.

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PathologyAssociateslntemational A Company ofScienceApplicatioInnsternatioCnoarlporation AA Empbya&Owrad CaMwy SECOND DRAFT CELL PROLIFERATION REPORT 104-WEEK DIETARY PERFLUOROOCTANE CHRONIC TOXICITY AND CARCINOGENICITY STUDY WITH SULFONIC ACID POTASSIUM SALT (PFOS;T-6295) IN RATS COVANCE STUDY NUMBER 6329-183 PREPARED FOR: 3M TOXICOLOGY SERVICES BUILDING 220-2E-02,3M CENTER ST.

UnitCode 8308 1/14/99 2:54PM UROBILINOGEN, 48-HOUR, FECES ,SeneraIlnformaton FEE: $122.70 LABORATORY AREA: Porphydn-32/HC25 ANALYTIC TIME: I day DAY(S) TEST SET UP: Monday throughSaturday TIME OF DAY: Continuously LABORATORY HOURS: MAXIMUM LAB TIME: 3 days COMMENTS AND OTHER REJECTION: -cv 6%.

C-- 17-1?

,A Synthesis and Characterization of N-Ethyl FOSE-14 c December 11, 1980 Conducted at: During: Commercial Chemicals Division and Riker Laboratories, Inc. 3H St.

BIOSEARCH, INC. p.o.box 8598 philesdelphipae.nnsylvania19)01 t e Ie p k o n e 2 1 5 848-4499 Submitted to: Material: Sample Received: Date of Report: Test: Object of Test: Method of Test: 3M Company 3M Center St.

B 10 - T E S T 1810 FRONTAGE ROAD NORTHBROOK.

ACTIVATED SLUDGE RESPIRATION INHIBITION TEST TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may also be referredtoas PFOS, FC-95, or as a component ofFC-600. (1-Octanesulfonicacid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassium salt,CAS # 2795-39-3) Remarks: The 3M productionlotnumber was 628.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUB TANCE Identity:A mixturecontainingperfluorooctanesulfonawthei,ch may also be referredtoas PFOS, FC-95, or as a component of FC-600. (1-Octanesulfoniaccid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadegafluoro-p,otassium saltC,AS # 2795-39-3) Remarks: The 3M productionlotnumber was notnoted.

ACUTE TOXICITY TO FISH (MUMMICHOG) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredto as PFOS, FC-95, oras a component ofFC-780B. (1Octanesulfonicacid)(CAS # 2795-39-3).

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredto as PFOS, FC-95, or as a component of FX-3104. (1Octanesulfoniaccid)(CAS # 2795-39-3).

AN INVESTIGATION OF THE EFFECTS OF FLUOROCARBONS FATTY ACID-BINDING PROTEIN.

ARA26 - 3292 45 TRADE SECRET Study Tide F-25509: Repeated Dose Dermal Toxicity 28-Day Study in Male Rats AR 226_ 3293 DuPont 11763 TEST GUIDELINES: US.

ARAR_G 3u6T i --_ 73 000708 .