5) OECD 406-OPPTS 870.2600, Skin sensitization (guinea pig), 132-015 Study Number: 132-015 Page 1 DELAYED CONTACT HYPERSENSITIVITY STUDY OF T-7485 IN HARTLEY GUINEA PIGS (MAXIMIZATION TESTI) STUDY NUMBER: 132-015 SPONSOR 3M Corporate Toxicology 3M Center, Building 220-2E-02 P.O.

3M ENVIRONMENTAL LABORATORY METHOD ANALYSIS OF POTASSIUM PERFLUOROOCTANESULFONATE OR OTHER FLUOROCHEMICALS IN LIVER EXTRACTS USING HPLC-ELECTROSPRAY/MASS SPECTROMETRY Method Number: ETS-8-7.0 Adoption Date: 0F[2219% Author: Lisa Clemen, Glenn Langenburg Approved By: 7 2 1p Laboratory ager ftom tr Group Leader nh Clysnee Technical Reviewer Revision Date: NA 2h for Date 2/4139 Date o7lilpy Date 1.0 SCOPE AND APPLICATION 1.1 S'HcPoLpCe-:elTehcitsromseptrhaoyd/miasssfosrptehcetraonmaeltyrsyi.s of liver extracts for fluorochemical surfactants using 1.2 Applicable Compounds: Fluorochemical other ionizable compounds.

gr 25, 1399812:41PK POREDICAL 220 ZF 02c@oucuTess + E7zi77s %0. 0773 5253 ' REPORT EVALUATION OF THE MUTAGENIC ACTIVITY OF 1.6506 IN AN JVNITRO MAMMALIAN CELL GENE MUTATION TEST WITH L5178Y MOUSE LYMPHOMA CELLS (WITH INDEPENDENT REPEAT) NNOOTTOOXX SPurbosjteacntce22738475481 * page 1 of 31 - , ~ ._ 738 MZ emiroars ag i asa samen2een i : ry i --_--r-i80b i 001362 UN 25, 1398912: 41PM POHEDouICAL 220 JFE Q2ENMOUTERSTERS+ 67331773 Ho.0mE3 E3 T-6906 S-T_ATEMENT OF GLP CoupLIANCE NOTOX Project 223458 !

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BACK TO MAIN -I-l-l-I-l-CI--I-l-1-A.A - J ~ ~ - - I U - C - C I - ~ - .

BACK TO MAIN 3M Medical Department Study: T-6295.10 Analytical Report: FACT TOX-099 LRN-U2400 Study Title Oral (Stomach Tube) Developmental Toxicity Study of PFOS in Rabbits Analytical Laboratory Report Title Determination of the Concentration of Potassium Perfluorooctanesulfonate (PFOS) Fluorochemical in Rabbit Liver and Serum Specimens Data Requirement Not Applicable Author 3M Environmental Laboratory Analytical Phase Completion Date at signing Performing Laboratories Liver and Serum Extractions Liver and Serum Analyses Pace Analytical Services, Inc.

BACK TO MAIN SRPT REPORT DETERMINATION OF THE PARTITION COEFFICIENT (N-OCTANOL/WATER) OF T-5874 BY HIGH PERFORMANCE L I Q U I D CHROMATOGRAPHY (HPLC) -.-.

3M Medical Department Study: T-6295.4 Analytical Report: FACT TOX-002 LRN-U2121 Study Title 104-Week Dietary Chronic Toxicity Study with Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) in Rats (Covance Study No.: 6329-183) Analytical Laboratory Report Title Determination of the Presence and Concentration of Perfluorooctanesulfonate (PFOS) in Liver and Serum Specimens of Crl:CD(SD) IGS BR Rats Exposed to Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date At signing Performing Laboratories Liver and Serum Analyses 3M Environmental Laboratory Building 2-3E-09, 935 Bush Avenue St.

AR226-2356 "Steve Williams" <steve.willlams@epa.state.oh.us> on 01/27/200410:17:55 AM To: cc: Subject: Andrew S Hartten/AE/DuPont DuPont "Michael Preston' <michael.preston@epa.state.oh.us> Re: Draft Surface Soil Procedure Andrew, I looked over the draft soil/biota sampling procedure and have a few questions/comments.

E.tiGlNEERiMS ROMP'-nAT^ y^-' AR226-2373 -- '',';'"--------------^- -----:7-- T-^-----

AR226-2424 LETART LANDFILL 6ROUNDHATER HONITORINg - SUMMARY Of PC-143* ANALYTICAL RESULTS Sample location Upper Pond Lower Pond Upper Pond Lower Pond Well 1 Well 2A Well 3 Well 3A Wen 4 WeU 5A WeU 5B WeU 8 Upper Pond Lower Pond Upper Pond Lower Pond Well SB Well 5A Well 4 Well 5A Duplicate Upper Pond Lower Pond Well 3 WeU 3A Well 7 Well 1 Well 8 Well 8 Duplicate Well 6 Well 2A Trip Blank Date^Sampled 1/18/91 1/18/91 2/8/91 2/8/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 3/22/91 4/26/91 4/26/91 *11/22/91** 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 11/22/91 FC-143 Result (ug/1) 2,900 1.200 2300 400 60 50 390 380 690 1.6 340 25 500. 340 930 670 380 0.8 830 0.9 790 1,000 1,000 350 O.I 68 280 280 24 63 0,1 * FC-143 Is anrooniua perfluorooGtanoate Ionic surfactant & ** Analyses ptsrforeed bys CHzM mn Quality Analytical Laboratories 2567 Fairlane Avenue Montgomery, AIL 36116 Method Detection UaH O.I ug/1 | Other analyses performed bys Du POnt Experimental Station 141 N Henry Clay Road wnrotngton. 06 19880-0301 Method Detection Unrit 1.0 ug/1 o g 1/31/92 <ji hews 1023 EID1162B4

AR226-2627 15 AR226-2627 RESULTS OF C8 SAHPLES PROM Dg'IH J993 5BOmro QATES SAMPLES ON THE SITE, Sample poinc C8 ia ppb ^fT-^^ -^/-2/ (r3 A B ff6 A B C D ?

Copies to: Material Tested E.

Ar226- 3295 - 80 AR226- 3298 Dupont-11603 -- `TRADE SECRET Study Title H-24678: Early Life-Stage Toxicity to Rainbow Trout, Oncorhynchus mykiss TEST GUIDELINES: U.S.

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