Final Draft Guidance Document Telomer Research Program (TRP) AR226-1888 Guidance Document Best Analytical Practices for TRP Studies Author Marilyn Stadalius Critical Path Services 300 Foulk Road, Suite 1C Wilmington, Delaware 19803 Completion Date March 2004 RECEIVED OPPT NCIC 2004 DEC 22 AM 11:20 Sponsor Telomer Research Program Asahi Glass Co., Ltd.

SRPT T-6295.8, T-6889.1, T-6316.4 DTI 5-A A Z226-oQ - 3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY Title: Inter-Species Comparison of Mechanisms Fluorochemical Toxicity following Intraperitoneal dosing of perfluorooctanesulfonate (PFOS, T-6295) or ammonium perfluorooctanoate (APFO, T-6889) in Rats and Guinea Pigs and oral dosing of N-ethyl perfluorooctanesulfonamido ethanol (N-EtFOSE, T-6316) in Rats.

AR226-2101 Test Results .

AR226-2252 Mark H.

AR226-2311 Paul R Jann 03/13/2003 01:27 PM To: cc: Subject: Catherine A Barton/AE/DuPont@DuPont Wilfred K Whitcraft/AE/DuPont@DuPont, Charles J Zarzecki/AE/DuPont@DuPont, Mark C Hause/DuPont@DuPont Re: air monitoring Q Cathy, Sometimes you need a little real data to satisfy both the Agency and the public when it comes down to sensitive issue like carcinogen HAPs.

Air Dispersion M odeling Verification Study Oct 22,2003 g tNoa toJ AR226-2346 EXP015790 O b jective Compare results from ambient air sampling and air dispersion modeling to understand how modeling predictions relate to measured ambient air concentrations to0^too1\ to EXP015791 Verification Study Scope Air Sampling Program Analytical Methods Modeling Analysis of Results oNm two EXP015792 Air Sampling Locations Simultaneous coverage of all 4 major wind directions (N, S, E, W) Capture point of predicted maximum concentration from modeling Include co-located samplers at predicted maximum Total of six locations IaoMm to EXP015793 Air Sampling Loc ASH026725 EXP015794 ASH026726 EXP015795 | /* Air Sampling Strategy Measure ambient air levels i 24-hour sampling duration Seven (7) sampling events scheduled over 6 weeks Vary day of week to capture variations in daily operations (none expected) and variations in meteorology Record site-specific meteorological and operational data EXP015796 Monitoring Strategy: Samples taken every 6 days for 6 weeks.

AR226-2574 GROUNDWATER INVESTIGATION QUALITY ASSURANCE PROJECT PLAN FOR WASHINGTON WORKS PLANT Date: January 2002 Project No.: D6WW7423.U1 E !'

