beatty Ethyl Corporation 1600 West Eight Mile Road Ferndale 20, Detroit, Michigan Dear Hal: There is little that I can say by way of constructive criticism about your draft thus far of the memorandum or statement on the significance of tetraethyl lead in the development of high octane gasoline.

The blood cannot be used In this situation since the metabolic products of tetraethyl lead in the body do not combine with the constituents of the erythrba/te Thus the urinary load concentration reveals the level of absorption but the blood does not.

Moreover, as I have indicated, it is never seen in tetraethyl lead poisoning, and so your statement of its ''constancy1' la not correct.

It now appears that the combustion of tetraethyl lead in an air stream led through a gas burner will give us what we want in the form of lead oxide, without other undesirable constituents.

Moreover, as X have indicated, it is never seen in tetraethyl lead poisoning, and so your statement of its "constancy" is not correct.

1315 Substance 1,1,2.2-Tetrachloroethane--Skin Tetrachloroethylene see Perchtoroethy- lene Tetrachioromethane see Carbon tetra chloride Tetrachloronaphthalene - Skin Tetraethyl lead (as Pb)-Skin Tetrahydrofuran Tetramethyt lead (TMl) (as Pb)--Skin Tetramethyf succmonitrile--Skin Tetranitromethane Tetryl (2.4,6-tnnitrophenylmethylnitra- mine)-Skin Thallium (soluble compounds)-Skin Thiram Tin (inorganic empds. except oxide) Tm (organic empds) Titanium dioxide Toluene (toluol) : Toluene-2 4-dusocyanate o-Toluidme--Skin Toxaphene, see Chlonnated camphene Tributyl phosphate 1,1 1-Tnchloroethane, see Methyl chloro form 1,1 2-Trichloroethane--Skin Trichloroethylene Tnchloromethane, see Chloroform Tnchloronaphthalene -- Skin 1 2,3-Tnchloropropane 1.1,2-Tnchloro 1,2,2-tnfluoroethane Tnethylamine Trifluoromonobromomethane 2,4,6-Trinitrophenol. see Picnc acid 2,4 6-Tnnitrophenylmethylmtramine. see Tetryl Tnmtrototuene--Skin Tnorthocresyt phosphate Triphenyl phosphate Turpentine * Uranium (soluble compounds) (insoluble compounds) C Vanadium (VjO.dust) (V,0% fume) Vinyl benzene, see Styrene ppm8 5 mg/cu m' 35 200 05 1 200 002 5 2 0 075 590 0 075 3 8 15 01 5 2 01 15 750 0 14 22 5 10 100 50 1 000 25 1.000 45 535 5 300 7 600 100 6 100 - 15 - 01 -3 too 560 0 05 - 0 25 - 05 01 C Vinyl chloride Vinylcyanide, see Acrylonitrile Vinyl toluene Warlarin Xylene (xylol) Xyltdine--Skin Yttnum Zinc chlonde fume Zinc oxide fume Zirconium compounds (as Zr) Radioactivity For permissible concentrations ot radioisotopes in air, see U S Department ot Com merce, National Bureau of Standards Handbook 69.