Attachments to Letter to C.

M&S.6 _ 0637 If Charles Auer ' 05/16/2000 03:42 PM To: waweppner@mmm.com, dchakes1@mmm.com cc: Oscar Hernandez/DC/USEPA/US@EPA, Jennifer Seed/DC/USEPA/US, Barbara Leczynski/DC/USEPA/US@EPA, Karen Lannon/DC/USEPA/US@EPA Subject: PFOS items Following up on my phone call with Bill Weppner on May 15, I want to confirm a few points: 3M has arranged a discussion with the Commission of the EU on May 24 in Brussels to discuss PFOS.

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NORTHERN KENTUCKY OFFICE SUITE 340 1717 DIXIE HIGHWAY COVINGTON, KENTUCKY 41011-4704 606-331-2838 513-381-2838 FAX: 513-381-6613 Roberta.

AP.SlS.6 - Documents in TRP Database ^ ^ ^ ^ ^ ^ fslO TE^ C onnganjrjiub^ Source Title f Description Type of Data Available Phys.

a.a 6 -- TOXICITY TO TERRESTRIAL PLANTS TEST SUBSTANCE_______ Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The test substance is a white powder.

AR226-1519 30 September 2003 To: Mary F.

'rom 0#mfb j Reaiy an 10/04/2001 07 C2 PM rc a: Suoject Za*><J M Ruffc< Ag/DuPontigOuPont Rooeh F P'nchot/DEV'AE/D jPont@QuPont, M Ann Brici*y'ST8/0U3<i}DUP.

AR226-1750 PFOS: A PILOT REPRODUCTION STUDY WITH THE NORTHERN BOBWHITE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

Enclosure 5 Analytical Report Fluorochemical Characterization of Water and Sediment Samples Decatur Bakers Creek #2 - July 2003 (E03-0561) Exygen Research Laboratory Report No.

AR226-1894 Reproductive Effects of C8 James Dahlgren, MD Pamela Anderson-Mahoney, PhD November 2004 Reproductive Hormones Male C8 Workers Increased PFOA Levels Lower Testosterone Prolactin Higher Estrogen Prolactin if high alcohol intake Health Study in Residents Near a Large C8 Source Methods 301 fem ales and 296 m ales with docum ented P F O A -E xp o su re >. 0.05 ug/L in drinking w ater standardized questionnaire SEER prevalence data were used for com p arison Demographics for Residential Study Participants A ge C ategory 20 - 34 35 - 4 4 45 - 54 55 - 64 65 - 80 G ender M ale Fem ale R ace/E thnicity W hite African Am erican Others Education Level L e s s th a n 9 th g r a d e 9 1 1 grade 12 lh/ V o c a t i o n a l / S o m e C o lle g e College Graduate N o. 105 104 135 154 80 284 294 558 6 9 17 59 430 65 /o 18.17 17.99 23.36 26.64 13.84 49.13 50.87 97.38 1.05 1.57 2.98 10.33 75.31 1 1.38 Demographics for Residential Study Participants a w-- t i H T i ~-i'll-- nHiMTinrin iiiiMi iii 'iWMiii[ T M "T rrfigrtB n'iii[iririT r-T '-g ^ ,;^ No. ' B ody M ass Index U nderw eight (<23) A verage (23 - 28) O verw eight (>28 ) 106 190 276 % 18.53 33.22 48.25 Sm oking Status N ever smoked S m o k e d less th a n 15 y e a rs S m o k e d m o re th an 15 y ears 252 60.58 72 17.31 92 22.12 W ork H istory Plant 1 Plant 2 N o plant w ork 54 9.42 19 3.32 500 87.26 Reproductive Cancers in Residents Near a C8 Source CANCER TYPE U terin e/C ervical Breast Prostate Number of Cancers 9 5 9 Observed R ates3 (per 100,000) 3,061 1,701 3,169 Expected R atesb (per 100,000) 96 1,579 1633 PR 33.12 1.12 1.96 C lc 1 7 .0 3 -6 4 .4 1 * 0 .4 6 -2 .7 1 0 .9 8 -3 .9 2 Uterine/Cervical Cancer in Residents Near a C8 Source Age Category 20-29 30-39 40-49 50-59 60+ # of C a n ce rs 0 2 2 3 2 N P R P-value 34 0 - 38 56.40 0.0002 64 25.02 0.0008 84 34.18 0.00001 74 31.83 0.0005 Total 9 294 Age at Menopause in Residents Near a C8 Source Age By Category 38 U .S .

AR226-2004 W* *1 * February 8, 1988 /ZJ fO!

AR226-2112 Sample Date Range Concentration Range Action Level Industrial H ygiene 1/1/84 12/31/84 100% Sample Dt Sample# Duration Type Employee Name BTO: 08 TEFLON LOC: 701 FINE POWDER DRYER-EAST SIDE#2 1/8/84 46247 390 Z 1/13/84 46248 380 Z 3/11/84 46249 360 z 4/10/84 46250 395 z 5/7/84 46251 380 z 6/3/84 46252 380 z 7/2/84 46253 360 z 7/30/04 46254 360 z 8/24/84 46255 330 z 9/23/84 46256 420 z 10/21/84 46257 360 z 12/17/84 46258 370 z Pers Chemical C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 C-8/FC-143 Cone Unit Percent 82 MPB 146429%** 0.19 MPB 339% 0,31 MPB 55.4% OZI MPB 379% 0.47 MPB 839% 0.29 MPB 51.8% 0 .0 3 MPB 5.4% 0.26 MPB 509% QJ53 MPB 94.6% 0.62 MPB 110.7%** 056 MPB 64.3% 0.39 MPB 69.6% BTO: 08 TEFLON LOC : 702 FINE POWDER DRYER CONTROL ROOM (ALSO SEE TTF031 1/23/84 3656$ 345 z C-8/FC-143 1/27/84 36587 420 z C-8/FC-143 2/20/84 36568 360 z C-8/FC-143 3/17/84 36569 360 z C-8/FC-143 6/12/84 36570 385 z C-8/FC-143 7/8/84 36571 340 z C-8/PC-143 8/4/84 36572 420 z C-8/FC-143 10/2/84 36573 360 z ' C-8/FC-143 11/2484 36574 350 z C-8/FC-143 12/23/84 36575 340 z C-8/FC-143 0.62 MPB 0.51 MPB 038 MPB 0.37 MPB 0.S3 MPB 0.15 MPB 0.38 MPB 0.77 MPB 0.26 MPB 0.23 MPB <1 110.7%** 91.1% 679% 66.1% 94.6% 26.8% 67,9% 137.5%** 46.4% 41.1% BTO!

C harles J Zarzecki 02/24/2003 02:43 PM To: Catherine A Barton/AE/DuPont co: Subject: Slid e s Cathie, Here they are.

Katherine E.