AR28-6 3267 1 AR 226 -- 3269 Determination of Ultravioletspectrum --| --_ DUPONT REPORT # 12734 [--------) vio SPECTRUM Test Guideline(s) aruthsorsisn, PhD. ay irc) ReymondE.

AR226-3351 ES Bioconcentration Screening of Perfluorinated Compounds Using Fathead Minnows Hoke, R., Turner, J.T., Gibson, W.R., Good, R.M., Green, J.W., and Buck, R.C. posto Introduction Perfluorinated compounds have been the focusofincreasing scrutiny by regulatory agencies and the industries that manufacture these compounds.

- r bE I \8S,FroAEn RliIss 1 " Attachment 2 Aezzg-/776- [ [ r I~ 1 | vc --_ i |- - | [ I te || Air Sampling Fluorochemical Report DuPont Washington Works -- Air Sampling Program Round 8 Exygen Research Report No.

CorporateHealth Physics CorporateOccupadonal Medicine CorporateProduct Responsibility Corporate Toxicology 3M Medical Department 3M Center,220-2E-02 PO Box 33220 St Pa4 MN 55133-3220 651733 1110 AnalysisofSelectedDecatur Employee Serum forSulfonicand Carboxylic ]Fluorochemicals This3M technicarleportanalyzedthe5 highestorganicfluorinceontaininDgecatur employee samplesand analyzedtheserum forperfluorooctanesulfonate, perfluorohexanesulfonaatned perfluorooctanoateI.n decreasingpercentfound, perfluorooctanesulfonactoentributebdetween 55 - 80%, perfluorooctanoatceontributed between 15 - 300/oand perfluorohexanesulfonactoentributed5 - 15% oftheorganic fluorineA.nalyticalmethods used were electroncaptureand microwave plasma detector. 3M T EOCHNICAL REPORT Report Number-. 7230 Date: October 4, 1979 TITLE: Analysis of Selected Decatur Employee serum for Sulfonic and carboxylic pluorocbealeals AE)THORs ABSTRACT: The precence of C and C. sulfonic acids was detected in certain blood samples using bo;g electron capture and microwave plasma detector methods.

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Lt ep 3M SRM Coerporate Toko and E3MmCaee, oiling 022006508 ARRZ6 . 362% feczpuen = ed a Peaieg 128 06FEIZY Aili on BEH9-0206- 15355 > E+ 3 on ime Document Processing Center eW[ ashaingion DC-- 20460-0001 Contain pyey cCay =2S Neca RE: TSESHCOA-SI(0E0)LSe1p3p4l6e5m8ntal Noss: Nemethylpefluoroosans slfonamidociano, Docket No.

: 5p AR 226 _ 10] MR U2 "Toxicology and Descriptive Biology Key Elements Acute Toxicity Data Exists x Repeated Dose Toxicity x Developmental Toxicity x Key Findings Ei - a2 Low to moderate toxicity: oral/dermal/inhalation Irritation potential defined Not a sensitizer Oral/dermal/inhalation rodent/non-rodent Liver primary target organ Potency defined Oral/inhalation rat/rabbit = = s 3% ~~ = Z- 58 8 Fetus not more sensitive than maternal Nanootmaaslsioecsiated with structural - "nntain NO CBI | Toxicology and Descriptive Biology Key Elements Reproductive Toxicity Genetic Toxicity Ecotoxicity - Acute Data Exists - x x Key Findings Reproductive organs not a target Functional reproduction not defined Point mutation - Ames negative Chromosomal effects- in vivo, in vitro - negative Not a genotoxic agent .

