ABD00019810 STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986 CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITY JUNE 2, 2000 The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number No CAS number is given when several substances are presented as a single listing The date refers to the initial appearance of the chemical on the list For easy reference, chemicals which are shown underlined are newly added Chemicals which are shown with a strikeout are chemicals recommended for removal from the list by the "state's qualified experts " CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER Chemical A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) Acetaldehyde Acetamide Acetochlor 2-Acetylaminofluorene Acifluorfen Acrylamide Acrylonitrile Actinomycin D Adriamycin (Doxorubicin hydrochloride) AF-2,[2-(2-furyl)-3-(5-mtro-2-furyl)]acrylamide Aflatoxins Alachlor Alcoholic beverages, when associated with alcohol abuse Aldnn AIM chterwie Delisted October 29.1999 2-Aminoanthraquinone p-Ammoazobenzene ortho-Ammoazotoluene 4-Aminobiphenyl (4-aminodiphenyl) 1-Amino-2,4-dibromoanthraqumone 3-Amino-9-ethylcarbazole hydrochloride 2-Aminofluorene 1-Amino-2-methylanthraquinone 2-Amino-5-(5-mtro-2-furyl)-1,3,4-thiadiazole 4-Amino-2-mtrophenol Amitrole Analgesic mixtures containing phenacetin Aniline Aniline hydrochloride ortho-Amsidme ortho-Amsidine hydrochloride Antimony oxide (Antimony trioxide) Aramite Arsenic (inorganic arsenic compounds) Asbestos Auramme Azacitidine CAS Number 26148685 75070 60355 34256821 53963 62476599 79061 107131 50760 23214928 3688537 -- 15972608 ... 309002 107051 117793 60093 97563 92671 81492 6109973 153786 82280 712685 119346 61825 ... 62533 142041 90040 134292 1309644 140578 ... 1332214 492808 320672 Date January 1, 1990 April 1, 1988 January 1, 1990 January 1, 1989 July 1, 1987 January 1, 1990 January 1, 1990 July 1, 1987 October 1, 1989 July 1, 1987 July 1, 1987 January 1, 1988 January 1, 1989 July 1, 1988 July 1, 1988 January 1,1990 October 1, 1989 January 1, 1990 July 1, 1987 February 27, 1987 August 26, 1997 July 1, 1989 January 29, 1999 October 1, 1989 July 1, 1987 January 29, 1999 July 1, 1987 February 27, 1987 January 1, 1990 May 15, 1998 July 1, 1987 July 1, 1987 October 1, 1990 July 1, 1987 February 27, 1987 February 27, 1987 July 1, 1987 January 1, 1992 ABD00019811 2- - Azaserme Azathioprine Azobenzene Benz[a]anthracene Benzene Benzidine [and its salts] Benzidine-based dyes Benzo[b]fluoranthene Benzo[|]fluoranthene Benzo[k]fluoranthene Benzofuran Benzo[a]pyrene Benzotrichlonde Benzyl chlonde Benzyl violet 4B Beryllium and beryllium compounds Betel quid with tobacco 2,2-Bis(bromomethyl)-1,3-propanediol Bis(2-chloroethyl)ether N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) Bischloroethyl nitrosourea (BCNU) (Carmustine) Bis(chloromethyl)ether Bis(2-chloro-1-methylethyl)ether, technical grade Bitumens, extracts of steam-refined and air refined Bracken fern Bromodichloromethane Bromoform 1,3-Butadiene 1,4-Butanediol dimethanesulfonate (Busulfan) Butylated hydroxyamsole beta-Butyrolactone Cacodylic acid Cadmium and cadmium compounds Caffeic acid Captafol Captan Carbazole Carbon tetrachloride Carbon-black extracts Ceramic fibers (airborne particles of respirable size) Certain combined chemotherapy for lymphomas Chlorambucil Chloramphenicol Chlordane Chlordecone (Kepone) Chlordimeform Chlorendic acid Chlorinated paraffins (Average chain length, C12, approximately 60 percent chlorine by weight) p-Chloroaniline p-Chloroamhne hydrochloride Chtorodibromomethane Delisted October 29. 