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A R I I M g kbw-2/3/98 Effect of N -Alkyl Perfluorooctylsulfonamides on M itochondrial Bioenergetics In Vitro Kendall B.

AR17J6-033I Feces3MMPerMothtoEocdDoDIlCfeoAvreLSlotDpumEdyPeAnNtRoM.TTeMt-Da6Eb3eNor1il6Tvis.a,1mtC7iv,OSeTtsRu-.6dP2yO9fR5o.A2r1PT,eETrf-T7luO1o3Xr2oI.o3C;cOtSaLTnOe-4sG1ulYfonate SFfTetlhcuuieodssrysimtnuOeedbtAyajebnicsoatlldiiyvteteeis:ciaganlnaCelydhsetiosm. gisetnryerTaeteamspteociumseenfsofrodretvheelo3pMmEenntvairnodnvmaelindtaatliLonabaomraetothroyd of Research O ient: 33SMMainCSt pPeenacuteilar,l,tMyBNuCihl5de5imn1gi4c42a3ls6Division Sponsor: 33SMMainSCtpPeenacutiealr,l,tMyBCNuihl5de5min1ig4c4a2l3s6Division Study Location: 33SMMainSCt tPernaatuteelgr,,iMcBTNuiol5dx5iinc1go4l42o7g0y-L3Sab-0o6rartooorym SB314 Study Director: PA33TSMMhaoni.xd:nMiCrt6cePo5ewenal1dout-Mieg5clr,y7a.

AR226-0980 has actually been processed as 8EHQ-0101-0373 but is included here in FYI-0101-1378 as well as it was received as an attachment to this FYI.

V A A A 6 _ U f-U i Distribution H a t EFFECT OF FLUOROCARBON DISPERSING AGENTS ON THE LIVERS OF RATS AND DOQS Medical Research Project Nos.

AP'.a _ ih-1$ 000227 INTEROFFICE MEMORANDUM Date* From I Depts Tel Noi 12-Apr-1990 02*45pm A N T H O N Y J.

0- o V) S o o O'- o oo oo o Vo V) N o Q AJP001214 EID080614 J / z e - K & s m u g - r t /j f t t e . l e ^ l. s o L2 O-- OO CV) o V) "N* \ s * s3 r\j S3 i Oo- d Q Oj-Q <* Oo CT] 1 U 55 Cjs <o d ) lo S Q h o S <> N co % O *0 Q 0 * O O & CCsio.

Attachment 2 * * 6 -/7 7 6 -e.

3M Medical Department Study: T-6295.4 Analytical Report: FACT TOX-002 LRN-U2121 Study Title 104-Week Dietary Chronic Toxicity Study with Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) in Rats (Covance Study No.: 6329-183) Analytical Laboratory Report Title Determination of the Presence and Concentration of Perfluorooctanesulfonate (PFOS) in Liver and Serum Specimens of Crl:CD(SD) IGS BR Rats Exposed to Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date At signing Performing Laboratories Liver and Serum Analyses 3M Environmental Laboratory Building 2-3E-09, 935 Bush Avenue St.

^ 036-0537 TOXICITY TO AQUATIC PLANTS (E.G., ALGAE) TEST SUBSTANCE Identity: Perfluorooctylsulfonate, didecyldimethylammonium salt; may also be referred to as Fluoroalkyl ammonium derivative. [1Decaminium, N-decyl-N,N-dimethyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1octanesulfonic acid (1:1), CAS # 251099-16-8] Remarks: The 3M production lot number was Lot 1.

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________________________________________________Name_____________________________________ Thompson Collins Watkins Smith Coneentratlons are from the deposition modeling runs, and Include wet and dry depletion due to deposition I AR226-2245 EDD0079976 C o o rd in a te s Particulate Deposition (g /m 3/ y r ) Vapor Deposition (q /m V ) Total Deposition (q /m V ) 445213E 4346090N 443141E 4345753N 443223E 4345847N 443254E 4345888N 0.00098 0.00179 0.00193 0.00186 0.00008 0.00021 0.00019 0.00018 0.00106 0.00200 0.00212 0.00204 i Particulate Concentration (uq/m' i Vapor Concentration (u g /m 3) Total Concentration (ug/m3) 0.02000 0.03217 0.05217 0.03752 0.05854 0.09606 0.03665 0.05695 0.09360 0.03554 0.05587 0.09141 EDD0079977

AR226-2423 ATMOSPHERIC MODELING SJjJQIES WASHINGTON WORKS NEAREST LUBECK NEIGHBOR ANNUAL EXPOSURE IS CA. 0.03 UG/M3 <10% CEG) ASSUMING 85% UTILITY/90% EFFICIENCY OF FINE POWDER DRIER SCRUBBER.

AR226-2627 15 AR226-2627 RESULTS OF C8 SAHPLBS FROM Dgl jg3 -GROUND RATER SAMPLES ON THE SITE, OffT-Joag -ao/Ss Sample point C8 ia ppb 93 A B 96 A B C D 98 A B C 0.2 Remark; There is a project for ground 1.0 water treatment to reduce 0.7 several chemicals which are N.D. identified.

AR226-2768 FOR D PONT USE ONLY E.