AR226-1403 ; A RD a ng dE 3: BERGASECSOCEMRGATE orn AR 86 -- 403 PDraotme:s DeTeplt:Not 0U1m-GAMpari-l19U9s1er 1A1N:0D7EaRmSWP ANDERS: WP@1SCOCVMZECDCIL 1eHRGATE TL ubject: Request for CEG for Ammonium Perfluorcoctanoate in Drinking Water 5a1te:BER0G4A/S01/91--C1S1OC:02:15Berg, Any 2++M:ResWe.ndPi.ngAnndoetresoonf, 03Jr/.28/91 15126 JeBrJEoCuTr: dRiesqcuusessitonf,or ICEaGm froerquAemsmtoinnigumyouPertfoluaoskrootchetanAEoLateComimnitDtreienkitnog Water theabHlaisskhella CLEaGb GfuoirdeA,mmo"nSieutmtiPnegrfAlcucoerpotoacbtlaenoEaxtpeosuirneDrLiinmkiitsnsg"WaItesre.sunePer ohatwattehre; vaalnude80w%e wtiollairgetsiwniclel abeCEGbasfeodr Co-n820h%asofaltroetaadly ibenetnakeesatlalbolciastheedd onasnidaelrsothreequaectsutailnghetahlatth tehfefeccotmsm.itttoeer,esoirdesntosneasdpjeaccieanlt gforououpr fWraosmhiHnasgkteolnl, orkcsa.

~ M226 _ 1412 ISST WELL ezy 5&/114//8587 . 151/ aalsees 1&0/241//8893 24//2270//9500 771390 10&//139//3500 REVISED TEST 411138/s81 7/24/51 8 31 ADJACENT WELL imgu-c e3/1i3/n91 4 DRINKING WaTgR 313/87 Blog 3 11/ 2/8& 12/98 eLpg 212 BLDG 212 S/ 8/89 Buda 212 S28 ON SITE samp ing c=9 ppg i2.l0s 1l3s ro i1s3 iillss 1s <<a0 E2.R5 sis 5.0 i1l.s3 w.6 <0.6 <0.6 <0.6 (3l.o0)5 .

AR R26 0698 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TESTSUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f9lu5oorrooacstaanecsoimfpoonnateen,twohfiFcCh-m20a1yAFa.lso(b1-e Octanesuifonic acid) (CAS# 2795-39-3).

ARRRG - O04 ACUTE TOXICITY TO FISH (RAINBOW TROUT) TEST SUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f8l5u,oroorocatsanaescuolmfponoanteen,twhoficFhC-m3a0y52a.ls(o1b-e Octanesulfonic acid) (CAS # 2795-39-3).

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3M Medical Department Study: T-6316.1 3M Medical Department Study: T-6316.1 Analytical Report: FACT-TOX-003 LRN-U2104 Analytical Report: FACT TOX-003 LRN-U2104 Study Title 104-Week Dietary Carcinogenicity Study with Narrow Range N-Ethyl PerfluorooctanesulfonamidoEthanol in Rats Analytical Laboratory Report Title Determination of the Presence and Concentration of PFOS, PFOSA, PFOSAA, EtFOSE-OH, M556, and PFOSEA in Serum and Liver Samples of Crl:CD@(SD)IGS BR Rats Exposed to N-Ethyl PerfluorooctanesulfonamidoEthanol Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date JuAntes0ig6n,in2g001 Performing Laboratories Liver and Serum Analyses JI 3M Environmental Laboratory Building 2-3E-09,935 Bush Avenue St.

Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendix F] Page 1 of 4 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats _____________________________________________________________________________________________________________________________________________________________ Appendix F: PFOS in Liver Samples Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendix F] Page 2 of 4 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats _____________________________________________________________________________________________________________________________________________________________ PFOS in Rat Liver [ppm] Animal No.

aM iREiCtLHY 651733 1110 AR22%--/3/5 SEP -2 F112: 58 en TEHR-0804. 03730: ALO 4TI T20 VIA EXPRESS MAIL BEHQ-20-377 Document Processing Center (7407M) EPA East - Room 6428 Attention: Section 8() Docket Officeof Pollution Prevention and Toxics UL.2S0.0 EPnevninreoynimveanntiaalAPvreontueec,tiNonWA.gency Washington, D.C. 20460 Re: PTeSrCflAuoSmescotcitoann8es)aloSnudptpeleDmoecnkteatlNNoso,tSiEcoHneO-1180:374 DeSei ant Mada Ce Uy.