FirstChemical Corporation A DuPont Company PASCAGOULA BASELINE STUDY/REPORT FOR FIRST CHEMICAL CORPORATION PASCAGOULA, MISSISSIPPI Date: October 2006 Project No.: 18984786.06051 508800 Pascagoula Baseline Study/Report Table of Contents TABLE OF CONTENTS Executive Summary............................................................................................................1 1.0 Introduction.................................................................................................................1 1.1 Background on PFOA and PFOS......................................................................1 1.2 Report Content.................................................................................................. 2 2.0 Pascagoula Region Water and Solids Sampling........................................................ 3 2.1 Introduction and Background........................................................................... 3 2.2 Water and Solids Field Sampling..................................................................... 3 2.2.1 Surface Water and Wastewater Sampling........................................... 3 2.2.2 Potable and Industrial Water Sampling............................................... 5 2.2.3 Groundwater Sampling........................................................................ 5 2.2.4 Pascagoula POTW Sludge Sampling.................................................. 6 2.3 Laboratory Analysis and Data Review - Water and Solid Samples.................6 2.4 Discussion of Analytical Results...................................................................... 8 2.4.1 Surface Water...................................................................................... 8 2.4.2 Groundwater........................................................................................ 9 2.4.3 Pascagoula POTW Sludge..................................................................10 2.5 General Occurrence of PFOA in the Water and Solids...................................10 2.5.1 Discussion of PFOA Concentrations in Fresh Water.........................10 2.5.2 Discussion of PFOA Concentrations in Salt Water............................11 2.5.3 Discussion of PFOA in Waste Water Treatment Facilities................11 2.6 Summary of Water and Solids Field Sampling...............................................11 3.0 Pascagoula Region Fish and Invertebrate Sampling.................................................13 3.1 Introduction and Background..........................................................................13 3.2 Fish and Invertebrate Field Sampling..............................................................13 3.2.1 Selected Fish Sampling......................................................................13 3.2.2 Selected Invertebrate Sampling..........................................................14 3.3 Laboratory Analysis and Data Review - Fish and Invertebrate Samples.......14 3.4 Discussion of Analytical Results for Fish and Invertebrates..........................15 3.4.1 Fish.....................................................................................................15 3.4.2 Invertebrates.......................................................................................16 3.5 General Occurrence of PFOA in Fish and Invertebrates.................................16 3.5.1 Discussion of PFOA Concentrations in Saltwater Fish......................16 3.5.2 Discussion of PFOA Concentrations in Marine Invertebrates...........17 3.5.3 Bioaccumulation Discussion..............................................................17 3.6 Summary of Invertebrates and Fish Field Sampling.......................................18 4.0 References.................................................................................................................19 S:\Groups\URS\WP\Pascagoula\508800 Baseline Study\Report\FCC BaselineStudyRpt.doc October 2006 i Pascagoula Baseline Study/Report Table of Contents Table 1a Table 1b Table 2 Table 3a Table 3b Table 4 Table 5 TABLES PFOA Summary Water Samples PFOS Summary Water Samples PFOA and PFOS Summary of Solids Sample PFOA Summary Biological Samples PFOS Summary Biological Samples Summary of Background Information on PFOA from the Literature Cited in This Report Biological Sample Sizes Figure 1 Figure 2 FIG URES Baseline Study Sampling Locations Groundwater and Storm Water Sample Locations Appendix A Analytical Data APPEN DICES S:\Groups\URS\WP\Pascagoula\508800 Baseline Study\Report\FCC BaselineStudyRpt.doc October 2006 ii Pascagoula Baseline Study/Report Acronyms ACRONYMS Acronym APFO BCF BAF COC DuPont FCC LC/MS/MS LOD LOQ MDEQ MDL MDMR MS ND NQ Pg/Kg Pg/L ng/g NERR PBS PFOA PFOS POTW Ppb PQL QAPP QC RPD SNUR SOP STL SWPPP WWTP Definition / Description Ammonium perfluorooctanoate Bioconcentration Factor Bioaccumulation Factor Chain of Custody E.

P-1 COMPANY SANITIZED - Does not contain TSCA Confidential Business Information (CBI) DAUUN AZza _ 3730 fi o>2 <> DAIKIN AMERICA, INC. 905 State Docks Road (35601) P.O.

3M Jean B.

INTERIM REPORT #25 - Analysis of Ground Water Samples STUDY TITLE Analysis of Perfluorobutanesulfonate (PFBS), Perfluorohexanesulfonate (PFHS), and Perfluorooctanesulfonate (PFOS) in Water, Soil, Sediment, Fish, Clams, Vegetation, Small Mammal Liver and Small Mammal Serum Using LC/MS/MS for the 3M Decatur Monitoring Program DATA REQUIREMENTS EPA TSCA Good Laboratory Practice Standards 40 CFR 792 STUDY DIRECTOR Jaisimha Kesari P.E., DEE Weston Solutions, Inc. 1400 Weston Way West Chester, PA 19380 Phone: 610-701-3761 INTERIM REPORT COMPLETION DATE November 22,2006 PERFORMING LABORATORY Exygen Research 3058 Research Drive State College, PA 16801 Phone:814-272-1039 STUDY SPONSOR 3M Company 3M Building 0236-01-B-10 St.

Scientific Workshop to Inform the Technical Work Plan for EPA's Response to NAS Comments on the Health Effects of Dioxin presented in EPA's Dioxin Reassessment Cincinnati, OH Date: February 18-20, 2009 Background/Workshop Objective At the request of the U.S.

DRAFT--DO NOT QUOTE OR CITE 5.

2/10/2017 https://www.fsis.usda.gov/wps/wcm/connect/fsis-content/intemet/main/topics/data-coNection-and-reports/chemistry/dioxin-related-activites Dioxin Related Activities General and Scientific Information q?

Cable Viewer Viewing cable 08BOGOTA229, FOREIGN INVESTMENT CONTINUES TO BOOM IN COLOMBIA If you are new to these pages, please read an introduction on the structure of a cable as well as how to discuss them with others.