3M Environmental Laboratory AR 1*26-0026 G) M ethod Extraction of Potassium Perfluorooctanesulfonate or other Fluorochemical Compounds from Liver for Analysis using HPLC - Electrospray/M ass Spectrometry Method Number: ETS-8-6.0 Author: Lisa Clemen, Robert Wynne Approved By: Laboratory Manager tGroup Leader --------- - a Technical Reviewer Adoption Date: o j l i h U x Revision Date: ~y ^ h < i Date Date Oilmh Date 1.0 Scope and Application 1.1 Scope: This method is for the extraction of potassium perfluorooctanesulfonate (PFOS) or other fluorochemical compounds from liver. 1.2 Applicable Compounds: Fluorochemical surfactants or other fluorinated compounds. 1.3 Matrices: Rabbit, rat, bovine, and monkey livers or other tissues as designated in the validation report.

A P 3 -2 6 -O IH Study Title Static Acute Toxicity of FX 3820 to the Daphnid, Daphnia aacna Authors Timothy J.

3M Medical Department Study: T6316.5 '*T f ORIGINAL Analytical Report: FACT TOX-013 LRN-U2095 sat-oW Study Title Analytical Study 2(N-Ethylperfluorooctane sulfonamido)-ethanol in Two Generation Rat Reproduction Analytical Laboratory Report Title Determination of the Presence and Concentration of PFOS, M556, PFOSAA, and PFOSA in the Liver and PFOS, M556, PFOSAA, PFOSA, and EtFOSE-OH in the Sera of CrLCD^BR VAF/Plus* Rats Exposed to EtFOSE-OH Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date At signing Performing Laboratories Sera Analyses Liver Analyses 3M Environmental Laboratory Building 2-3E-09, 935 Bush Avenue St Paul, MN 55106 Battelle Memorial Institute 505 King Avenue Columbus, OH 43201-2693 S Project Identification 3M Medical Department Study: T-6316.5 Argus In-Life Study: 418-009 Analytical Report: FACT TOX-013 3M Laboratory Request No.

TRP S bodies G e n e ra l D e scrip tio n o f T e lo m e r M a n u fa c tu rin g P r o c e s s Radio-labeled Material Synthesis Description A cute O ral Toxicity - Fixed D o se Ranqe-Findinq Oral Toxicity - Repeated D o se Subchronic Toxicity - 90-day G a v a g e Study M o u se M icronucleus Test Bacterial R e v e rse Mutation (A m es) Test Pharm acokinetics: Pilot Experim ents (1 4 C ) P hy sico-C hem ical Properties of 8 -2 Telom er Alcohol: Ultraviolet / Visible A bsorption Spectrum , V ap o r Pressure, W ater Solubility, Sorption Properties Hydrolytic Stability Adsorption / Desorption: Soil, Sedim ent and Slud qe (1 4 C ) A e ro b ic Biodegradation (cold material, scre e n in g study, m ethod developm ent, standards preparation) - D u Pont study Aerobic Biodeqradation (14C ) A tm o sp h e ric D egrad ation / indirect P h o to lysis in A ir lo n q R anqe Transport Properties (Air /W ater) A cute Aquatic Toxicity Studies (Fish, Daphnia, Alqae) Microbial R espiration Inhibition T est Terrestrial Toxicity Studies (Earthworm , Nem atode, Plants) C hronic Toxicity (21-day Daphnia) C a n a d ia n R e s e a r c h P ro q ra m - Y e a r 1 Interim R e p o rt (M a b u ry et al.)

/ K A 6 - \3V- 8-2 Telomer B Alcohol Repeated-Dose Oral Toxicity Range-Finding Study in Rats Work Request Number 13690 Service Code 1583 ic--ir --IOWP<rMmn-}. o o2orn cn vA Data Summary Summary The data in this document are from a range-finder study that was performed in order to set dose levels for a 90-day subchronic toxicity study with 8-2 Telomer B Alcohol.

AR226-1395 R a a6 - /3e!

AR226-1396 j ipp cc ; BTASU3MC0 0 1 E.

F F&F DEPARTMENT FC-143 DATA FEBRUARY. 1980 SITE NAME Weeks Exposure ________Blood Analysis___________ (approx.)

M a m - \H7*f RECEIVED Docket Number: f t R 'Sl'ZC*___________ __ Document Control Number: 3 ^ 3 o o o g > o 3 ^ Document Date: 3 - ty- <9 ^ ____________ DDocument Type: ______ ir ________ c<n O -- `T3 47- --H _ y X o cl pi o cn PsJ The document referenced above is claimed as confidential business information (CBt) under Section 14 of the Toxic Substances Control A ct (TSCA).

4ft a a 6 _ m 7 ^ i_ i.-- TSCA NCIC Notification Form for CBI Documents Docket Number: ______ ?

