After each person has read these orders, the shift foreman will lead a discussion of them in the control room.

The tetraethyl lead tank car unloading baildfog it not equipped with a flow alarm or eight-glare on the overflow tank* Mercury waa found behind the teat panel ia the instrument room.

While presumably of high sen sitivity, this technique inevitably leads to serious questions as to the significance of minor physiologic deviations, which must be resolved by studies of morbidity or mortality. vve 000005480 A second approach is to measure the prevalence or incidence of diagnosable illness or morbidity, either in a cross-sectional survey or by analysis of reported illnesses or absenteeisms over a period of time.

Department of Labor Occupational Safety and Health Administration June 1975 OSHA 2225 CTL032565 Endanger d Work rs Mostjob health hazards--such as lead, mercury, and silica--have been recognized for decades or centuries.

lead him to predict that of the roughly 230.0001 asbestos industry workers today, about 93,000 will die unnecessarily of occupational cancer. 77^"' Tvrlcnlfic iruulaaon worjurr# "In.the next 10 to 13 years we will enter the as i sheets outside the room, or mix bestos cancer era." says Dr.

VCM Monltorlnn A VCM monitoring program Is being run by A1 Miguel, the Quality Contr 1 lead man.

Acute Aerosol Inhalation Toxicity of Dow Corning 344 Fluid Albino rats were exposed to Dow Corning 344 fluid for a period of 7-1 hours The aerosol concentration was approximately 90 liter The exposure consisted of an aerosol burst every 1/2 hour for a total _ of 15 exposures over the 7-1 hour period Based on the parameters investigated such as body weight mortality behavioral reactions and gross pathologic examination acute aerosol exposure to Dow Corning 344 fluid appears to present no apparent hazard Day Subacute Aerosol Inhalation Toxicity of Dow Corning 344 Fluid A day subacute aerosol inhalation toxicity study was conducted with 997 using cynomolgus monkeys as experimental animals 1015 was used as treated control material Twelve monkeys were divided equally into two groups designated treated control T T was exposed to the aerosol of Dow Corning 344 fluid and the treated control animals were exposed to the propellent Each inhalation chamber 3.5 cubic meter Plexiglasfi received clean air from the top center of the chamber at a rate of 25 min Each group was exposed to its respective aerosol twice daily each exposure consisting of four second sprays with five minute intervals between sprays for 90 consecutive days The average set of four aerosol releases from the treated control and T were 73.9 and 78.9 grams respectively The average daily nominal concentrations _ were 147.2 and 158.3 mg air for treated control and T respectively Filter samples taken daily from the T chamber revealed an average analytical concentration of 0.005 mg air JNJTALC000479856 During the course of the study animals were observed and data with respect to incidence of mortality food consumption reactions displayed body weight hematologic and clinical blood chemistry profiles urinalyses opthalmic examinations respiratory function tests and neurological examinatiowenrse collected All numerical data from the test group were compared to the treated control group when statistically possible by tests On day 91 of the investiga- tion all animals were given complete gross and microscopic pathologic | examination : No deaths occurred during the experiment and no untoward behavioral reactions were observed Growth as indicated by body weight data was unaffected by exposure to the test compounds No changes in food or water consumption patterns of the animals were observed during the testing program Opthalmic examinations following the exposure periods revealed no treatment ocular lesions confirmed histologically Neurological examinations including evaluation of the righting supporting flexor extensor thrust and patelloar knee jerk reflexes revealendo differences between test and control monkeys Ten lead electrocardiograms conducted during the study revealed no ' abnormalities in.

Regulation expected during 1977 include those on toluene, benzene, cotton dust, trichlorethylene, chloroform, carbon monoxide, noise and "careinqgens" (NIOSH thinks there are about 100 suspected carcinogens), "Guidelines" are expected for lead, mercury, and crystalline silica.

Asbestos exposure may lead to asbestosis. to carcinoma of the lungs and digestive act, and to mesothelioma.

072S ACUTE TOXICITY TO AQUATIC INVERTEBRATES (EASTERN OYSTER) TEST SUBSTANCE_____________________________________________ Identity: AOrecfmetarixrneteudsreutolfcoaonsnitcPaFiancOinidSg), p(FCeCArf-Sl9u5o#,roo2o7rc9at5sa-n3ae9cs-ou3ml)f.opnoantee,ntwohficFhCm-2a0y3.als(1o- be dRiSsiueeFltmthCoyan-2lreek0nsf3oe:.agmClyeuTcrrho,rele3nb%3tuMtinyslofpoedrrotimuhdemaurtc,ioot3icno7tny.in8lld5osi%tuclnafauwtetmeas,tbei0etr,.ri1s2w%a0a%smsoinexdottiuhut rymneloeotlneafedu1.rgy.3llyT4csh%ouellf,Ptae2tFes.6Ot,6sSaan%,md3p5l%e 0.05% tolyltriazole.

xarninat ion : [ J Blood lead f1 n-; -iJ [ ] Chest x-ray, 70 mm [j r1 |j Urine mercury r n * .4 .

We mainly listened and asked leading questions.

(There seemed to me to be a disturbing tendency on the part of Vittone to lead the discussion into the area of accepting a 5-10 ppm standard.)

However, the combination of radio- graphic findings, clinical findings, and pathologic findings lead to the diagnosis of Gaucher's disease.

vehicular maintenance workers lead - 94 active workers 20pg/100ral and below 21-30 31-40 41-50 51-60 >60 CBC's - 104 workers Blood Hemoglobin <13gm wbc < 4800 wbc < 4000 (10 Inactive workers) So. _% 4 (4) 4 (40) 33 (3) 35 (30) 36 (2) 38 (20) 17 (1) 18 (10) 44 00 No. 18 Liver function tests - 102 workers Alkaline phosphatase > 85raU/ml Other abnormality (SGOT > 40, S0PT > 40 and/or Bilirubin > l.0mg%) 24 7- Blood calcium - 102 workers 10,5mg% 5 $$***' ^r .7 .................... i.:; .