Document Gm9qXonebB3Xv5Oj49pM5ZpJv
AR226-2883
Copies
Material Tested
E. I. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine
Elkton Road, Newark, Delaware 19711
HASKELL LABORATORY REPORT NO. 55-80
Haskell No. lij197
Study Initiated/ Completed
8/27-10/5/79
Submitted hy
Chemicals, Dyes, and Pigments Jackson Laboratory
PRIMARY SKIN IRRITATION AND SENSITIZATION TEST ON GUINEA PIfiS
material was not a skin i r r i t a n ^ a s ^ e c e l v e d ^ W U h 3 BBle albitl 8"inea pl88 to test for skin Irritation potential. This
ico, z
- .05 - - *
^saline, 1 each eekPtginnng8r ; a s Zafdr the test l o r primarririitton!TM31 lnJectlon8 of `1 of a 1-OX solution in
ml of a 1002 and a 102 dispersion (vol/oi)^"at L r a t e r i i eSed8till!d8ttZa,:i0n
ZllttclTtime 9 unexposed guinea pigs (controls) of the same a g e ^ L v ^ d ^ ^ t c l l ^ L a 0?
aPP17ine and lightly rubbing in 0.05 ^ At the "
ompanv Sanitized, Does not contain TSC;
Results:
Concentration In distilled water i imary Irritation Test - 24 Hours
- 48 Hours Challenge Test - 24 Hours
- 48 Hours Sensitization Response Ratio***
at 1003! (as received) Concentration 0/10
Reactions on Intact Guinea Pig Skin
TO toiM lI'-'K fto i? wt. -T 6 5 T TO
io pii to*, wt. - eia I)
Itt- A'*- "------
kfcVKS fvb
9** Animals Final Avg. Wt
As Received
10Z
As Received
10Z
10 Neg. 10 Neg.
10 Neg. 10 Neg.
387 g 693 g)
10 Neg. 10 Neg.
10 Neg. 10 Neg.
9 Neg 9 Neg
9 Neg. 9 Neg.
Summary:I_
y - r e c e i v i d U U U Z ) orag-ff ta oispersioiriirirfSI dermatitis hazard is expected from handling this
produced no irritation when tested
hygiene practices
No unusual employed.
applied Initially ot o,, the nange Finding Results: "Test M1aterial`.
X fvpl/y); y*. 100"as received
50
25 5
^ " ` ' ' ....
....
toptotto fro. the w . ,, a t
Report by: Approved by:
3 neg. 3 neg. 3 neg.
JoiHnnES.r Henry
Technician
L> lCe^nnedy -- -- -- -- Chief. Acute Investigations Section
