DuPont manufacturing facility located in Parkersburg, West Virginia. 2.

Table 2 Chemical Resistance of Typical Plant Materials Chemical resistance of equipment materials at 20 C 1,2,3) Solvent NBR Non-PFAS EPDM VMQ (Silikon) FKM (Viton) PFAS FFKM (Kalrez) PTFE FEP PFA Tetrahydrofuran Methanol Acetylene Acetone 1) Literature sources: Dechema material table; BAM List 2021 (Bundesamt fr Materialprfung; Requirements for tanks for the transport of dangerous goods); Corrosion Data II; DuPont Brochure; SIS handbook 149; Knowledge gained during long production history 2) Conclusion: resistant partially resistant non-resistant unknown 3) Overview of typical available materials: NBR: nitrile butadiene rubber; EPDM: ethylene propylene diene monomer rubber; VMQ: vinyl methyl silicone; FKM: fluorine kautschuk material; FFKM: fluorinated fluorine kautschuk material; PTFE: polytetrafluoroethylene; FEP: fluorinated ethylene propylene; PFA: Perfluoroalkoxy alkanes Examples for production equipment where fluoropolymers and fluor-elastomers are used in manufacturing of levonorgestrel are stirred-tank reactors, piping, pumps, hoses, and gaskets.

TRADE SECRET Study Title H-23269: SKIN IRRITATION TEST IN RABBITS LABORATORY PROJECT ID: DuPONT-1139 AR226-3099 AUTHOR: Carol Finlay, B.A.

Participants were also required to have residential water service provided by Lubeck Public Service District or Little Hocking Water Association, to have not reported growing vegetables at home at the time of the C8 Health Project, to have never been employed by DuPont Company, to not have had any other job working worked with PFOA since 2000, and to have signed a consent form allowing C8 Health Project data to be shared with the C8 Science Panel.

Participants were also required to have residential water service provided by Lubeck Public Service District or Little Hocking Water Association, to have not reported growing vegetables at home at the time o f the C8 Health Project, to have never been employed by DuPont Company, to not have had any other job working worked with PFOA since 2000, and to have signed a consent form allowing C8 Health Project data to be shared with the C8 Science Panel.

A vivid illustration of this approach is captured in "The Weinberg Memo" [1]: DUPONT MUST SHAPE THE DEBATE AT ALL LEVELS [...]

Robertson, PE Principal Engineer U R S Diamond DuPont Corporate Remediation Group B M P 1 9 - 1238 4417 Lancaster Pike Wilmington, D E 19880-0019 (302) 892-8280 direct w/voice mail (302) 892-1533 william.b.robertson@usa.dupont.com william b robertson@urscorp.com This communication is for use by the intended recipient and contains information that may be Privileged, confidential or copyrighted under applicable law.

Associate members are DuPont, Gujarat Fluorochemicals, Honeywell and HE Plastics.

AR 226 - 346L 8 IN BLO - Histone 1 ~ 1879 c-8 fod in blood of Dupont workers. 1978 Informed by 3M that C-8 is found in the blood of exposed workers and persists for a long time. 1980 Workers with blood C-8 found to have normal liver function. 1981 Birth defects scare - additional sampling. 1982 Blood program continues on voluntary basis - no trends noted. 1990 Formal review of blood data. 1985 First Syear "snapshot. 1993 Journal Of Occupational Medicine study of 3H workers. 2 000655 as mem maemo ac: eo "3 s1000 owtToRn THIS 15 THE ONLY REASIRE VE WAVE GF TOTAL ENPLOVEE EXPOSURE Prostens GIOPERSISTENCE WARES DATA INTERPRETATION DIFFICULT suru 1s stv LEKIHY MUALYSISISRUNBYORLY ONELAB NO AEL 000656 WASHINGTON WORKS VOLUBLNOOTDTAESRTINYG 0 - <1 ppm 1-<3 pm >3 ppm TOTAL 1993 1994 9 47 2 5 2 1 13 53 |~ MNosystematic comparison with air sampling is possible.

(29 DuPont Science Strategy: PFOA_______ ___________________________ ____________________ ______________________________ September 15, 2006 NAME (Please print clearly) O R G A N IZ A T IO N TELEPHONE # E-M AIL ADDRESS i^ u sszll 1 peb 'IW k Ik lX n jf' 2 >aPcrtvA sW ssts.K .kcA ^ 'O ^ lu ^ Vi<s. 366-6053 i^cJ^rk- b-rx>sseil<?

ORIGINAL 339120 October 29, 2010 DuPont Haskell Global Centers for Health and Environmental Sciences 1090 Elkton Road, P.O.

AR226-2655 -& 01 AR226-2655 ISC Modeling Methodology and Results Introduction This report summarizes dispersion modeling that was completed for the DuPont Washington Works facility to demonstrate that the emission limits included in the form R13 permits (815E, 1353B, 1953B, and 2365C) comply with the C-8 assessment oftoxicity (CAT) recommended airborne screening level of 1.0 ug/m3 at the property line fence.

C-8 found in blood of DuPont workers.

At 200 pg/L fortification o f adapted bacterial culture from sludge, spike recoveries were 69-81% (DuPont EMSE Report No. 15-03, Accelerated Biodegradation of 8-2 telomer B alcohol).

Environmental Protection Agency 1201 Constitution Avenue, NW Washington, D .C . 20004-330 2 Phone : 202-564-825 7 RE : AR-226 : Letter dated March 7, 2007 from DuPont (H .