CUT itematCormspondence .Q AR16-OMu8l FaTmoDP.. 5F..

IN VITRO MICROBIOLOGICAL MUTAGENICITY OF 3M COMPANY'S COMPOUND T-3727 ASSAYS Final Report arch 1985 m By: Kathleen Moto, Midr6biologist Microbial Genetics Department and Edward S.

HAZLETON LABORATORIES AMERICA INC. 9 2 0 0 LEESBURG Tu ONPIKE VIENNA VIRGINIA 2 2 1BO U S A RAT TERATOLOGY STUDY T-3352 FINAL REPORT Submitted to 3M Comoanv St.

\iro~o2% RECc.

r] (ss) 2=3 R236-03/0 IN VITRO MICROBIOLOGICAL MUTAGENICITY ASSAYS OF 3M COMPANY'S COMPOUND T-3609 Final Report September 1984 By: C U t ) Debra E.

Pathology and Toxlcotogy RHcar Laboratories, Inc.

JEFFERSON M ED ICA L COLLEGE of THOMAS JEFFERSON UNIVERSITY Rl2fe-0530 Daniel Baugh Institute of Anatomy Department o f Anatomy Office of the Director and Chairman Philadelphia, 19107 (215) 928-7820 November 12, 1982 Dr.

A R B fc -0 5 6 ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, FC116, FC-126, FC-169, orFC-143.

AR226-3376 HASKELL LABORATORY Common Name: Ammonium Perfhiorooctanoate (C-8) Chemical Name: Octanoic add, pentadecafluoro-, ammonium salt CAS Registry No.: 3825-26-1 Chemical Structure: Physical Properties: OI cc f 3 - c f 2- c f2- c f2- c f2- c f2- c f 2 - - o -+n h 4 Form: Molecular W dght: Boiling Point: Melting Point: Density: White powder 431 Sublimes @ 110C -- -- Drinking Water Guideline (CEGW) 1 ug/L General Toxicity Ammonium perfluorooctanoate (C-8) has moderate acute oral toxicity with an LD50 in rats of 470 mg/kg 981b).

JEFFERSON MEDICAL COLLEGE of THONTAS JEFFERSON UNIVERSITY Daniel Baugh Instituteof Anatomy Department of Anatomy Office of the Directorand Chairman Philadelphia, 19107 (215) 928-7820 November 12, 1982 Dr.

To: Froin: Subject: Date: Study Files of Riker Experiments Nos. 0680TROO08 OGSOTROO10 0680TROO20 0681TROO95 0681TRO110 068ORROO18 L.

WATER SOLUBILITY TEST SUBSTANCE Identity:Perfluorooctanoiaccid,ammonium salt;may also be referredto as PFOA ammonium salt,Ammonium perfluorooctanoateF,C116, FC-1 26, FC-1 69, or FC-1 43.

ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonamtaey; alsobe referredtoas PFOS, FC-95,or as a component ofFC-203C and L-5440. (1-Octanesulfoniaccid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecapfoltuaosrsoi-u,m saltC,AS # 2795-39-3) Remarks: The 3M productionlotnumber was 501.

Experinent Nou: Conducted At: bates Conducted: Conducted By: Reviewed BY: Jute ocular Irritation Test with 7-349 in Albino Rabbits o88azB001L iSseae.fertpyauLlaB,bvoarlMauitanotnrieiosenost,LaabIonrcatory January 3, 1984 to January 10, 1984 BDooWs. avAarkroer, oItns S TSotxuidcyolDoigriescttor {zaatte KTSeanftorroTnoaxriiceroyl,log5ilst J Acute Toxicology lf we ar Xm.mL..

English edition (This document is only for reference.