Document M7b677Z6gZvBVyXKXg1KODNx

3M Corporate Toxicology and 3M Center, Building 0220-06-E-03 P. ~ Regulatory Services St. Paul, MN 55144-100 0 651 733 1773 Fax 3M Cert ified Mai l RECEIVED 0 , ~~,- i i" , C - ~~, zi 's ~r 07 JAN 16 AM 6 : 15 January 8, 2007 Document Processing Cente r EPA East - Room 6428 Attn : Section 8(e) Office of Pollution Prevention and Tcaafies US EPA 1200 Pennsylvania Avenue 14V4~` Washington DC 20460-0W F NO CBI RE : - . TSC'.CA ..8 (E), SUBSTANTIAL RISK NOTIG:ION : :PFHS and PFOS ; Supplemental to Sulf6nate-based Fluorochemicals, Docket Nos . 8EHQ-1180-374 ; 8EHQ-0381-0394 ; 8EHQ0598-373 Dear Sir/lviadam : In July of 2006 3M notified the EPA that preliminary data had been received from a study suggesting an effect of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed E3 Leiden transgenic mice in vivo . The final report for this study is enclosed . If there are questions, or if additional information is needed, please contact me at (651-7371374) . Sincerely, Deanna J. Luebker, MS, PhD 3M TSCA 8(e) Coordinator Enclosure C I/ i I l CONTAINS NO C61 E y o 7 0 1) (j Fri ii~ ir 30 1 l 18 .3