-;-:%- AR226-2795 Haskell Laboratory Report No. 586-85 Naslcell LabEo.raIt.ordyu foPorftTt odxeicoNlsosgoyursandfimI!

AR226-2863 Material Tested Copies to; E.

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| AR 246 - 3229 | a1 | ARARG _ 3427 DuPont-8867 TRADE SECRET Study Title 'H-25170: Bacterial Reverse Mutation Test with an Independent Repeat Assay Authors Valentine O.

Development of a Mammalian Screen to Evaluate Absorption and Persistence of Fluorina C Finlay, G.

Fluoroc Sample CentreAnal icalLaboratoriesI,nc. 3048ResearcDhrive Phone: (814)231-8032 StateCollege,PA 16801 Fax: (814)231-1253or (814)231-1580 An -aI-W-(AL;Mal Report Fluorochemical Characterization of Drinking Water Samples Pensacola,Fl (W2176) Centre AnalyticalLaboratoryReport No. 023-007D TestingLaboratory CentreAnalyticLaalboratoryI,nc. 3048 Research Drive StateCollege,PA 16801 3M Environmental Laboratory Contact Kent R.

CENTRE FOR XENOBIOTIC RESEARCH UniversityofDundee, BiomedicalResearch Centre,Level5,NinewellsHospitaland Medical School,Dundee, DD1 9SY Study Report Determinationof cyanideinsensitivPeaimitoyi-CoA oxidationinsamples from 3M Environmental Laboratory - Covance Studies6329-183 and 6329-212 Study Number XR0108 Author: Approved: t.M.Elcom,be C.R.EL .e- XR0108 PaLyeI of 3 Date: I Introduction The purposeofthisstudywas toinvestigattehelevelsof PCOA oxidationinthefrozen liversamplesprovidedby 3M EnvironmentalLaboratoryfrom Covance studie6s329-183 and 6329-212. 2 TestSubstance 6329-183:PFOS, 20ppm, administeredby Covance untilweek 4. 6329-212:ETFOSE-OK 100 and 300ppm, administerebdy Covance untilweek 4. 3 TestingFacility CentreforXenobioticResearch,UniversityofDundee, BiomedicalResearchCentre, Level5,NinewelisHospitaland MedicalSchool,Dundee,DDI 9SY, UK. 4 Homogenste Preparation 4.1 Reagents SET buffer0:.25M Sucrose,5mM EDTA and 20mM Tris-HCI,pH 7.4 4.2 Instruments Potter-Elvehjehmomogeniser 4.3 Method Frozen liversampleswere thawed on ice,blottedand weighed.A 25% homogenate was preparedinicecoldSET usinga Potter-Elvehjehmomogeniser(6passes). 5 Determinationof Cyanide-in.sensitPiavlemitoyi-CoOxidation The 25% homogenate liversampleswere dilutedI partin 10 partswithicecoldSET.

-@ l@@ 1@4 -I----m cov ArgoooCoomE@m THE DEVELOPMENT SERVICES COMPANY DraftReport 13-Week DietaryToxicityStudy withN-Methyl PerfluorooctanesulfonamiEdtohanol(N-MeFOSE, T-6314) inRats PREPARED FOR: 3M St.Paul,Minnesota COVANCE STUDY NUMBER: 6329-225 COVAW-C'E'."'

3M Environmental Laboratory ( Final Report- Analytical Study Single-dose DermalAbsorption/Toxicity Study of T-6049 in Rabbits In-Vivo Study Reference Number: HWI#6329-130 Study Number: AMDT-020895.1 Test Substance: FC-95 (T-6049) Name and Address of Sponsor: 3M SCD Division 367 Grove Street St.

M2E5E0-12= MICROBICS MICROTOX TOXICITY TEST TEST SUBSTANCE Identity: PFeCr-f9l5uoorrooacstapnaerstuolfftohneatme;ixmeadypraoldsoucbteFrMe-f3er6r2e0d t(oseaes RPeFmaOrSkso)r.

