AR226-1483 CGMW5 !

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Benchmark Doses for Tumors in Sprague Dawley Rats fed N-Ethyl Perfluorooctanesulfonamido Ethanol (N-EtFOSE) Introduction David W.

Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Mallard Test Substance: Perflorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,12.233.44,5.5,6,678-,h7e,pt8a8decafluoro, potassium salt.

`Toxicological Summary PFOS Dietary Chronic Pilot Reproductive Study: Mallard Test Substance: Perfluorooctanesulf(oPnFaOtSe) Structure: p1o-tOacstsanieusmuslaflot,niCcAaSci#d,2719,51-23253..3344,55,6,6,7,8,88-hepladecafluoroTest Remarks: sTthoereedstunsduebrstaamnbcieenistacwohniditteiopnos,wdaenrdp(u3riMtyLowta#s2d1e7t)e.rTmhineesdam{p0bleew8a6s.9% by LC/MS, "H-NMR,andclemental analysis techniques.

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os UIPON January10,2005 Via Federal Express.

TestRe&ults AR226-2125 file:///Cl/WINDOWS/TEMP/Monomets C-8 2-26-73 thiu 8-5-81 9 pagcsAtm Test Results Sample Datd Range Concentration Range Action Level Industrial Hygiene 2Q6/73 8/5/fll 100'A Sampis Dt Sample # Duration Type Employee Name Pers 8TO; LOG; 08 TEFLON 016 MONOMER ANALYZER COMPUTER ROOM 11/15/79 61388 Z 11/26/79 61390 Z 11/29/79 61391 Z Chemical Cone Unit Percent c-a 0.0006 PPM 0.0% C-8 0.0003 PPM 0.0% C-8 0.0004 PPM 0.0% BTO: LOC: 08 TEFLON 023 TRAINING FACILITY (OLD PROD C.C.) 3/3/81 S4817 Z 3/3/61 54818 ' Z 3/16/81 54819 Z 3/17/81 54820 Z 3/18/81 54821 2 3/18/81 54822 Z 3/19/81 54823 Z 3/19/81 54824 Z 3/27/81 54825 Z BTO: LOC ; 08 TEFLON 701 FINE POWDER DRYER-EAST SIDE #2 c-a C.8 C-8 C-8 C-8 08 C-8 C-8 C-8 0.0004 PPM 0.0005 PPM 0.0% 0.0002 PPM 0.0008 PPM 0.0002 PPM <0.0001 PPM 0.0% 0.0003 PPM 0.0% 0.0004 PPM 0.6% <0.0001 PPM 0.0% 0 3 t^ .

AR226-2309 ^y Mark C Hause 03/12/2003 04:25 PM To: cc: Subject: David M Rurak/AE/DuPont@DuPont Catherine A Barton/AE/DuPont@DuPont, Charles J Zarzecki/AE/DuPont@DuPont ISC Model Dave, Per our discussion, I have spoken with Cathie on the need to investigate the model and its validity for 1 and 8 hour periods.

EXPOSURE EVALUATION FOR NEW PROCESS AT FAYETTEVILLE SITE Prepared by DuPont Engineering Technology Debbie Mulrooney Cathie Barton August 20, 2001 Revised February 20, 2002 TABLE OF CONTENTS Executive Summary 1.

3M EnvironmentaLlaboratory FinalReport-AnalyticaSltudy Single-DosDeermalAbsorption/ToxiciStyudyofT-6052 inRabbits In-VivoStudyReferenceNumber: HWI#6329-135 StudyNumber: AMDT-020795.1 TestSubstance:FC-120(T-6052) Name and AddressofSponsor: 3M SCD Division 367 Grove Street St.Pau'1,MN 55106 Name and Address of TestingFacility: 3M Environmental Technology & Services 935 Bush Avenue St.Paul,MN 55106 Method Numbers AMDT-M-1-0, AMDT-M-2-0, AMDT-M4-0, AMDT-M-5-0, AMDT-M-8-0, AMDT-M-14-0, and Revisions: Thermal Extractionof Fluorideby Means of a Modified Dohrrnann DX2000 OrganicHalideAnalyzer-Liver FluorideMeasurement by Means of an Orion EA940 Expandable Ion Analyzer Extractionof Fluorochemicalsfrom RabbitLiver Analysisof RabbitLiverExtractforFluorochemicalsUsing ElectrosprayMass Spectrometry Analysisof FluorideUsing the SkalarSegmented Flow Analyzer with Ion SelectiveElectrode Thermal Extractionof Fluorideby Means of a Modified Dohrmann DX2000 Organic HalideAnalyzer-Serum InitiationDate: See attachedprotocol Author: James D.

3M 3M Corporate Toxicology and 3M Center, Building 0220-06-E-03 Regulatory Services St.

p. 1 Congress reports : EPIDEMY OF ACUTE RESPIRATORY ILLNESS LINKED TO USE . . .

COMPANY SANITIZED - Does not contain TSCA Confidential Business Information (CBI) L!

CaApndorteesV.GoMuarlsienlowski VoiumtaogritotennOtfc Bosngs W0imnregeoer0,te1.o56n%mea `nde nanowsiusa dupont om Em October 16, 2006 VIA FEDERAL EXPRESS TESPACAEaDsotc--uRmeonotmP6r4o2ce8ssing Center (7407M) AUtSt.n: EnSvecitrioonnme8n(te)al~ PFrYo1teCctoioorndiAngaetnocry W1a2s01hiCnogntsotni,tuDt.iCo.n A2v0e0n0ue4,33N0W2 Phone: 202/564-8940 NocBI Re: PFOA (perfluorooctanoic acid) and PFOS (perfluorooctanesulfonate) Sampling Pascagoula, Mississippi Baseline Study/Report (October 2006) Dear FYI Coordinator: YPoleuarseconfivnednieennccleo,seadcaopcyoopfyhoifstehnetiarbeosvueb-mdiesnstiiofnieid astlusdoyp,rosvuibdmeidttoend tfhoereynoculrosiendfoCrDm.ation.