AR226-2818 The Embryo-Fetal Toxicity and Teratogenic Potential of Ammonium Perfluorooctanoate (APFO) in the Rat (Work Done for Hire) Robert E.

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- 9 Ape 22,3003 Ch0riMs 1mShaaman Ar22-1692 StfH EoPssHenBduigdainnegrs r0 mpaonm DmE Seioen, Dese Ms Whitman, As today ionmota EaaieDyy,o wseiehmssassopaeclieadlmaapptriooprninmeefogrmeh0e sreius e{ommorniumea Peerfluorioeohcstsapnsoaotmety(Cse8en)cropanrndombeelneetmtapl1erbpoestursa(ttehdeorntthee uensuespedcti$n1g5p0ub1l)ic by 1 worked foratshoe DuncPoonvtoeCmoemnpgaemnryvoufocsrhotmsaennoy yesnarestaonaodayhoaruvesandoiirmeyocmtoklunsaolnwylSebdiegceaeouesfeot|hseeirhre for my safety as a result ofwhl this company might doo meifmy identity were known `While I worked olan 0 management snd wh regrly etend by thir for them, like some other Dupont workers, I regularly tried to do the right corporante "isseecuroibtayco"kfigtwoohoenonpsutufbhoeirydcdopoeniugangbtaslno.ys[ohdunniydhonmfoyptwohiwinhneaognruwttrdotsonopigDe.nunpdTooihnnnetlayrnheydelemmyoynaencyda.4nedfaTrhtkhedaeitfatehreeynt O altruistihcn eDnfuplooonotkohissapvaswrhotraoretfpetshtahcoyeendpCpacsotor.rpiiRorannabtie1Bdg0tidnc.oym1pyetaevnnOrdcyeh,iownnHredoesintfygf.eorTenhdcieyassnDdauponovnertatndNo Ee Their actions are et de. corr and the direct result of informed aonhdedrealiibsercarteeudemcuisnitonhsebyegDaulPpornotces 5 `pertains to the use of and the environmental release and/or disposal of C8.

Qualityassu Exposure A QualiAtsysuranPcreojePcltan Abld-CiSttyudSyamplinTgaskM 00666) ReWsioNno.: EffectDiavteeM:ay 14,1999 Pageiofiv QualitAyssurancPerojecPtlan for EmpiricalHuman Exposure Assessment Multi-CityStudy SamplingTask To (Confidendal) May 14,1999 Prepared by Battelle 397 Washington Street Duxbury,NU 02332 (781)934-0571 APPROVALS -D6n-dd Gunder Date SamplingTask Leader Ros.qnn Buhl Date BattellSeampHng Task QA Officer Mfir6iaNishiorca Date BattellPerojectManager Date BattellPerogramQA Office/ Date QualitAyssurancPerojecPtlan Muln-CitSytudySamplinTgask(NIO0666) Joseph Fficsel Marcia Mishioka Suan Abbgy Donald Gunster Rosanna Buhl Wayne TndU ScottMacomber ChrisGapon Kellyhizarry Robert Mandeville RichardRestucci Kim Andrews DistributLiiosnt RevisioNno.

3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY ProtocolforStudyNo.

ARR26_ 34 20 Pp PS i Pe 000220 2 o.

*iha AR22E _ 3626 Eo TECHNICAL REPORT SUMMARY 70: TECHNICAL COMMUNICATIONS CENTER -- 201-2CN important =Hfmportpeintedcnbotsidesofape,mdtwcopes 9TCC.)

3) OECD 404-OPPTS 870.2500, Acute dermal irritation (rabbit), 132-004 -IC e' .I < Acute Dermal Irritation Study in New Zealand White Rabbits Study Number: 132-004 ACUTE DERMAL IRRITATION STUDY OF T-7485 APPLIED TO NEW ZEALAND WHITE RABBITS STUDY NUMBER: 132-004 SANITIZED SPONSOR 3M Corporate Toxicology 3M Center, Building 220-2E-02 P.O.

PHOTODEGRADATION EFT7-2 TEST SUBSTANCE Identity: Perfluorooctanesulfonate; FC-95. (1-Octanesulfonic may acid, also be referred to as PFOS or 1,1,2,2,3,3,4,4,5,5,6,6.7.7.8,8.8- heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: Testing is in progress. 00211 PHOTODEGRADATION TEST SUBSTANCE Identity: PFeCr-f9l5u.or(o1oc-tOacnteasnuelsfuolnfaotnei;c macaiyd,a1l,s1o,2b,e2.r3e,f3e,r4r,e4d,5t,o5a.s6,P6.F7.O7S.8o.r88heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks field: The test substance is a white powder.

Maze- 46S 3 ..

AR226-0500 ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; mayalso be referred to as P11F6O, AFCa-m1m26o,niFuC-m16sa9l,t,oArmFmC-o1n4i3.um(pOecrtfalnuooircooacctiad,nopaetnet,aPdeFcOa,fiFuCo-ro, ammonium salt, CAS # 3825-26-1) R14e3m.arIkt'ss :puritTyhweas3Mnoptrsoudfufcitciieonntllyotchnaurmabcteerriwzaesd,8t3h.oTuhgeh test sample is FCcurrent information ainnddicCastepseritflisuoaromiaxntaulroegoufe9c6o.5mp-o1u0nd0s%.test substance and 0 -- 3.5% Cs, Cr, METHOD: Method: Not noted.

\ AR 226 -- 0589 | TSCA .

Wildlife International, Ltd. ae Project Number 454-107 PFOS: `A FLOW -THROUGH LIFE-CYCLE TOXICITY TEST WITH "THE SALTWATER MYSID (Mysidopsis bahia) ADDENDUM `WILDLIFE INTERNATIONAL, LTD.

vim AR226-2370 Example calculation of chemical toadfngand groundwater response.

AR226-2453 ^aboacatory Hame: CH2M_HIjjI._ X,ab Sannple ID: M6X44002 Client Sample to: WBM^-336 O&Q&HICS .