Group Summary P Generation AR 23611226 Gop colichou Gus eames oes WotR motes moti an Gene es mJpoTtn[[c oorreon TTeemm [o7 ToTTaesee[[e 5oTon ee]][[aso a1[[asse]] FFCr os eonf no f 0 c0J Joust or 000050 P Generation Animal 1D Group Me"mCcernaas eB02111 337250 11080048 11 337657 1153000056 11 35735 10308078 11 440205 e8018 011 442255 wBeetz 11 45050 wBeettss 11 450000 8Be1es 11 54030 1B0e81s7 11 440000 8e81290 11 440000 ese2e 111 440205 R10e62s4 11 344000 see2s 611 i357157 [62E8a 1 432755 6B2011 40000 8wes2t 22 432657 11988343 22 430705 11888S% 22 440000 1988722 4045 10B 22 34735 Bmea2r 22 347050 1B4443 22 4a2755 16 845 22 440000 1w9e4e7 22 440000 meevenioesr 560000 450000 530000 540000 500 540000 250000 440000 550000 550000 450000 550000 560000 550000 440000 550000 550000 550000 250000 250000 540000 450000 440000 540000 500 000051 P Generation 13849 2 400 500 13850 2 425 600 13851 2 325 600 13852 2 375 500 13853 2 400 400 13854 2 400 500 13855 2 375 500 13856 2 ars 400 13857 2 450 400 13858 2 400 500 13859 2 380 500 13860 2 425 500 13861 3 500 300 13862 3 375 500 13863 3 400 500 13864 3 467 400 13865 3 400 400 13866 3 467 300 13867 3 400 500 13868 3 ars 500 13869 3 400 500 13870 3 400 400 13871 3 375 500 13872 3 37s 500 13873 3 400 500 13874 3 500 300 13875 3 400 400 13876 3 375 400 13877 3 425 400 18878 3 425 500 13679 3 400 600 13880 3 400 400 13881 3 500 400 13882 3 400 500 13883 3 ars 500 13884 3 400 500 13885 3 4DIVOl FALSE 13886 3 vel 100 13887 3 400 500 13888 3 400 400 13889 3 375 400 13890 3 400 500 13891 a 400 500 13892 4 425 500 13893 a 375 500 13894 4 375 500 19895 4 400 500 1386 4 450 400 1387 4 400 500 13898 4 ars 400 13899 4 400 500 000052 110010 44 1130028 44 1109990045 44 11809076 44 11890098 44 1WO0U 44 1m8o1t82 44 19145 44 O1176 44 w11e9 44 1B2210 45 B12223 55 110802254 55 182267 55 11882298 55 1Bes0t 55 B 1%255 14 55 1188%7 55 BBWW 55 1184401 55 1B843255 119894454 55 6 B47 55 11394489 55 160 5 P Generation 460000 350000 440000 550000 450303 240000 452353 350000 442050 450000 450303 440000 44725 450000 45235 400 500 450303 500 300 440000 550000 347050 550000 440000 450000 430600 550000 337755 500 500 D3i7v5o 41.0000 432755 500 500 430705 550000 452353 500 300 347050 550000 44030 450000 54030 450000 442050 440000 440205 550000 347657 550000 356070 450000 425 500 000053 | P1 estrous cycle data Grou|p re EEE mE --E = ER d E HeNppT Rg Teye -- = He I RL --=ES BERELaSE yTeay pmy ing --= og fa (Tal TEE CBE ---- BE paC ti:paialyF TE RLLSREEIY- EEgR: ---- --== S i HCyIyH BRyEHyREN HoEH IT oEH LEBae --%EHEC T for nl e el wl]: 000054 | P1 estrous cycle data Group II JEE CTETE er ---- =---- E B yH REL Re H ee E ay 80 an "oan Bg THHg [lei E = e Beg e oee r a --= off gp HEEL HE CR = LI TE He 00055 P1 estrous cycle data Group lll ARE aa Ra a a "i plkaraidtart --ss=B oeL Bngdl`He L g Bh Ra L Ha BHH g: -- = PE re gy co RH gy a === FE ltda peal: pt i =.

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AR226-048Y SOIL ADSORPTION TEsTsuesTANcE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, PFO, FC-116, FC-126, FC-169, or FC-143.

AR 236 - 0830 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) IEstsusstANCE 000000000 Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1122,334,4556,6,7,7,88,8- heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was not noted.