3M Environmental Laboratory FinalReport-AnalyticaSltudy Single-dosIentravenouPsharmacokineticStudy ofT-6246inRabbits In-VivoStudy ReferenceNumber: HWI#6329-159 Study Number: AMDT-042095.1 TestSubstance: FC-95 (T-6246) Name and AddressofSponsor: 3M SCD Division 367 Grove Street St.Paul,NIN 55106 Name and Address ofTestingFacility: 3M EnvironmentalTechnology & Services 935 Bush Avenue St.Paul,MN 55106 Method Numbers AMDT-M-1-0, AMDT-M-2-0, AMDT-M4-0, AMDT-M-8-0, AMDT-M-14-0, and Revisions: Thermal Extractioonf Fluorideby means of a Modified Dohrmann DX2000 OrganicHalideAnalyzer-Liver FluorideMeasurement by Means ofan OrionEA940 ExpandableIon Analyzer ExtractionofFluorochemicalsfrom RabbitLiver AnalysisofFluorideUsing theSkalarSegmented Flow Analyzer with Ion SelectivEelectrode Thermal Extractionof Fluorideby Means of a Modified Dohrmann DX2000 OrganicHalideAnalyzer-Serum InitiatioDnate: See attachedprotocol Author:James D.

Acute PFOS ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

WATER SOLUBILITY (BY ANALYSIS OF TOC) TEST SUBSTANCE IdentityP:erfluorooctanesulfflounoyrlidmea;y alsobe referrteodas POSF, or FX-8. (1-Octanesulfonyflluoride, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafClAuSor#o-3,0735-7).

Special lans Or&l Toratology Study of T-2999CoC in Rats Experiment No,: Conducted At: Dosing Period: Stu4y Director: 0680TROO20 Safety Evaluation Laboratory Riker Laboratories,, Inc.

Experiment ]No.: Conducted At: Dates Conducted: Conducted By: Reviewed By: Acute Oral Toxicity Screen with T-3493 in Albino Rats 0884AR0010 FFLC131l@00 1984 Safety Evaluation Laboratory Riker Laboratories, Inc.

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MICROBICS MICROTOX@) TOXICITY TEST TEST SUBSTANCE Identity:Perfluorodecanesulfonatea,mmonium salt;may also be referred toas PFDS, FC-1 20, or 3M Sample J2905-1.(1-Decanesulfonic acid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,1100-,10, heneicosafluoro-a,mmonium salt,CAS # 67906-42-7) Remarks: Test sample isa mixtureofthe testsubstance inwater and butylcellosolve(approximately25% testsubstance,37.5% butyl cellosolveand 37.5% water).Allvaluesreportedrelatetothismixture.

Bio/dynamics Inc.

oral Toratology Study of T-314ICoC in Rabbits RECE!

ACUTE TOXICITY TO AQUATIC INVERTABRATES TEST SUBSTANCE (DAPHNIA MAGNA) Identity:Perfluorooctanoiaccid,ammonium salt;may alsobe referredto as PFOA ammonium salt,Ammonium perfluorooctanoatPeF,O, FC116,FC-126, FC-169, FC-143 or as the major component of FC1015.

BIODEGRADATION (BOD/COD) TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonwahtiech may alsobe referredto as PFOS, FC-95, or as a component of FC-201 F. (1-Octanesulfoniaccid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassiumsaltC,AS # 2795-39-3) Remarks: The 3M productionlotnumber was notnoted.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may also be referredto as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonicacid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassium saltC,AS # 2795-39-3) Remarks: The 3M productionlotnumber was notnoted.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, oras a component ofFC-603EF. (1Octanesulfoniaccid)(CAS # 2795-39-3).

MICROBICS MICROTOX@ TOXICITY TEST TEST SUBSTANCE Identity:Mixturecontainingperfluorooctanesulfonawtheich may alsobe referredto as PFOS, FC-95, or as a component ofFC-3003. (1Octanesulfoniaccid)(CAS # 2795-39-3).

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