AR226-3188 DuPont-4739 TRADE SECRET Study Title H-24616: Subchronic Toxicity 90-Day Gavage Study in Rats with One-Generation Reproduction Evaluations Volume 5 of 5 Laboratory Project ID: DuPont-4739 TEST GUIDELINES: U.S.

AR226-3194 DuPont-6543 TRADE SECRET Study Title H-24949: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Laboratory Project ID: DuPont-6543 AUTHOR: Carol Finlay, B.A.

AR226-2496 ' M i S l i S ^ R B p a r t ^ ",'.

Corporate Health Physics Corporate occupationalMedicine Corporate Product Responsihility Corporate Toxicology 3M MedicalDepartinent 3M Center,220-2E-02 PO Box 33220 St.Paul,MN 55133-3220 651733 1110 FluorochemicalControlStudy Thisisa reportofa cross-sectiocnoarlrelatiaonalysiosfmedicalsurveillandcaeta collecteidn 1981 of Decaturchemicaland filmplantworkersand theirtotalorganic fluorinelevels.There were no statisticaslilgynificanctorrelationrseportedbetween SGOT, SGPT, GGT, alkalinpehosphataset,otalbilirubirne,d bloodcellsh,emoglobin and cholesterofloreithertheDecaturchemicalor filmplantworkers.The reportwas reviewedby Dr.

PFOS: A Flow-throu SaltwaterMysid (My en, CHRONIC TOXICITY TO THE SALTWATER MYSID TEST SUBSTANCE Identity:Perfluorooctanesulfonatmea;y alsobe referredtoas PFOS or FC-95. (1-Octanesulfoniaccid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassium saltC,AS # 2795-39-3) Remarks: The testsubstance isa whitepowder.

@77P7R1= PathologAyssociatelsnterriaatlion A Company ofScienceApplicatioInnsternatioCnoarlporation AnE"p"-O*MdCoxMwWy CollProliferaRteipoonrt 4-WeekCapsulTeoxiciSttyudyWithPerfluoroocStualnfeonic Acid PotassiumSalt(PFOS; T-6295)in Cynomoigus Monkeys Covance StudyNumber 6329-222 QUALITY ASSURANCE STATEMENT Thiscellproliferatipomnjecthas been inspectedand auditedby thePAI QualityAssurance Unit(OAU) as requiredby the Good LaboratoryPractice(GLP) regulationpsromulgatedby the U.S.Envimnmental ProtectioAngency.

(OHAZLEOCC3NLABORATAOMRERIICEA,SINC.. 9200 LEESBURG TURNF31KE, VIENNA.

ACUTE TOXICITY TO FISH TEST SUBSTANCE Identity:N -EthyplerfluorooctanesIufonamide; may alsobe referredto as U 1464, ETFOSA, ETPOSA, F-6309, or FX-1 2. (1Octanesulfonamide,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-N-ethylC-A,S # 4151-50-2) Remarks: Materialisa whitesolid.Sample purityand lotnumber were not recorded.

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:N-Ethylperfluorooctanesulfonamidmea;y alsobe referredtoas U1464, ETFOSA, ETPOSA, F-6309,or FX-12. (1Octanesulfonamide,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-N-ethylC-A,S # 4151-50-2) Remarks: Materialisa whitesolid.Sample purityand lotnumber were not recorded.

CORNINGHazlcton MUTAGENICITY TEST ON T- 6294 IN AN IN VIVO MOUSE NUCRONUCLEUS FINAL REPORT AU Hemalatha Murli,Ph.D.

Acute oral Toxicity Screen with T-3065COC in Albino Rats No.: Coliclucted At: I)ates Conducted:.

InternCaolrrespondence To: From: Subject: Date: C" ERCIAL CHEMICALS ANALYTICAL REPORT #346 E.

NOTOX Safety & Environmental Research &V.

0 13 r) IN VITRO MICROBIOLOGICAL MUTAGENICITY OF 3H COMPANY'S COMPOUND T-3609 ASSAYS Final Report September 1984 By: Debra E.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:Perfluorooctanesulfonylamido(ethyl)acemtaaytea;lsobe referredto as PFOSAA, FC-1 28 oras the major component of FC-1 27, FC-1 29, FC-1 09, or FC-1 09-X.