New materials such as plastics, metals for which new uses are found, and new processes utilizing radiant energy may lead to physiologi cal disorders that do not become clinically evi dent until some years have elapsed.

from 1 I v ^ Kltf*S. hard- The West's leading painter-, de. *.

(MacGregor Lead)--------------------------------Mr.

Lead a) Proposed OSHA standard - should we comment?

If we assume that he has had no prior exposure to lead, he must have had a rather heavy exposure since entering upon hi3 present work.

K 0005216 Pot ent ial lead Po.lsontng - 2- June 22, 195^ 0 ' r c o m | | ke t h . .

His lead operator D.

\e^e a ^ < ooooz*^ OSHA HAZARD COMMUNICATION STANDARD CARCINOGEN LIST Sources: 29 CFR 1910; NTP 1983 Report, IARC Monographs 2-Acetylaminofluorene Acrylonitrile Actinomycin D Adriamycin Af latoxins 2-Aminoanthraquinone 4-Aminobiphenyl l-Amino-2-methylanthraquinone Amitrole Analgesic mixtures containing phenacetin o-Anisidine and o-anisidine hydrochloride Aramite Arsenic and certain arsenic compounds Asbestos Auramine manufacture Auramine (technical grade) Azathioprine Benz(a)anthracene Benzene Benzidine Benzo(b)fluoranthene Benzo(a)pyrene Benzotrichloride Beryllium and certain beryllium compounds N,N-bis(2-chloroethyl)-2-naphthylamine (chlornaphazine) Bischloroethyl nitrosourea (BCNU) Bis(chloromethyl)ether (BCME) and technical grade chloromethyl methyl ether (CMME) 1.4- Butanediol dimethanesulphonate (Myleran) Cadmium and certain cadmium compounds Carbon tetrachloride Certain combined chemotherapy for lymphomas Chlorambucil Chloroform bis-Chloromethyl ether Chlorophenols (occupational exposure to) Chromium and certain chrominum compounds Cisplatin Coke oven emissions Combined oral contraceptives Conjugated oestrogens p-Cresidine Cupferron (including MOPP) Cycasin Cyclophosphamide Dacarbazine DDT VVV 000022340 2.4- Diaminoanisole sulfate 1- - 2,4-Diaminotoluene Dibenz(a,h)acridine Dibenz(a,j)acridine Dibenz(a,h)anthracene 7H-Dibenzo(c,g)carbazole Dibenzo(a h)pyrene 1.2- Dibromo-3-chloropropane (DBCP) 1.2- Dibromoethane (EDB) 3.3- Dichlorobenzidene 3,3'-Dichlorobenzidine 1,2-Dichloroethane (EDC) Dienoestrol Diepoxybutane Diethyl sulphate Di(2-ethylhexyl)phthalate Diethylstilbestrol (DES) 3,3 *-Dimethoxybenzidine 4-Dimethylaminoazobenzene 3,3*-Dimethylbenzidine Dimethylcarbamoyl chloride Dimethyl sulfate 1.4- Dioxane Direct Black 38 Direct Blue 6 Direct Brown 95 (technical grade) Epichlorohydrin Ethinyloestradiol Ethylene dibromide Ethylene oxide Ethylene thiourea Ethyleneimine Formaldehyde Hematite underground mining Hexachlorobenz ene Hydrazine and hydrazine sulfate Hydrazobenzene Indeno(1,2,3-cd)pyrene Inorganic Arsenic Iron dextran complex Isopropyl alcohol manufacture (strong-acid process) Kepone (chlordecone) Lead acetate and lead phosphate Lindane and other hexachlorocyclohexane isomers Manufacture of magenta Melphalan Mestranol Methoxsalen with ultra-violet A therapy (PUVA) 4,4'-Methylenebis(2-chloroaniline) (MOCA) 4,4*-Methylenebis(n,n,-dimethyl)benzenamine Methyl chloromethyl ether Metronidazole Michler's ketone Mirex Mustard gas 2- - 0oozZ 2-Naphthiamine alpha-Naphthylamine Nickel and certain nickel compounds Nickel refining Nitrilotriacetic acid 4- Nitrobiphenyl 5- Nitro-o-anisidine Nitrofen Nitrogen mustard N-Nitrosodi-n-butylamine N-Nitrosodiethanolamine N-Nitrosodiethylamine N-Nitrosodimethylamine p-Nitrosodiphenylamine N-Nitrosodi-n-propylamine N-Nitroso-n-ethylurea N-Nitroso-n-methylurea N-Nitrosomethylvinylamine N-Nitrosomorpholine N-Nitrosonornicotine N-Nitrosopiperidine N-Nitrosopyrrolidine N-Nitrososarcosine Norethisterone 0estradiol-17B Oestrone Oxymetholone Phenacetin Phenazopyridine and phenazopyridine hydrochloride Phenytoin and sodium salt of phenytoin Phenoxyacetic acid herbicides (occupational exposure to) Polybrominated biphenyls (PBBs) Polychlorinated biphenyls (PCBs) Procarbazine and procarbazine hydrochloride Progesterone B-Propiolactone beta-Propiolactone Propylthiouracil Reserpine Saccharin Safrole Selenium sulfide Sequential oral contraceptives Soots, tars, and mineral oils Streptozotocin Sulfallate 2,3,7,8--Tetrachlorodibenzo-p-dioxin (TCDD) Thioacetamide Thiourea Thorium dioxide o-Toluidine and o-toluidine hydrochloride Toxaphene VVl/ V 000226*z Treosulphan 3- - 2,4,6-Trichlorophenol Tris(aziridinyl)-para-benzoquinone (Triaziquone) Tris(l-aziridinyl)phosphine sulfide Tris(2,3-dibromopropy1)phosphate Uracil mustard Urethane Vinyl chloride 4- - VVV 0000228*3

Picric sad is rapidly absorbed through the unbroken skin and even more rapidly through wounds, leading to headache, shiv ering, fever, and insomnia.

Hethods of Assastnent The methods employed to essess vorter exposures to asbestos ind subsequent physical changes associated with exposure, included chest x-rayt, pulswntry function tests, a resplratory/neurobehavloral questionnaire and, for Ml chemical products employees, blood samples for lead analysis.

A great many of the nation's leading manufacturers are users of AXIOM AND PARATEX AIR FILTERS.

Because its con tinuous research, high engineering stand ards and exclusive specialization have been consistently maintained, AAF equipment is used by leading companies in nearly every industry and is specified by leading architects and engineers for use in commercial and industrial air conditioning.

ELEMENTS OP INDUSTRIAL TOXICOLOGY Mercury and its compounds are not near ly so widely used as are lead compounds and consequently mercury poisoning is not so well known nor so often seen as is lead poi soning.

PURE PIO NEER WHITE, LEAD, puic linseed oil.

Such questions as whether total lead paint sales warrant spending more money and effort than are now being sunk in the job are not for me to decide.