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AR226 _ 14 TH B 000161 - _. .

: 331SpectayMteras rSomeite AR296_ S12 3M "VIA HAND DELIVERY July 9, 2003 Document Control Office (7407M) ODfofcikceeotfARP-o2ll2u6tion Prevention and Toxics (OPPT) `EPA East, Room 6428 1201 Constitution Avenue, NW Washington, DC 20460 Phone: 202-564-8930 Attention: ODPPTock No.eAR-t 226 I' 82 om a) [Xt =z o2m8 @ Re: Information on Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and Related Compounds Dear Sir or Madam: `This continues 3M's voluntary submissionsofdata on perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and related compounds, as part ofour ongoing dialogue with EPA regarding perfluorochemicals.

Fomareniva TECHNICAL REPORT SUMMARY TO: TECHNICAL COMMUNICATIONS CENTER -- 201-20 (1mporan--t If porti prinonteotdh siodfpeapse,sndtwocopietso TCC.)

@HAZLETON wie eONS LN Soonsor: st. pant, Himesota FAL RevoRT 13-Meek Dietary ToxSitciutdyyTStiutdlye:with 180, Ammonium hn Perfluorooctanoate (CAS No. 3825-26-1) Guideline 82-1 Author: Matthew J.

<(email Correspondence ARWG-0 u%s3 ': ce: BR. oAhlnDeesosrun- Speocm.en,CheFml.uo-r2W2i3g-.65-C0hLemolite Center - k1-1 A.

AR 826 - O7T#3 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) EST SUBSTANCE Identity: A mixture containingperfiuorooctanesulfonate, `which may also be referred to as PFOS, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR 236 -- 075] TOXICITY TO AQUATIC PLANTS EST SUBSTANCE ---- Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR 226 -- 0780 MICROBIAL INHIBITION (DEHYDROGENASE ACTIVITY TEST) IESTSuesTANCE Identity: ArefmeirxrteudretocaonstaPiFnOiSng,pFeCr-f9i5u,oroorocatsanaescuolmfponoanteen,twohficFhC-m2a0y6aolrsoL-be 3243. (1-Octanesulfonic acid) (CAS # 2795-39-3).

AR 286 - 0790 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) IESTSU~B ~~ STANGE Identity: rAefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f9l5u,oroorocatsanaescuolmfponoanteen,twhoficFhC-m2a0y6aolrsoL-be 3243. (1-Octanesulfonic acid) (CAS# 2795-39-3).

AR 226 -- 0402 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity: rAefmeirxrteudretocaonstaPiFnOiSng, pFeCr-f9i5uo,roorocatsanaescuolmfponoanteen,twhoficFhC-m3a0y41a.lso(1b-e Octanesulfonic acid) (CAS # 2795-39-3). 3R0e4m1ar(kcsc :809-1T).he C3uMrrpernotdiuncftoiromnatloitonnuimndbiecratweassit2is30a0m.iTxthueretoesft6s%amPplFeOSis,F3C6-% doicteytlhyslulefnaeteg,ly0c.ol55b%utyslodetihuemr,la3u6r.yl0s6u%ifwaattee,ra,n1d20%.4S%ulttoolynletrfioaazomleer., 9% sodium cThhaerfaocltleorwiiznegdscounmcmeantrryataipoplniseosftiompaurmiitxiteusr.e Dwaittha imnacyomnpoltetaeclcyurately reflect the toxicofitthye fluorochemical component of the test sample.

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~AR226-/7/6 CANCER PREVALENCE IN SUBJECTS EXPOSED TO PERFLUOROOCTANONIC ACID (PFOA) Jam ors es Dahlgren MD', Ayman B enero Torabim MD'*', Raphael Warshaw', seston Harpreet Takbar MPH' i.