Covance Studies The attachedreportsummarizes the resultsfrom the assessment of mitochondrialbioenergeticosf hepaticmitochondriaisolatedfrom ratstreatedfor3 weeks with one of4 doses(pluscontrolo)f dietaryFC10.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES TEST SUBSI"N E (SCUD) Identity:A mixturecontaininpgerfluorooctanesulfonwahtiec,h may alsobe referredto as PFOS, FC-95, oras a component of FC-206 or L3243. (1-Octanesulfoniacid)(CAS # 2795-39-3).

AR 226 - 0797 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) EST SUBSTANCE Identity: Mixture containing Perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206A. (1Octanesulfonic acid) (CAS # 2795-39-3).

Experiment No.: Conducted At: Dates Conducted: Conducted By: Acute Oral Toxicity Screen with T-2574CoC in Albino Rats RECEIVED OCT - @ 1979 31 TOXICOLOGY 0979AR0037 Safety Evaluation Laboratory Riker Laboratoriest Inc-t St. paul, minnesota August 6, 1979 to September 6, 1979 i?

CENTRAL ANALYTICAL LABORATORY Report No. ---@219 -----------Date--- --May-- 16,- 1978 ------ Subject: F C-143 Analysis of IRDC 137-090 Samples Requestor: Dept.

AR 226- 050M ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as.

AR 286 -0296 SUMMARY FOR WORK PERFORMED FOR THE GERMAN GOVERNMENT AEXGTEINNCGYUIFSOHRINMGILFIOTAAMRYCTOEMCPHONUONLDOSGYFRAONMD MPURLOTCIPULREEMCOEMNPTAONNIEFSIRE TEST SUBSTANCE Identity: A mixture containing Perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-3017. (1Octanesulfonic acid) (CAS# 2795-39-3) Remarks: The 3M production lot number was not noted.

Copies to: E, I. du ?

28 Day Percutaneous Absorption Study with FC-95 in Albino Rabbits Experiment No.: Conducted At: Dates Conducted: Conducted BY: Reviewed BY: dc: M.

PHOTODEGRADATION (SOIL) TEST SUBSTANCE Identity:N-ethylperfluorooctanseulfonamidoethanolm;ay alsobe referredto as N-ETFOSE Alcoholor FM-3422. (1-Octanesulfonamide,N-ethyl1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-N-(2-hydroxyethyl@, CAS # 1691-99-2) Remarks: Materialisan off-whitew,axy solidof uncharacterizepdurity.

/0 Submitted to: BIOSEARCH, INC.

InternatioRneaslearcahndDevelopineCnotrporation SPONSOR: COMPOUND: SUBJECT: 3M Company FluoradS Fluorochemical FC-143 Ninety Day Subacute Rhesus Monkey Toxicity Study.

FE-RO ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: aPPceFirdOf,lSu1o,Dr1oE,o2Ac,t2s.aa3nl,et3,s,uF4lC,f4-o,9n59a,,t5e,o,6r,D63,EM7A,7S,saa8lm,t8p;,l8me-ahNyeop.atla2ds.eocba(fe1l-urOoecrftoea-rn,reescduoltfmoopnadis.c: with 2,2"iminobislethanol] (1:1), CAS # 70225-14-8) R(aepmparrokxism:atTeelsyt2s5am%ptleestissaubmsitxatnucree oafndth7e5te%stwastuebrs).tanAclevianlwuaetserreported relate to this mixture.

PHOTODEGRADATION (SOIL) AR12-032 TEST SUBSTANCE Identity: N-ethylperfiuorooctane sulfonamidoethanol; may also be referred to as N1.-1E,t2,F2O,S3,E3,A4l,c4o,h5o,l5,o6r,6F,M7-.37,482,28.,8-(h1e-pOtcatdaecnaefsiuulofroon-aNm-i(d2-eh,ydNr-oextyheytlh-yl)-, CAS # 1691-99-2) Remarks: Material is an off-white, waxy solid of uncharacterized purity.

2-A7 KV. ).:-7S AR226-3332 isra'uSticua; E.