1999 Chloroethane (Ethyl chloride) 1-(2-Chloroethyl)-3-cyclohexyl-1-mtrosourea (CCNU) (Lomustine) 115026 446866 103333 56553 71432 92875 -- 205992 205823 207089 271896 50328 98077 100447 1694093 -- -- 3296900 111444 494031 154938 542881 -- -- -- 75274 75252 106990 55981 25013165 3068880 75605 -- 331395 2425061 133062 86748 56235 -- -- -- 305033 56757 57749 143500 6164983 115286 108171262 106478 20265967 454484 75003 13010474 July 1, 1987 February 27, 1987 January 1, 1990 July 1, 1987 February 27, 1987 February 27, 1987 October 1, 1992 July 1,1987 July 1, 1987 July 1, 1987 October 1, 1990 July 1, 1987 July 1, 1987 January 1, 1990 July 1, 1987 October 1, 1987 January 1, 1990 May 1, 1996 April 1, 1988 February 27, 1987 July 1, 1987 February 27, 1987 October 29, 1999 January 1, 1990 January 1, 1990 January 1, 1990 April 1, 1991 April 1, 1988 February 27, 1987 January 1, 1990 July 1, 1987 May 1, 1996 October 1, 1987 October 1, 1994 October 1, 1988 January 1, 1990 May 1,1996 October 1, 1987 January 1, 1990 July 1, 1990 February 27, 1987 February 27, 1987 October 1, 1989 July 1, 1988 January 1, 1988 January 1, 1989 July 1, 1989 July 1, 1989 October 1, 1994 May 15, 1998 January 1,1990 July 1, 1990 January 1, 1988 2 ABD00019812 i -3- 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1- nitrosourea (Methyl-CCNU) Chloroform Chloromethyl methyl ether (technical grade) 3-Chloro-2-methylpropene 1 -Chloro-4-mtrobenzene 4-Chloro-ortho-phenylenediamine p-Chloro-o-toluidine p-Chloro-o-toluidine, strong acid salts of 5-Chloro-o-toluidine and its strong acid salts Chloroorene Chlorothaloml Chlorotriamsene Chlorozotocin Chromium (hexavalent compounds) Chrysene C 1 Acid Red 114 C 1 Basic Red 9 monohydrochloride C 1 Direct Blue 15 Cl Direct Blue 218 C 1 Solvent Yellow 14 Ciclosporin (Cyclosporin A, Cyclosporine) Cidofovir Cinnamyl anthramlate Cisplatin Citrus Red No 2 Clofibrate Cobalt metal powder Cobalt [II] oxide Cohalt sulfate hentahvdrate Coke oven emissions Conjugated estrogens Creosotes para-Cresidme Cupferron Cycasin Cyclophosphamide (anhydrous) Cyclophosphamide (hydrated) Cytembena D&C Orange No 17 D&C Red No 8 D&C Red No 9 D&C Red No 19 Dacarbazine Daminozide Dantron (Chrysazin, 1,8-Dihydroxyanthraquinone) Daunomycin DDD (Dichlorodiphenyldichloroethane) DDE (Dichlorodiphenyldichloroethylene) DDT (Dichlorodiphenyltrichloroethane) DDVP (Dichlorvos) N,N'-Diacetylbenzidine 2,4-Diaminoamsole 2,4-Diaminoamsole sulfate 4,4'-Diaminodiphenyl ether (4,4'-Oxydiamline) 13909096 67663 107302 563473 100005 95830 95692 -- -- 126998 1897456 569573 54749905 -- 218019 6459945 569619 2429745 28407376 842079 59865133 79217600 113852372 87296 15663271 6358538 637070 7440484 1307966 10026241 -- -- -- 120718 135206 14901087 50180 6055192 21739913 3468631 2092560 5160021 81889 4342034 1596845 117102 20830813 72548 72559 50293 62737 613354 615054 39156417 101804 October 1, 1988 October 1, 1987 February 27, 1987 July 1, 1989 October 29, 1999 January 1, 1988 January 1, 1990 May 15, 1998 October 24, 1997 June 2. 