TRADE SECRET AR226-3163 DuPont-4594 Study Title H-24159: Static, Acute, 96-Hour Screening Test with Pimephales promelas Laboratory Project ID: DuPont-4594 AUTHOR: Robert A.

TRADE SECRET Study Title H-24002: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Supplement No. 1 Laboratory Project ID: DuPont-2926 AR226-3216 AUTHOR: CarolPinlay,B.A.

PffYSICAL - CIffEIN/fICALPROPERTT-ES A Robust Summary, FinalReport, and Protocol on the physical-cbemicaplropertiesof perfluorooctanesulfonataere includedfor each of the followingparameters: PAR-KWTER DATE OF REPORT RESULTS ;MeltingPoint/MeltingPointRange Vapor Pressure n-Octanol/Water PartitionCoefficient Air-Water PartitionCoefficient Solubilitiyn ppre water SolubilityMeasurements on FC-95 2/24/99 5/5/99 2/11/00 3119/00 5/3/99 2/6/81 4000C 3.31x 104p (4@200C Not calculablet;hr" 0(<2xlO-) 570mg/l 1080mg/l phases The data presentedinthe study "SolubilitMyeasurements on FC-95," was determined by indirectmeasurement, not by actualanalysis.Therefore,the data isnot reliable.

3M SpecialtyMaterials 3M Center St.Paul,MN 55144-1000 651733 1100 June 8,2000 Dr.CharlesAuer Director Chemical ControlDivision OfficeofPollutionPreventionand Toxics United StatesEnvironmentalProtectioAngency 401 M Street,Southwest Room 403 EastTower (MailCode 7405) Washington,D.C. 20460 Re: InformationofPerfluorooctanoAicid & Salts- UEIP Form Dear Charlie: 3M isenclosingthecompleted"Use and ExposureInformationProfileo"r"UEIP" for perfluorooctanoiaccidand salts.

p. 1 A 9 aa6_ 36~s A preliminary list of publishe d references being considered in the update to the scienc e Prepared following the completion of the environmental and human health risk assessments of the 4 notified polymers .

3M Katherine E .

738 aM CCoorrppoorraatt IHenauthrPlhysHiycgsiene & CroorproaptsoerOcceupOcrupaationtaiontMedicneMedicne -- May 15,2000 32M0BCooxn3e22B0ung2025.02FY, (] 7 6615510i0y - I-A0R1s2060--00133778s F=al C0 v00(37 PRPeTcaeyreinc BStecoomo0R mis Ai 1 Document Processing Center (Mail Code 7407) Information Management Division UOfnfiitceedofStPaotlsluEtnivoinrPornemveennttailonPraontdecTtoixoincAsgency 4M0Str1 eet, SW : 72 35 9 Room 699 East Tower %( i A`Wtams:hiFnYgIton, D.

CChheemmoloiltitee HHaazzaarrddoouuss WWaassttee MMaanniifteesstt Form 21172 - C "Qe us oor DESCmRIPiTIOkN ey -- [aaF a[r ye r ][riioen|ce |99223 66007|1] US DOT DESCRIPTION EET Proper Shipping Name, Hazard Class, UN/NA No. a Re (maior chemical compor~ents) Phone I Blclg.

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3M Environmental Laboratory ARG-015T / fz Final Report- Analytical Study Single-Dose Intravenous Pharmacokinetic Study of T-6053 in Rabbits In-Vivo Study Reference Number: HWI#6329-136 Study Number: AMDT-010495.1 Test Substance: FC-99 (T-6053) `Name and Address of Sponsor: 3M SCD Division 367 Grove Street St.

Attachments to Letter to C.

3ff ARL26 1094 MR 54 376 The Society of the Plastics Industry, Inc.

ARR26-- 1106 ACUTE TOXICITY TO THE EARTHWORM (Eisenia fefide) TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3.4,4.5,5,6,6,7.7.8.8,8heptadecafiuoro-, potassium salt, CAS # 2795-39-3) R3eMmalortknsu:mbTehre2t1es7t.sSubasmtpalnecewiassastwohrietde upnodwedrera.mbSiaemnptlceonwdaistitoanksepnriforrotmo etelsetmiengn.taPluraintayldyesteesrtmeicnhendiqtouebse. 86.9% by LC/MS, 'H-HMR, *F-NMR and METHOD oMuettlhinoedd:inTthhee sOtrugdayniwzaatsiconofnodrucEtceodnuosmiincgCaooprpoetroactoilobnaasnedd Doenvperloocpemdeunrtes (TeOsEtCtDy)peG:uiSdteatliicn,eaNrtoi.fic2i0al7.soil substrate GLP: Yes Year Completed: 2002 Species: Eisenia fofida Analytical monitoring: Test substance concentrations in soil measured by LC/MS/MS at Days 0 and 14; in earthworm tissues after test termination.

So i, 30 Specialy Materials June 15, 2000 ri S3tM.PaCualneMrN SS144-1000 AR296 - 0577 77/7 / Mr.

H18636: Slide Review of pancreas lesions from DuPont APFO Study Date of Review: 28thNovember 2001-11-29 Reviewing Pathologists: Dr E E McConnell and Dr J R Foster Study No: HN-18636 Study Tide: Combined Chronic Toxicity/Oncogenicity Study with Linur-on, C8 and Wyl4,643.