(The somewhat unusual situation in which the head of a department in a medical school was also the medical director of an industrial organization, came about many years ago, when Ethyl Corporation was organized by reason of the fact that I had carried out most of the experimental and clinical work on tetraethyl lead arid was, at that time, about the only physician in the country who knew anything about the problem.)

As I told him, and without supporting data at this time, this manganese compound is quite toxic, its toxicity being comparable to that of other rn etallo-organic compounds, including tetraethyl lead.

The precautions advised are of the standard type, and it is only useful to remark that it is of importance that these instruc tions be carried out with minute care against the possibility of intoxication from tetraethyl lead.

We expect to obtain representative samples of material from the sides of the tanks and from the sludge at the bottom In order to assure ourselves in relation to the histories of use of these tanks an to what are the factors which give rise to decomposition of tetraethyl lead in the gasoline, and what quantities of lead are involved.

The precautions advised are of the standard type, and it is only useful to remark that it is of importance that these instruc tions be carried out with minute care against the possibility of intoxication from tetraethyl lead.

In the course of my last trip I looked into acme of these matters in a very discreet manner, and I think there can be no doubt that we must make some detailed observations as to the lead in the atmosphere, and the evidences of lead absorption on the part of some 'well- selected groups of exposed persons* It seems likely that some of your people are aware of this situation, as it may effect the use of tetraethyl lead, but I am convinced that we need to handle the situation with con siderable care.

FILE NAME: Oil Industry and American Petroleum Institute (API) DATE: 1955 May DOC#: API 109 DOCUMENT DESCRIPTION: Trade Journal Article - Industrial Hygiene in the Petroleum Industry s* .

It appears to us that vapor phase cracking and other general methods produce .much more irritating substances than these which occur naturally in petroleum* Huts gasoline is quit variable in'its irritating qualities* Ttmm irritating effects have nothing to do with whether or not tetraethyl lead or Ethyl Fluid a present in the ipaoline* The irritating effeefe depends upon the nature of the gasoline base* As a praetioa^ungestlon it would seem to me advisable to keep Mr* f0KKKkI out of contact with gasoline until M s skin las entirely cleared up* Bland ointments will usually bring bout great improvement unless there is considerable secondary Infection* where such infection 1 presort: and of mild charttor# antiseptic ointments usually clear up the Infection* in severe cases wet dressings are sometimes necessary for a few days* -.."

Kehoe, ' I have recently been asked certain questions about the canister masks used by men employed in the open-air transport of sludge containing tetraethyl lead.

Here, as in the case of tetraethyl lead poisoning, I am much more concerned with prevention than with therapy, although I am certainly not lacking in interest in a satisfactory therapy.

Here, as in the case of tetraethyl lead poisoning, I am much more concerned with prevention than with therapy, although I am certainly not lacking in interest in a satisfactory therapy.

Here, as in the case of tetraethyl lead poisoning, I am much more concerned with prevention than with therapy, although I am certainly not lacking in interest in a satisfactory therapy. .

to TEDP (tetraethyl ditbionopyrophospbate) to TEPP (tetraethyl pyrophosphate).............

Hareh 3, 1959 SU&JJCTi T3 WTERIMS TOO BOT - LEAD To Members of the lead Industries Association!

Hareh 3, 1959 SU&JJCTi T3 WTERIMS TOO BOT - LEAD To Members of the lead Industries Association!