2.77 Pathology Associates International A Company of Science Applications temational Corporation ARGOS TL == S= e ar iaeComes PATHOLOGY REPORT (ANCILLARY STUDY) ELECTRON MICROSCOPIC EVALUATION OF LIVER AND LUNG AND LIGHT MICROSCOPIC EVALUATION OF LIVER IN CRL:CD@BR VAF/PLUS RATS) `ORAL (GAVAGE) PHARMACOKINETIC STUDY OF PFOS IN RATS CLIENT STUDY NUMBER 418-013 PAI STUDY NUMBER 99-11 (EM 99.39) Prepared by: James B.

ARZR6 -- 0815 ACTIVATED SLUDGE RESPIRATION INHIBITION TEST EST SUBSTANCE Identity: ArefmeirxrteudretocaonstaPiFnOiSng, pFeCr-f9l5u,oroorocatsanaescuolmfponoanteen,twohficFhC-m2a0y6CaEls.o b(1eOctanesulfonic acid) (CAS # 2795-393).

AR226-2081 WASHINGTON WORKS INDUSTRIAL HYGIENE REPORT PROM l-Jan-1994 TO l-May-1995 3-May-1995 Page 1 AREA: FLUOROCARBONS - HOMOPOLYMERS CHBMICAIi SAMPLE LOCATION *:CONTROL C-8/FC-143 003 FINE POWDER PACKOUT ROOM DATE: 27-Jan-1994 NOTEBOOK; TTF01.P398 DURATION: 370 COMC: <.03 MPB SAMPLE TYPE: P PERCENTAGE: 5% EMPLOYEE #04500 PERS CODE: 08PJ C-8/FC-143 008 P/S - FINE POWDER PACKOUT DATB: 27->Tan-1994 NOTEBOOK; TTF01,P399 DURATION: 375 SAMPLE TYPE: A CONC: <.03 MPB PERCENTAGE: 5% EMPLOYEE #00000 PERS CODE; C-8/PC-143 008 P/S - FINE POWDER PACKOUT DATE: 25-Aug-1994 NOTEBOOK; TTF01,P428 DURATION: 390 CONC: <.03 MPB SAMPLE TYPE: P PERCENTAGE: 5% EMPLOYEE #04632 PERS CODE; 08PJ C-8/FC-143 008 P/S - PINE POWDER PACKOUT DATE: 8-Mar-1995 NOTEBOOK: TTF01.P454 DURATION: 405 COMC: 0.02 MPB SAMPLE TYPE; P PERCENTAGE: 4% EMPLOYEE #04632 PERS CODE: 08P C-8/FC-143 008 P/S - FINE POWDER PACKOUT DATE: 8-Mar-1995 NOTEBOOK: TTFOl,P454 DURATION: 405 CONC: 0.02 MPB SAMPLE TYPE: P PERCENTAGE; 4% EMPLOYEE #04632 PERS CODE: 08PJ C-8/FC-143 017 ROOF AREA-GENERAL DATE: 28-Jan-1994 NOTEBOOK: TTF01,P404 DURATION: 380 CONC: <.03 MPB SAMPLE TYPE: A PERCENTAGE; 5% EMPLOYEE #00000 PERS CODE; C-8/PC-143 031 INSIDE P.P.

AR226-2215 ' Date Is based on testing conducted at the Washington Works site in September, 1996. b Particulata scavenging coefficients for liquid precipitation are from Figure 1-111n the EPA ISO Users Guide (Volume li).

Prof.

AR226-3036 Study Title Approximate Lethal Dose (ALD) of H-21333 in Rats Laboratory Project ID Haskell Laboratory Report No. 649-95 Author M.

TRADE SECRET AR226-3078 Study Title H-22762: Mutagenicity Testing in the Salmonella typhimuriwn Plate Incorporation Assay LABORATORY PROJECT ID: HL-1997-00676 AUTHOR: N.

AR226-3142 CONFIDENTIAL SPONSOR ElfAtochemS.A.

BIODEGRADATION (BOD/COD) TEST SUB -TANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredtoas PFOS, FC-95, or as a component ofFC-603EF. (1Octanesulfoniaccid)(CAS # 2795-39-3).

MICROBICS MICROTOX@ TOXICITY TEST TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredto as PFOS, FC-95, or as a component of FC-787 or FC787X. (1-Octanesulfoniaccid)(CAS # 2795-39-3).

A K 6 _ 02 So TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-603EF. (1Octanesulfonic acid) (CAS # 2795-39-3).

f t k 26 - 0 ^ 0 0 BIODEGRADATION (MANOMETRIC RESPIROMETRY - ANAEROBIC) TEST SUBSTANCE___________________________________________ Identity: A mixture containing perfluorooctanesulfonate;, which may also be referred to as PFOS, FC-95, or as a component of FC-3041. (1Octanesulfonic acid) (CAS # 2795-39-3).

Corporate Occupational Medicine 3M Center, Building 220-3W-05 St.

AR226-3018 t Study Title Repeated Dose Oral Toxicity: 14-Day Feeding Study with H-19683 in Male Mice Author John W.

3M MEDICAL DEPARTMENT TOXICOLOGY SERVICES cc: John Butenhoff From: MarvCase Subject: Covance Study 6329-222 Date: 27 July 1998 On 22 July 1998 when I was at Covance Madison, I reviewed the microscopic liver tissue sections of the monkeys on the 4-week oral rangefinder study of PFOS (Covance study 6329-222).