Test requestor: DuPont KX.

(In addition, Sakr et al. (2007) reported that serum calcium, iron, potassium, and the enzyme lactate dehydrogenase were significantly associated with serum PFOA among workers at the DuPont Washington Works facility, though the direction of those associations was not given.

RAG -- 3245 hid 5o [ 0 uyD Orr Gy aE ge So--pans Gmpswiymt M2o2aDw6ur-es e3ss2s45 _ "TRADE SECRET Study Tide H-24678: Subchronic Toxicity 90-Day Oral Gavage Study in Rats Volume 3 of 4 Laboratory Project ID: DuPont-6554 `TEST GUIDELINES: U.S.

(In addition, Sakr et al. (2007) reported that serum calcium, iron, potassium, and the enzyme lactate dehydrogenase were significantly associated with serum PFOA among workers at the DuPont Washington Works facility, though the direction o f those associations was not given.

On the other toxicology sses, fous he question and hen ge a precise answer jst saywi the Dupre Known issues, focus the question and then give a precise answer or just stay with the Dupont "known 1 be causa formationof he more Genarsl salty SeusAL to be caused" formulation of the more general safety lissuels~]. 11999955..00000011 EExxhhiibbiitt 11999955 State of Minnesota v. 3M Co., Court File No. 27-CV-10-28862 33MM_MMNNO011552255883333 PPllaassttiiccss EEuurrooppee -- QQ&&AA OONN PPFFOOAA 2255 JJaann 22000055 Key messages processing aid in the manufacture of some fluoropolymers. t PPFFOOAA iiss aa mmaann--mmaaddee ssuurrffaaccttaanntt ((ddeetteerrggeenntt--lliikkee mmaatteerriiaall)) uusseedd aass aann eesssseennttiiaall processing aid in the manufacture of some fluoropolymers.

(FFFC) -- Current members are: Ansul, Atofina, Buckeye, Chemguard, Dynax, DuPont, Kidde --_-- eee EFRC aFfrlagmhum _-- Eoatcion 8 Fire Fighting Foam Coalition + FFFC was formed to represent the AFFF industry's interests on issues related to the environmental acceptability of fire fighting foams + The coalition provides a focal point for industry science reviews, development of industry positions, and interactions with the EPA and other relevant organizations Se ------------ EEC fFHrooeamhn A -------- Coateion 9 Fire Fighting Foam Coalition FFFC will: + Support users of AFFF by serving as a single source for accurate, balanced information on environment related questions Establish a dialog with EPA and other regulatory authorities to ensure that accurate information about PFOS alternatives, including telomer-based products, is disseminated into the marketplace eeeeeeeee 36 eec EFfGlaaoTneimon Fire Fighting Foam Coalition FFFC will: + Participate in EPA's ongoing review of PFOA and telomers as they relate to AFFF + Continue a dialog with DoD to ensure that the differences between AFFF agents are well understood + Serve as a focal point for information on the development and approval of environmentally acceptable and effective alternatives --_-- === Ces FEC mfFroleaman Conteion 3] Managing The Use Of AFFF + Use Alternative Training Foam Agents + Use Alternative Testing Foam Agents + Minimize Discharges --_-- ec fhm ------------------ alion FFFC Position On AFFF + AFFF Has A Proven Track-Record of Superior Performance on Class B Fires -- Lower Critical Application Rate Faster Knockdown - Superior Burnback Resist

ORIGmi DOCS NOT CONTAIN CBI July 20, 2010 Via Federal Express pf'p I0 JL2 OE W - h h DuPont Haskell Global Centers for Health and Environmental Sciences 1090 Elkton Road, P.O.

The internal standards usedwere a dual labeled PFOS where two 0 molecules were included in the sulfonate group (intemal standard, >99% purity, synthesized by Research Triangle Institute, Research Triangle Park, NC) and a dual labeled PFOA molecule, where the carboxyl and alpha carbons were labeled with "C stable isotope (greater than 97%, provided by DuPont, `Wilmington, DE).

Does not contain TSCA CSI 2 Title: Analysis of Residual Solvent (Ethanol) i (non-GLP study) Commissioned by: DuPont KK 1-8-1 Shimo-meguro, Meguro-ku, Tokyo 153-0064 3 Testing Facility: Kurume Laboratory Chemicals Evaluation and Research Institute, Japan (CERI) 19-14 Chuo-machi, Kurume-shi, Fukuoka Prefecture 830-0023 Purpose of Study: To determine the level of ethanol remaining in Forafac 1157.

Viton is a registered trademark for fluoroelastomers by DuPont Performance Elastomers, USA.

Chemical & Material Risk Management Directorate Office of the Under Secretary of Defense for Acquisition, Technology & Chemical & Material Emergir.^, ...

AR226-3119 TRADE SECRET Study Title H-23745: Local Lymph Node Assay (LLNA) Laboratory Project ID: DuPont-2642 AUTHOR: Gregory S.

ORIGINAL DOCS NOT CONTAIN CBI 3 S 8 \\3 3 July 15, 2010 i- OJUL 19 fft`jM'1 09 DuPont Haskell Global Centers for Health and Environmental Sciences 1090 Elkton Road, P.O.

I , DUPONT DE NEMOURS & COMPANY NEWARK, DELAWARE A cuue\ t o x ic it y o f 8231 to rainbow t r o u t ^(Salmo g a ir d n r i) .

Flux Calculation Groundwater Investigation Steering Team (GIST) GIST Offsite Summary-3 Landf Item Sitel Site 2 S GIST Offsite Sample 1-mile 1-mile 2 # Off-site Samples 30 53 Offsite PFOA Range ND-0.636 ND-0.974 N (Ppb) Offsite PFOA Mean 0.04 0.185 (Ppb) Landfills-Overall Impression Landfills are regulated by state permits Permits require: - Engineering controls - Monitoring plans Our experience demonstrates: - Engineering controls are effective for PFO - The monitoring conducted indicates minim PFOA contribution to the environment Actions The other Fluoropolymer LOI signatori will compare the DuPont data with thei industrial landfill data in order to devel an understanding of the contribution of other landfills to PFOA environmental loadings ECA Technical Subgroup Monitoring Soil Sampling Summary Goal for Today Understand the significance of soil sampling in characterizing the overall manufacturing contribution to PFOA le in the environment CATT Defined Soil Ingestio Risk Based Concentration 240 mg APFO/kg soil or 240,000 ug/kg Based on typical child/adult exposure through ingestion scenario Soil Exposure Scenario Exposure assessments for soil typically consi the topmost 1 to 2 feet of the soil column whe accidental ingestion may occur.