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United Nations Environment Programme 1 p 6~3 UNEPrnOPSiPOPRC .vC1zP . 1 7 November 2005 English only Persistent Organic Pollutants Review Committee First meetin g Geneva, 7-11 November 2005 Agenda item 5 (e ) Considerati on of chemicals proposed for inclusion in Annexes A, B and C of the Convention : perfl uorooctane sulfonate Addendum to the dossier on perfluorooctane sulfonate Submission by Sweden K0540874 081105 For reasons of economy, this document is printed in a limited number.

: AR226-3642 ARRRG. 3638 INTERIM REPORT #1 Analysis of Oskdale Water Samples STUDY TITLE AnalysisofPerfluorooctanoic Acid (PFOA), Perfluorobutanesulfonate (PFBS), Perfluorohexanesulfonate (PFHS), and Perfluorooctanesulfonate (PFOS) in Water, Soil, Sediment, Fish, and Clams Using LC/PMrSo/grMaSmfor the 3M Cottage Grove Monitoring DRAETAQUIREMENTS [EPA TSCA Good Laboratory Practice Standards 40 CFR 792 STUDYDIRECTOR Jaisimha Kesari P.E., DEE We1s4t0o0nWSeosluitoinonWs,ayInc.

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Taft/ Taft Stettinius & Hollister LLP 425 Walnut Street, Suite 1800 /Cincinnati, OH 45202-3957 /Tei : 513 .381 .2838 / Fax : 513 .381 .0205 /www.taftlaw.com Cincinnati / Clevelano / Columbus / Dayton / Indianapolis / Northern Kentucky / Phoenix / Beijing ROBERT A.

COVANCE> FINAL REPORT `CHROMOSOMAL ABERRATIONS IN HUMAN WHOLE BLOOD LYMPHOCYTES `WITH PFOS AUTHOR Hemalatha Murli, PhD PERFORMING LABORATORY Covance Laboratories Inc.

ouzie Perfluorooctane Sulfonic Acid Induced HMG-CoA Reductase in nt and Rat Py DeannCaorJp. oLruaetbekeTro,xiMc.oSl.o,gyA,dv3aMncMeeddiRceasleaDrecphaTrotxmiecnotlogist 3M Center, Building 220-2E-02, Saint Paul, MN 55144 Phone (651) 737-1373 FAX (651) 736-2285 Diluehker@mmm.com Inhibition oR-TF PREFACE "This project is designed toserveboth as a 3M research project and as aprojectto fulfill the requirementsof a Ph.D. thesis in Toxicology through the University of Minnesota "Twin Cities.

- 226 - 1IS2 n#H Te - STUDY TITLE Analysis of Pooled Human Sera and Plasma and Monkey Sera for Fluorocarbons Using - Exygen Method ExM-023-071 DATA REQUIREMENTS .

somenymoeore ComGTon LCR oat lS RsoTlaotrg2iA6a.7tB.ii8cLo%oonTmT TAFT, STETTINIUS & HOLLISTER LLP 425 WALNUT STREET, SUITE 1800 CINCINNATI, OHIO 45202-3957 FA5X:13.53183.13.8216.308208 wwwtaftaw. com AR236 aemaosmarnee unori di g Fax asdor re ousnrio en ema -- 1189 October 29, 2002 TELECOPY AND REGULAR U.S.

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; Paria si THO YEAR ORAL (DIET) TOXICITY / CARCINOGENICITY STUDY OF FLUOROCHEMICAL FC-143 IN RATS (RIKER Experiment No. 0281CRO012) VoLuwe 2 oF 4 ConpucteD DURING AeriL, 1981 - Mav, 1983 RIKER LABORATORIES, Inc. / 3M ConpANY ST.

JEFFERSON MIDICY ens ginoef "DanieolBoaumgh Instittatieosef Anatomy Diet ndChairmen S= i: 6 (aE Oba AR TRECEWED Nov 02:. 1153832 TOXI3COL 3 Philaadetlep)hioa,ie19107 Hoveaber 19, 1982 TDro.xiFcroalongkylinSeDr.viGcersiffith M2Se2Ed0i-c2Pa8al-l0,D2epM3airmtCemesenontttear 55164 DreardDr.havGeripfcfairte ehf:ule ly reVvuibvsecdanccehehdasevbeeleonpieasndtteraqalutaiotCneo.lxyicotFlerosogtnyedtshieanferpteyrseugelovtasanltuoaftcaittohsnese deEe ofEO et, ore atticTihTyeonnttcuilouydreohsuitgehtshattoofFpOarLdoLmdYiuncpeasoevsertno thoaxziacridtytota thcehecodnacmesp.eus even CostinIng voifewFCof143thesneafyacotpsi,niotnh.ere is no need for further developmental toxicology Stncezely, EPT.irvoMefacertssosroh,rallaDannJdiosp?

ARQ26 - 06Sh PFOS Pharmacokinetic - 3 000186 - CRNoordnhi.nng H59u41s5o53n70n7c7545 .

AR 226.- 0792 SEXUTMIMNAGURIYSHFIONRGWAOGREKNTPSEMRAFNOURFMAECDTBUYRTEHDEBGYEMRUMLATINPALREMCYOMOPNANFIOEASM TEST SUBSTANCE Identity: AbemriexfteurrreedcotnotaaisniPnFgOSpe,rfFlCu-o9r5o,ocotraanessaufconaotem, pwhioochfnmFeCa-yn20atl6s.o (1-Octanesulfonic acid) (CAS # 2795-39-3).