Furthermore, there were no de layed evidences of injury as a consequence of the treatments with tetraethyl lead, ethylene dihroaide, etc.

It was suggested that the various sales department and refinery safety representatives would be interested in a paper concerning the handling and mixing of tetraethyl lead and also some comments concerning the cleaning of sales department tankage which has been used for the storage of Ethyl gasoline. .

It occurs to me that it might be well to investigate these substances for use in rubber protective equipment in connection with the handling of tetraethyl lead.

The train leaves at 8:55 A.M. and arrives in Saginaw at 11:52 A.M. '' This morning I contacted the men who are working directly with tetraethyl lead with the purpose of correct ing as far as possible the gross errors in handling so that you can devote your short time here to the less evident' hazards.; In checking through our work on the chlorphenols I find that vie have run some toxicities .studies on intra venous injections.

Calingaert's report On the effectiveness of the various reagents for neutralising tetraethyl lead. 1 must confess that it cornss as rather a blow to me that the slurry of bleaching lime is so ineffective even when used in great excess as was done on the sample, namely, 50 grams of lime to neutralise 1 gram of TEL.

Calingaert's report bn the effectiveness of the various reagents for neutralising tetraethyl lead. 1 must confess that it comes as rather a blow to me that the slurry of bleaching lime is so ineffective even when used in great excess as was done on the sample, namely, 50 grams of lime to neutralise 1 gram of TEL.

If it Is existent at all* We have been studying this problem over a period of years and we have failed to find laboratory evidence of the existence of lead absorption among men who have had the most severe and pro longed exposure through skin contact with leaded gasoline# Moreover our observations on experimental animals have proven beyond the shadow of a doubt that the lead absorption associated with skin contact with gasoline containing com raerclal amounts of tetraethyl lead i3 so slight that it can not he measured* It is possible that if one lived in a n _ environment free of lead, and If he at food that was lead free, it might be possible to demonstrate some measureable lead absorption as the result of gross and prolonged contact with leaded gasoline* It is quite certain now, I believe, that the magnitude of such absorption is very materially less than the absorption which results from eating a normal diet with Its normal lead content* With these facts in mind I can not fee l ,that there is any necessity or advisability in taking Mr.fBBJf out of his occupation which Involves the handling of leaded gasoline* This occupation is not a hazardous one* It has not been shown to Involve any lead absorption at all, and since his neurologic lesion is one which may only most doubtfully be attributed to lead ab sorption in any case, I do not feel that he should give up his occupation* Certainly not unless he has some other means of working and earning a living which is just as convenient andduat as lucrative as his present work* Of course is your patient and I shall not give him any such advice as I have indicated in this letter since it Is tipi to you to advise him in accordance with your best judgment* Therefore I am only stating the position I would take If he were my patient.

I as fulfilling the promise made In our telephone conversation of yesterday by sending you a series of articles which have to do with the problem of lead absorption In relation to leaded gasoline, as well as an article of my associated on gasoline dermatitis which I think will be of considerable Interest to you* I call, your attention specifically to the discussion and the citation of all the literature on the subject of Ethyl Gasoline is an article entitled An Appraisal of the Lead Hazards Associated tilth the Distri bution and Use of Gasoline Containing 'Tetraethyl Load Part 1 " which was published in the Journal of Industrial hygiene in March 193k* An article on the some subject hart IX gives rather crucial evidence, I boliovo, of the lack of load exposure associated with the handling of gasoline at filling stations*.

The fourth paragraph makes the categorical statement that lead poisoning from anti-knock gasoline containing tetraethyl lead Is one of the most!

The fourth paragraph makes the categorical statement that lead poisoning from anti-knock gasoline containing tetraethyl lead Is one of the most serious forms* I and my associates, as well as certain members of the staff of the Unit ed States Public Health Service, have been studying this problem from the point of view of the public health and the health of gasoline handlers In the United States over some period of years.

You will be interested in knowing that the Judge charged the Jury that there was no evidence that any of the Esso dispensed at the Rowe station during the times mentioned in the trial that had a greater concentration of tetraethyl lead than 3CC.

Tie realise fully that your rigid instructions regarding the careful handling of the concentrated tetraethyl lead are to be carried out to the letter, but in the preparation ox material for testing and in the actual testing operation our operator claims that he. cannot avoid inhaling to some degree the fumes from the fluid.

Tetraethyl......................

The fourth paragraph makes _the categorical statement that lead poisoning from anti-knock gasoline containing tetraethyl lead is one of the most serious forms, I and my associates, as well as certain members of the staff of the Unit ed States Public Health Service, have been studying this problem from the point of view of the public health and the health of gasoline handlers in the United States over some period of years, Every at tempt has been made to dtermine notoonly whether poisoning has resulted fJfoi this cause, but also whether there is any evidence that men so engaged are absorbing appreciable quahtities of lead.

That lead poisoning should]'till!