Exyeen ^J ^_^RREESSEEAAFRCH^Lpr.e_d_s-"eRReseseeaarrcchh.. .\, Proven Results.

AR226-2559 FILE No. 864 08/01 '01 13:01 ir>;DUDUPONTWILD. -8085-2 ' ^(SY * 123 * A 302 774 6474 07/30/01 (WE 2 16:03 0:02/08 N0;962 I.t^lwtf,1 VIW/ N^rt^ UNmro <TAT1(I ENVWROMNMIWNlMirTPARtO.

H^LancasterLaboratories ygr 2425 New Holland Pike Lancaster, PA 17601 AR226-2726 Analysis #0813FC - Revision 01 Supersedes Date: None "^ .

AR226-2910 FOR DP PONT USE ONLY Copies to Haskell E.

AR226-2925 FOR DU FONT USE ONLY REVISED REPORT Copies to E.

rr mM MM --M | HR RA6_ 3222 404 TRADE SECRET Study Title 'H-24768: Subchronic Toxicity WithOne9Ge0n-eDraaytiGoanvaRgeeprSotduudcytiinonRaEtvsaluations Volume dof 5 Laboratory Projct ID: DuPont 5990 ARaa6 - 3422 Duron TEST GUIDELINES: U.S.

TestingResults:Air-WatoPrartitioCnoefficie(nKtAw) for PFOS AIRIWATER PARTITION COEFFICIENT TEST SUBSTANCE Identity:Perfluorooctanseulfonatem;ay alsobe referretdoas PFOS or FC-95. (1-Octanesulfoniaccid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassium saltC,AS # 2795-39-3) Remarks: The testsubstance isa whitepowder.

4 I il PFOS: A 48-Hour StaticAcute ToxicityTeSt with the Cladoceran (Daphnia magna) ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

-- .. - -- .-.-.-.-.-.-.-..- .- .-.-.-..-....- - - hi,-,lhevels)fparticulatmeatter.The Environmenta IQualityBoard of Puerto izicohas statedthatCata fio(an industrializeadrea) has a historyof exceeding @atit)naAlmbient Air QualityStandards.The Hea lthDepartment of Puerto Rict)has reportedthe highestratesof respiratoriyllnessesand alltypesof ::inccrisn thismunicipalityU.sing theEPA standardsampling methodology, 1,)tasluspended particles(TSP) and particulatmeatter of lessthan 10 @Lm @P\110)were collectedinCatafioand Fajardo(controlarea)foreach season of the year.The particulatmeatterfrom the air filterasnd from reference ,tandardmaterial(SRM 1649. urban dust)Were extractedsequentiallywith threseolventosfdifferentpolaritieussing 24-hour SoxhietextractionT.he extractsobtained were testedfor cytotoxicitoyn human keratinocytesusing the NeutralRed Bioassay (NRB).

FC-17-R Submitted to: BIOSEARCH, INC.

,)'HAZLrm%CN LABCNDMMRIEB AA/ERICA, INC. 3301KINSMAN BLVD. p.o.BOX 45 MADISON, WISCONSIN 53707 Chemical& BioMedicalSciencesDivision PHONE (608)241-4471 TLX 703966HAZRAL MDS UD FINAL REPORT JUL, JANINE GLEASON MINNESOTA MINING & MANUFACTURING TOXICOLOGY SERVICES ST.

-@ l@@ 1@4 -I----m cov ArgoooCoomE@m THE DEVELOPMENT SERVICES COMPANY DraftReport 13-Week DietaryToxicityStudy withN-Methyl PerfluorooctanesulfonamiEdtohanol(N-MeFOSE, T-6314) inRats PREPARED FOR: 3M St.Paul,Minnesota COVANCE STUDY NUMBER: 6329-225 COVAW-C'E'."'

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*iha AR22E _ 3626 Eo TECHNICAL REPORT SUMMARY 70: TECHNICAL COMMUNICATIONS CENTER -- 201-2CN important =Hfmportpeintedcnbotsidesofape,mdtwcopes 9TCC.)