2000 January 1, 1989 September 1, 1996 January 1, 1992 February 27, 1987 January 1, 1990 July 1, 1992 July 1, 1989 August 26, 1997 August 26, 1997 May 15, 1998 January 1, 1992 January 29, 1999 July 1, 1989 October 1, 1988 October 1, 1989 September 1, 1996 July 1, 1992 July 1, 1992 June 2. 2000 February 27, 1987 February 27, 1987 October 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 February 27, 1987 February 27, 1987 May 15, 1998 July 1, 1990 October 1, 1990 July 1, 1990 July 1, 1990 January 1, 1988 January 1, 1990 January 1, 1992 January 1, 1988 January 1, 1989 January 1, 1989 October 1,1987 January 1, 1989 October 1, 1989 October 1, 1990 January 1, 1988 January 1, 1988 3 ABD00019813 -4- 2,4-Diaminotoluene Diaminotoluene (mixed) Dibenz[a,h]acridine Dibenz[a,j]acridme Dibenz[a,h]anthracene 7H-Dibenzo(c,g]carbazole Dibenzo[a,e]pyrene Dibenzo[a,hjpyrene Dibenzo[a,i]pyrene Dibenzo[a,ljpyrene 1,2-Dibromo-3-chloropropane (DBCP) 2,3-Dibromo-1 -propanol Dichloroacetic acid p-Dichlorobenzene 3,3'-Dichlorobenzidine 3,3'-Dichlorobenzidine dihydrochloride 1,4-Dichloro-2-butene 3,3'-Dichloro-4,4'-diaminodiphenyl ether 1,1-Dichloroethane Dichloromethane (Methylene chloride) 1,2-Dichloropropane 1,3-Dichloropropene Dieldrm Dienestrol Diepoxybutane Diesel engine exhaust Di(2-ethylhexyl)phthalate 1,2-Diethylhydrazine Diethyl sulfate Diethylstilbestrol (DES) Diglycidyl resorcinol ether (DGRE) Dihydrosafrole Dnsopropyl sulfate 3,3'-Dimethoxybenzidine (ortho-Diamsidine) 3,3'-Dimethoxybenzidme dihydrochloride (ortho-Diamsidine dihydrochloride) Dimethyl sulfate 4-Dimethylaminoazobenzene trans-2-[(Dimethylamino)methylimino]-5-[2-(5-mtro-2- furyl)vmyl]-1,3,4- oxadiazole 7,12-Dimethylbenz(a)anthracene 3,3'-Dimethylbenzidine (ortho-Tolidme) 3,3-Dimethylbenzidine dihydrochloride Dimethylcarbamoyl chloride 1,1-Dimethylhydrazme (UDMH) 1,2-Dimethylhydrazine Dimethylvinylchloride 3,7-Dimtrofiuoranthene 3,9-Dimtrofluoranthene 1,6-Dimtropyrene 1,8-Dmitropyrene Dimtrotoluene mixture, 2,4-/2,62,4-Dmitrotoluene 2,6-Dimtrotoluene Di-n-propyl isocinchomeronate (MGK Repellent 326) 1,4-Dioxane Diphenylhydantoin (Phenytoin) 95807 -- 226368 224420 53703 194592 192654 189640 189559 191300 96128 96139 79436 106467 91941 612839 764410 28434868 75343 75092 78875 542756 60571 84173 1464535 -- 117817 1615801 64675 56531 101906 94586 2973106 119904 20325400 77781 60117 55738540 57976 119937 612828 79447 57147 540738 513371 105735715 22506532 42397648 42397659 -- 121142 606202 136458 123911 57410 January 1, 1988 January 1,1990 January 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 January 1, 1988 July 1, 1987 October 1,1994 May 1,1996 January 1, 1989 October 1, 1987 May 15, 1998 January 1, 1990 January 1, 1988 January 1, 1990 April 1, 1988 January 1, 1990 January 1, 1989 July 1, 1988 January 1, 1990 January 1, 1988 October 1, 1990 January 1, 1988 January 1, 1988 January 1, 1988 February 27, 1987 July 1, 1989 January 1, 1988 April 1, 1993 January
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