FLUogo foLH'hBtS Item 10: Monitoring - Fluoropolymers EPA Data Needs: (Draft 9-21-03) Data Need Manufacturing Releases LOI Commitment Data on releases to air, water, wastewater, landfill leachate Additional data EPA Proposal to Address Data Needs needs beyond LOI Manufacturing none Information on release of PFOA to air, water, wastewater, landfill leachate from manufacturing facilities Continued monitoring of releases Manufacturing Sites Concentration of PFOA in air, surface water, groundwater, soil, biota, wastewater, landfill leachate at manufacturing facilities Surface water, groundwater, wastewater, landfill leachate concentrations at manufacturing sites Limited biota data Modeling of PFOA in air Monitored concentrations of PFOA in air, soil, additional biota Screening level monitoring of PFOA in air to quantify concentration and extent Screening level monitoring of PFOA in biota (eg, fish and other aquatic species, plants, herbivores, avian, terrestrial species) at manufacturing facilities AR226-2341 EXP000280 - 1- EXP0QQ281 Item 10: Monitoring - Fluoropolymers EPA Data Needs: (Draft 9-21-03) Data Nee Off Site f om Manufaci itring Concentra ion of PFOA in i ir, surface wi ter, groundwa er, soil, and biota lown gradient fi om manufacti ing facilities LOI Commitment PFOA concentrations in surface water and groundwater from manufacturing sites Additional data needs beyond LOI Monitored concentrations of PFOA in air, soil, additional biota Limited biota data Modeling of air contamination EPA Proposal to Address Data Needs Monitoring of PFOA in air to quantify concentration and extent of off site contamination Additional groundwater monitoring, similar to Washington Works, to quantify PFOA in groundwater offsite contamination at additional manufacturing sites.

AR226-2367 Fi!

AR226-2453 ORGANICS ANALYSIS DATA SHEET laboratory Name : CH2M h i u .

AR226-2457 WWK FC-143 RESULTS DATESMPL SRCNAME ANALYTE RSLTMOD IRESULT PQL UNIT 22-Nov-91 LOWER POND 22-Nov-91 UPPER POND 27-Dec-91 LOWER POND 27-Dee-91 UPPER POND 15-Mar-94 LMW-2A 15-M ar-94.LMW-5B 15-Mar-94 LOWER POND 15-Mar-94 STREAM MN RD 15-Mar-94 UPPER POND 20Sep-94 LMW-2A 20-Sep-94 LMW-5B 20-Sep-94 LOWER POND 20-Sep"94 STREAM MN RD 2-Apr-96 001 POND OUTLET 2-Apr-96 002 POND OUTLET 2-Apr96 003 POND OUTLET 2-Apr-9e2-Apr-96 MWBG OUTFALL 004 2-Apr-96 OUTFALL 005 2~Apr-96 STREAM 1 2-Apr-96 STREAM 2 2-Apr-96 W IL L 331 2-Apr-96 WELL 336 9-Apr~96 DWNSTREAM 9-Apr-96 OUTLET 9-Apr-96 PROPBOUND 10-Apr-96 FBLK 10-Apr-96 MW-12 10-Apr96 MW-S 10*Apr-96 MW12A 10-Apr-96 MW13A 1Q-Apr-96 MW13A PC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 1 0J9 1.3 4.1 260 1200 730 0.5 4400 270 530 2200 0.9 61 72 20 < 0.1 13 39 7.2 14 0.52 0.48 25 86 9.9 < 0,1 < 0.1 0.97 < 0.1 11 8,2 MG/L MG/L MG/L MG/L ug/t ug/l ug/l ug/l ug/l ug/l ug/l ug/l ug/l 4 UG/L 4 UG/L 2 UG/L 0.1 UG/L 1 UG/L 2.5 UG/L 0.5 UG/L 1 UG/L 0.1 UG/L 0,1 UG/L 3 UG/L 20 UG/L 0.5 UG/L 0,1 UG/L 0.1 UG/L 0.1 UG/L 0.1 UG/L 1 UG/L 1 UG/L DATESMPL SRONAME ANALYTE RSLTMOD RESULT PQL UNIT 10-Apr-96 MW14 10-Apr-96 MW6A 11-Apr-96 FBLK 11-Apr-96 MW-4 11-Apr-96 MW-6 11-Apr-96 MW-9 11-Apr-96 WEST WELL 17-Apr96 FBLK 17-Apr-96 LMW-1 17-Apr-96 LMW-2A 17-Apr-96 LMW-7 17-Apr-96 LMW-8 FC-143 FC-143 FC-143 FC-143 FC-143 , FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 FC-143 < 0.1 0.19 < 0.1 39 15 0.14 3,7 < 0.1 1700 460 15 2200 0.1 UG/L 0.1 UG/L 0.1 UG/L 5 UG/L 2 UG/L 0.1 UG/L 0.5 UG/L 0.1 UG/L 200 UG/L 50 UG/L 2.5 UG/L 200 UG/L 66& .00M D EXD072360 17-Apr-96 LOWER POND FC-143 17-Apr-96 RT 33 STREAM SAMP FC-143 17-Apr-96 UPPER POND FC-143 18-Apr-96 MW-AJP FC-143 18-Apr-96 MW-MGM FC-143 18-Apr-96 MW-TWW FC-143 29-May-97 LOCAL LANDFILL W.

AR226-2760 FOR DU PONT USE ONLY E. 1. du jgjCjoxi.cologv8and^Induatria1 Medicine (see page * for composition) "bmittdby PomerTroducts Wanlngton Works 'u a Date rs of rHisr Completion: ^ lrUTMTTM ^ TRODUCTIOM to decermine ^ h e r the teat sample caJ** ss-s sss-issa'-Sa S e e s^iiir^nnot produce ^^ ^essential amino acid.