Tetraethyl Lead Poisoning. 1925 N17476

Garl Mueller of the Chemnyco, Inc. regarding the 1 G, patent on the use of fluorides ^ for stabilizing tetraethyl lead.

,,was, injured; . through the use' of gasoline containing tetraethyl lead.

Kehoe has spent many years of research and clinical investigation both on the subject of tetraethyl lead and ethyl gasoiinej and there is no one in the country more competent to give you information which you seek than he, - I trust that you will hear from him within a very short time, With my very kindest regards, I am - . .. .

This morning I contacted the men who are working directly with tetraethyl lead with the purpose of correct ing as far as possible the gross errors in handling so that you can devote your short time here to the less evident' hazards.; In checking through our work on the chlorphenols I find that we have run some toxicities .studies on intra venous injections.

Drinker; I am sending yon herewith a rather lengthy article on the study of the Industrial and public health hazards related to gasoline containing tetraethyl lead.

You will note Mr, Crane states it is entirely possible to draw off sludge with the gasoline during tank car or barge loading opera tions, and it is my thought that possibly some Tetraethyl Lead was carried to the Cleveland tank in this manner.

December 8, 1933 Mr, Philip Drinker Harvard School of Public Health 55 "^an ^yka street Boston- Mass, *' 'f Dear Mr, Drinker; I am sending yon herewith a rather lengthy article on the study of the Industrial and public health hazards related to gasoline containing tetraethyl lead.

Sinoe th abore haarlnga, a uumber of confrences hare been held between reprsentatives of th ohemieal aianufacturar, th repaehere, ihtereeted solentista, and offieer of th Publio Mealih Serriee, for th purpose of dereloping agreemente thioh it i beliered vili eatiafaoterily prtant th publie Thi e followed a procedure imilar to that e&ployed In other agreemente, euoh aa that between th Publio Health Serriee and manufacturera of tetraethyl lead, and th agreement vlth th manufacturera of methanel Ceaplying vlth your quest, I am enoloelng a oopy of th agreement, together vlth copies of th labels agreed upon* i i Vi RRS:LA 1& T " --, tory truly yours, H.S#Ouamlng Surgeon General

The composition of the present ETHYL Fluid containing ,75 theories of bromine is as follows on a weight percentage basis:- Tetraethyl Lead * Ethylene Dibromide Ethylene Dichloride Kerosene and impurities Dye 61,69 26.88 7.55 3.76 .12 The specific gravity at 20 C. is 1.6475.

I am of the opinion that your warning sign as submitted for use on tanks WARNING Contains Tetraethyl Lead Contents poisonous.

Kehoe: I received your very excellent reprints concerning tetraethyl Ethyl lead and gasoline dermatitis and viish to thank you very kindly for the same.

In talking to Dr.Fischbein the other evening he was very positive that this man had a minor case of tetraethyl lead poisoning.

I have hoped that tetraethyl lead might find some usefulness here, but I am extremely skeptical.

In our somewhat scanty experience this has not given favorable clinical results, nor have we been able to demonstrate any unusual localization of lead in the tumor# I have hoped that tetraethyl load might find some usefulness here, but I am extremely skeptical.