AR226-3149 DuPont-3871 TRADE SECRET Study Title H-23960; In Vitro Mammalian Chromosome Aberration Test in Chinese Hamster Ovary (CHO) Cells Authors Ramadevi Gudi, Ph.D.

AR226-3206 TRADE SECRET Study Title H-24042: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Supplement No. 1 Laboratory Project ID: DuPont-2931 AUTHOR: Carol Pinlay, B.A.

, p ~2 ~a6_ 33 9~6 gE,y~ _ r 204 - ~ sg g ~ 2550 PATTON B000S N LIP AIIORNEYS Al lAW M Street, N W ~z oz S1760o0DC20037-1350 DEC 0 O {('~ P~ ~' : 3 Facsimile202-457-6315 U www.pattonboggs .com December 10, 2004 I'cter D.

aerf March 21, 2003 ARas6 -- 1220 To: Mary F.

Larry IL Zobel,MD, MTH StaffVice President and Medical Director 3M MedicalDepartinent 3M Center,Building220-2E-02 PO Box 33220 St.Paul,MN 55133-3220 651733 5181 Office 651733 5152 Facsiiy@le April25,2000 Dr.

Summary N-ETFOSERatTeratology SLu&Numbers:3M T-6316.7A,rgus418-011 Comi)ound&Lot: N-ETFOSE (N-Ethyl-PerfluoroocyanesulfonamidoEdm-oLlo)t FM3923 (30035, 30037,30039) 98.2% pure(SMD AnalyticaRlequest52489) AnalyticaDlocumentationfiledalongwith finalreport.Note - same lotas used intwo-yearratcarcinogenicitsytudy(T-6316,Covance 6329-212).

TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may alsobe referredto as PFOA ammonium salt,Ammonium perfluorooctanoateP,FO, FC116, FC-126, FC-1 69, FC-143 or as the major component ofFC1015.

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonatweh,ich may also be referredto as PFOS, FC-95, or as a component of FC-203CF-X or FC-203CF.

BIODEGRADATION (301E) TES -SUBSTA JCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, or as a component of FC-206. (1Octanesulfoniaccid)(CAS # 2795-39-3).

TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonawtheich may alsobe referredtoas PFOS, FC-95, oras a component of FC-3003. (1Octanesulfoniaccid)(CAS # 2795-39-3).

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, or as a component of FC-3017. (1Octanesulfoniaccid)(CAS # 2795-39-3).

ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity:A mixturecontainingperfluorooetanesulfbnatweh,ich may alsobe referredtoas PFOS, FC-95, oras a component of FX-3103. (1Octanesulfoniaccid)(CAS # 2795-39-3).

AR226-3634 B } geen em 5 =eF- E 3g oP: smocpeene : e2 i 31 i [a 5 - i 2 $% ir 3 10 v7 7 Z V F~~ i} 2 -- Wy a et we S22 Jk W =} on x0 So ororsz WP EELE J se . 3$ S+E STbperatenay sseaats dRiewi52 e $ SSaesaatwar ?

ER sup ARA26- 3652 [SteName | Location SampleDatJe [Bele |Charleston WV] 2004} [ChambersWorks|DeepwaterNJ| 2005] [D[ordDreco ht rd| |r"NNe eetthhc eerrlaahnnddst s| |__2_0_0_0,_2_00220:200505| EE [Fayetievile [VilersSt Paul nl ud ||"FayeFtriaevniclee,NC||" 2002,22000043,,22000055}| 0 & PFDOuAPoInntBlCooomdpSaenryum (perform occasSielolnealPloavner(iCmheacrovteerasgWoeAn)a,WMaescnhairnigcosn(WSoarmkpslesdiin-2P0a0r4k)ersburg, WV) [MechanTi8.c14 | ----a -- -- TrTT-- -- -- -- rrTT-- -- -- -- -- rr-- -- -- -- Tir---- -- --TTror ---- -- i-- | | Wechanic 1239] -- --=rT-- -- [Mechanic [134] [[eMecc -- hhaannirecr-- TT17704131] -- -- rerr---- -- [feeTc -- h1a 1s| -- -- =eT---- -- To-- [Mechani 732c ] -- = -- -- [-- V--iechraTn--ie--0T" Toot [Mec -- h-- an -- [i 54c 8| [AvengeeTl] -- MSte andad rd Di -- eviaa tionn ]E75E| 10] quaniiable A(n0aal=ys1ispboybBxygen Research, State Colge, PA QC dupicates un average valuesshown 72 LO uasd or statics BarvaraJ.

3M (;erteral offices 3Vt Center St Paul, N1AT 55144-1000 651'331i10 June 6, 200 5 A~A zz p. 1 7~ ?