ASBESTOS IS 1, First described in 1899 in London 2, 1930's - Asbestosis shown to be a major cause of DISABILITY IN WORKERS IN ASBESTOS TEXTILE INDUSTRY 3, Latent period of 10 - 20 years A, Symptoms & Signs A, Early a) Shortness of breath b) Chest pain ' B, Later c) Basal rales d) Clubbing of fingers e) X-ray changes f) Abnormal lung function DUP 1005305 DU 050942 PLEURAL THICKENING 1, Occurs early 2, May be only change 3, Not a feature of other kinds of pneumoconiosis 4, May become calcified a, Rarely occurs, i-Nless. than 20 years after first exposure b.

03 1600 13:07 FAX 301 951 1374 DISCLOSURE 002 l /V J ....

FILE NAME: Warning Labels (WL) DATE: 1939 July 18 DOC#: WL101 DOCUMENT DESCRIPTION: NPCA Labeling and Selling Dangerous Products A p p en d ix A ^ckiimtal ^?

FILE NAME: Electrical Insulation (ELEC) DATE: 1930 DOC#: ELEC001 DOCUMENT DESCRIPTION: Government Report-UK IRi.MK OFl-ICn \ "C *ux) (Sratvn C apyri-nt !

FILE NAME Industrial Hygiene Foundation IHF DATE 1937 Nov DOC IHF004 DOCUMENT DESCRIPTION Conference Proceedings of Special Meeting - AHFA AIR HYGIENE FOUNDATION OF AMERICA Inc.

% Air Hygiene Foundation of America, 4400 Fifth Avenue, Pittsburgh, Pa.

FILE NAME: BF Goodrich (BFG) DATE: 1938 DOC#: BFG057 DOCUMENT DESCRIPTION: Report from NSC Industrial Safety Series Compounding Materials Used in the Rubber Industry ^Compounding Materials Used in the Rubber Industry Pail 11--Dry Inoiganic Substain.es; Gums, Oils, Hesinous Materials and Waxes; Liquids and Gases Industrial Safety Series No.

FILE NAME: Phenolic Resins (PHR) DATE: 1936 DOC#: PHR031 DOCUMENT DESCRIPTION: Book Excerpt from Industrial Dust; from Eagle Pitcher File CiA \ ff."

FILE NAME: General Refractories Company (GRC) DATE: 1934 May DOC#: GRC022 DOCUMENT DESCRIPTION: Trade Journal Reference Documenting Knowledge of Preventive Measures Knowledge of Preventive Measures Date: May 1934 Source: Mr.

FILE NAME: National Safety Council (NSC) DATE: 1934 June 18 DOC#: NSC313 DOCUMENT DESCRIPTION: Letter from Asbestos Paper & Allied Products Division of the Asbestos Industry to Keasby & Mattison Co.

FILE NAME: National Safety Council (NSC) DATE: 1935 DOC#: NSC215 DOCUMENT DESCRIPTION: NSC News Article - No Half Way Measures in Dust Control ; : ^ By A R T H U R S.

FILE NAME: New York State & NY Times (NY) DATE: 1936 DOC#: NY074 DOCUMENT DESCRIPTION: NY Law - Article 4-A Silicosis and Other Dust Diseases 1990 L aws o r New Yoke, 19dG I C u a i*, 'r .

FILE NAME: Cal Portland Cement (CPC) DATE: 1935-1937 DOC#: CPC002 DOCUMENT DESCRIPTION: Transcript o f Hearing before CA Insurance Commissioner STEPHEN L.

FILE NAME: Caterpillar (CAT) DATE: 1937 July DOC#: CAT034 DOCUMENT DESCRIPTION: Trade Journal Article - Pit & Quarry --J Voi. 30 Published on the tenth of each month for producers and manu facturers of Cement, Crushed Stone, , Gypsum, Lime, S e n d , Gravel and other nonmetallic min erals.

FILE NAME: Engineering (ENG) DATE: 1936 May DOC#: ENG025 DOCUMENT DESCRIPTION: Published Conference Presentation - Pneumoconiosis PNEUMOCONIOSIS ROBERT B.