CLIENT PRIVATE AF26-OI6I fk -- PROTOCOL TITLE: Range finding Cytotoxicity Assay of T-6292, T-6293, T-6294, T-6295 in R at Hepatocytes SRI Study No.

3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY Protocol for Study No.

ENVIRONMENTAL PHYSICAL/CHEMICAL, FATE, EFFECTS AND MONITORING STUDIES BACK TO COMPOUNDS STUDY TITLE LABORATORY OR DATE AUTHOR COMPLETED TYPE Physical/Chem ical Properties S o lu b ility o f P e rflu o ro -1 - o c ta n e s u lfo n y l F lu o rid e (P O S F ) in W a te r Environm ental Fate andTransport 3M Environm ental Lab 06/12/01 Robust sum m ary, final report Indirect Photolysis of G aseous Perfluorooctane Sulfonyl Fluoride (PO SF) by Fourier Transform Infrared (FTIR) Spectroscopy 3M Environm ental Lab 06/12/01 Robust sum m ary, final report

3M Environmental Laboratory R126-0005 M ethod A nalysis of Potassium Perfluorooctanesulfonate or O ther Fluorochemicals in Serum Extracts U sing H PLC-Electrospray/M ass Spectrometry Method Number: ETS-8-5.1 Author: Lisa Clemen, Robert Wynne Approved By: 'L l Laboratory Manager Adoption Date: 03/01/99 Revision Date: <V / 2 C / Date Group Leader Technical Reviewer Date dh i / m Date 1.0 S c o p e a n d A p p l ic a t io n __________________________________________________________________ 1.1 Scope: This method describes the analysis of serum extracts for fluorochemical surfactants using HPLC-electrospray/mass spectrometry. 1.2 Applicable Compounds: Fluorochemical surfactants or other fluorinated compounds, or other ionizable compounds. 1.3 Matrices: Rabbit, rat, bovine, monkey, and human serum, or other fluids as designated in the validation report.

Corporate Health Physics Corporate Occupational Medicine Corporate Product Responsibility Corporate Toxicology 3M Medical Department 3M Center, 220-2E-02 PO Box 33220 St.

A R 1 U -0 1 5 I Laboratory Report Interim Report of Preliminary Data for 26 Week Capsule Toxicology Study with PFOS in Cynomolgus Monkeys Laboratory Report No.

ACUTE TO XIC ITY TO FISH (M UM MICHOG) TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-780. (1Octanesulfonic acid) (CAS # 2795-39-3).

Northwest Bioanalytical A6_ IAH Study No.

Proven Results

Wildlife International, Ltd. -1 - Project Number 454A -106 PFOS: A 96-HOUR SHELL DEPOSITION TEST W ITH THE EASTERN OYSTER (Crassostrea virginica) ADDENDUM WILDLIFE INTERNATIONAL, LTD.

Group Summary P Generation Group Group 1 Group II Group III Group IV Group V NUMBER OF DAYS OF DATA COLLECTION NUMBER OF DAYS IN ESTRUS % OF DAYS IN ESTRUS 21 g 43% 21 8 41% 21 9 42% 21 8 39% 21 9 42% NUMBER OF DAYS IN % OF DAYS DIESTRUS IN DIESTRUS NUMBER OF % OF DAYS DAYS IN IN PROESTRUS PROESTRUS 9 41% 9 45% 9 45% 10 45% 9 43% 3 16% 3 14% 3 13% 3 15% 3 15% "N" FOR MEAN CYCLE MEAN CYCLE NUMBER OF LENGTH LENGTH CYCLES 30 4.3 4.6 30 4.0 4.6 28 4.1 4.3 30 4.3 4.4 29 4.1 4.6 P Generation nimal I 13801 13802 13803 13804 13805 13806 13807 13808 13809 13810 13811 13812 13813 13814 13815 13816 13817 13818 13819 13820 13821 13822 13823 13824 13825 13826 13827 13828 13829 13830 13831 13832 13833 13834 13835 13836 13837 13838 13839 13840 13841 13842 13843 13844 13845 13846 13847 13848 13849 13850 Group 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 MEAN CYCLE LENGTH 3.75 3.20 3.75 3.67 3.75 5.33 4.00 4.25 4.25 4.25 4.50 9.00 4.00 5.00 5.00 4.33 4.00 4.00 4.00 4.00 4.25 4.00 4.00 3.40 4.67 3.75 4.25 3.75 4.00 4.00 3.67 4.25 4.00 3.75 4.00 4.00 4.00 4.50 3.75 4.33 3.75 4.00 4.25 3.75 4.00 4.00 4.00 4.00 4.00 4.25 NUMBER OF CYCLES 5.00 6.00 5.00 4.00 5.00 3.00 5.00 4.00 5.00 5.00 4.00 2.00 5.00 4.00 4.00 5.00 5.00 5.00 5.00 4.00 5.00 5.00 5.00 6.00 5.00 5.00 5.00 4.00 4.00 5.00 5.00 5.00 5.00 5.00 5.00 2.00 5.00 2.00 5.00 5.00 4.00 4.00 5.00 4.00 4.00 5.00 4.00 5.00 5.00 6.00 13851 13852 13853 13854 13855 13856 13857 13858 13859 13860 13861 13862 13863 13864 13865 13866 13867 13868 13869 13870 13871 13872 13873 13874 13875 13876 13877 13878 13879 13880 13881 13882 13883 13884 13885 13886 13887 13888 13889 13890 13891 13892 13893 13894 13895 13896 13897 13898 13899 13900 13901 13902 CO CO CO P Generation 2 3.25 6.00 2 3.75 5.00 2 4.00 4.00 2 4.00 5.00 2 3.75 5.00 2 3.75 4.00 2 4.50 4.00 2 4.00 5.00 2 3.80 5.00 2 4.25 5.00 3 5.00 3.00 3 3.75 5.00 3 4.00 5.00 3 4.67 4.00 3 4.00 4.00 3 4.67 3.00 3 4.00 5.00 3 3.75 5.00 3 4.00 5.00 3 4.00 4.00 3 3.75 5.00 3 3.75 5.00 3 4.00 5.00 3 5.00 3.00 3 4.00 4.00 3 3.75 4.00 3 4.25 4.00 3 4.25 5.00 3 4.00 6.00 3 4.00 4.00 3 5.00 4.00 3 4.00 5.00 3 3.75 5.00 4.00 5.00 #DIV/0!

EXHIBIT 1 Table A.

i AR226-2150 Roger J .

AR226-2570 [Andrew S Hartten To: Mary A Kaiser/AE/DuPont@DuPont cc: John R Bowman/AE/DuPont@DuPont Subject: Sampling Program Mary, l6/0T/20di'Q5T02 PM t I'm a little concerned about the decision to contract Battellle to provide sampling services related to the Consent Order.

METHODS AND MATERIALS This inv estig atio n was perfformed a t the aquatic toxicology l s a u b s o c reapt.toirbyi l -if ity Bi o o f nomi rain cs, bow |int rco.u, t Wareham, (Salmo`g M ai as rd sach neri us ) e t tt o s.